STAT

JANUARY 22, 2024

America is over the Covid vaccine. Frantic lineups for scarce doses when Covid vaccines first became available have long since given way to widespread indifference. Each new round of boosters has drawn fewer bared arms than the round before it. The Centers for Disease Control and Prevention estimates that, as of Jan. 6, a mere 21.5% of Americans aged 18 and older and 11% of children have been vaccinated with the latest Covid vaccine.

Vaccines 363

Vaccines 363

ALiEM - Pharm Pearls

JANUARY 22, 2024

A 40-year-old male, tailor by occupation, was brought to the Emergency Department with complaints of high-grade fever for the past 11 days. Fever was documented to be 102°F and was not associated with any chills or rigors. The patient also complained of shortness of breath for one week associated with a dry cough, as well as an altered sensorium for one day.

Documentation 158

Documentation Hospitals 158

STAT

JANUARY 22, 2024

A review of alleged data manipulation in studies involving four top scientists at Dana-Farber Cancer Institute has led to plans to retract six papers and correct 31 manuscripts, the institute confirmed on Monday. The news comes as the famed cancer research and treatment center is now reviewing scores of studies co-authored by some of its leading researchers, including CEO Laurie Glimcher, COO William Hahn, and prominent scientists Irene Ghobrial and Kenneth Anderson.

Hospitals 350

Hospitals 350

PharmaVoice

JANUARY 22, 2024

Demand for infectious disease treatments is projected to grow and challenge trials, when done right, could speed drug development.

Drug Development 163

Drug Development 163

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

STAT

JANUARY 22, 2024

BOSTON — Doctors often don’t have a lot of time to chat with patients during medical appointments — which means that conversations about nutrition can wind up taking a backseat to other concerns. But during a recent weeklong course at Harvard T.H. Chan School of Public Health, preventive cardiologist Stephen Devries enlisted two dozen students in the mission to integrate nutrition into clinical medicine — changing the way medicine is taught and health care is delivere

Diabetes 338

Diabetes Hospitals 338

PharmaVoice

JANUARY 22, 2024

A new study shows that a universal vaccine would lead to huge financial and mortality wins during a pandemic, but development has been slow going.

Vaccines 130

Vaccines 130

The Pharmacist

JANUARY 22, 2024

Almost nine in 10 employed and locum pharmacists are concerned over the potential damage Pharmacy First may have on an ‘already fragile’ workforce in England, a survey by the Pharmacists’ Defence Association (PDA) has revealed. ‘Many’ among the more than 3,500 staff surveyed also said they were worried the ‘hurried’ upcoming service launch could put […] The post Pharmacists concerned Pharmacy First will raise risk of patient abuse appeared first on The Pharmacist.

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STAT

JANUARY 22, 2024

Gilead Sciences said Monday that Trodelvy, its “smart-bomb” medicine that combines an antibody with chemotherapy, did not significantly extend the lives of patients with metastatic non-small cell lung cancer when given after a first treatment failed. The result, from a closely watched study called Evoke-01, will be seen as a disappointment by investors and oncologists alike.

Chemotherapy 318

Chemotherapy 318

The Pharmacist

JANUARY 22, 2024

Community pharmacies are among the 'most likely' places to encounter a case of measles, NHS England (NHSE) has warned. And staff have been instructed to 'take appropriate action' and wear personal protective equipment (PPE) to 'stop onward transmission without delay', when dealing with patients with suspected measles. This comes as the UK Health Security Agency […] The post Wear PPE for suspected measles, pharmacies told appeared first on The Pharmacist.

Community Pharmacies 129

Community Pharmacies Vaccines 129

STAT

JANUARY 22, 2024

In the fall of 2020, Robert Sachs was prescribed a medication to treat prostate cancer that had metastasized into some of his bones. He welcomed the treatment, but was surprised by the $740 monthly copay cost, even after coverage from Medicare and supplemental insurance. So Sachs began reading about the drug, Xtandi , and found the annual list price at the time was about $156,000, or $427 a day, for men with commercial health insurance.

Drug Pricing 306

Drug Pricing 306

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Pharmacy Management

EMCrit Project

JANUARY 22, 2024

background: ANTHARTIC trial Prophylaxis against VAP (ventilator associated pneumonia) has is already supported by a few studies in the literature, perhaps most notably the ANTHARTIC trial. That was a multi-center RCT evaluating 48 hours of therapy with ampicillin-sulbactam for patients intubated following cardiac arrest. Antibiotic therapy reduced early-onset VAP, with a trend towards more ventilator-free […] EMCrit Project by Josh Farkas.

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STAT

JANUARY 22, 2024

You’re reading the web version of Health Care Inc.,  STAT’s weekly newsletter  following the flow of money in medicine.  Sign up  to get it in your inbox every Monday.  Summa wrestling for physician buy-in General Catalyst finally has the hospital system it wants. But there’s some skepticism that the venture capital firm will live up to its promises and get the required buy-in from physicians and other medical staff, my colleague Tara Bannow reports.

Hospitals 282

Hospitals 282

Drug Patent Watch

JANUARY 22, 2024

A recent article published in Health Affairs, delves into the Federal Trade Commission’s (FTC) concerns regarding the inclusion of improper patents in the FDA’s Orange Book by pharmaceutical manufacturers. The… The post Legislative Proposals to Tackle Improper Pharmaceutical Patents in the Orange Book appeared first on DrugPatentWatch - Make Better Decisions.

Pharmaceutical Manufacturing 115

Pharmaceutical Manufacturing 115

STAT

JANUARY 22, 2024

The human blood system is in a constant state of turnover. First-line immune defenders, like neutrophils, need to be replaced after just four to eight hours, platelets can last a week, red blood cells up to four months, and some white blood cells, like memory B cells, live for decades. The heroic task of constantly replenishing these ranks, and making sure the balance of different types of blood cells is right, falls to a primitive reserve of stem cells that reside deep in the bone marrow.

Immunity 270

Immunity Immunization 270

BioPharma Dive

JANUARY 22, 2024

New details of the proposed acquisitions show there were multiple interested buyers, which, according to some analysts, could set the stage for more dealmaking.

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STAT

JANUARY 22, 2024

WASHINGTON — Food and Drug Administration officials hope to finish this year a massive overhaul of the way the agency inspects facilities that make drugs, medical devices, and food products, they said Friday. The reorganization was spurred by the FDA’s mishandling of the infant formula crisis. The agency was slow to inspect a major infant formula plant despite a whistleblower complaint about deadly bacterial contamination at the facility.

Communication 255

Communication 255

Express Pharma

JANUARY 22, 2024

Novo Nordisk and Eli Lilly have been dominating the obesity scene in the past year with the approval of their glucagon-like peptide-1 receptor (GLP-1R) agonists Wegovy and Zepbound. Although medicines with other mechanisms of actions are available on the market, GLP-1R agonists seem to have a greater impact on weight loss and the patient’s life. The development of new weight loss medicines is therefore making great progress, but obesity care needs a much greater revolution, says GlobalData.

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STAT

JANUARY 22, 2024

Getting a new prescription can be overwhelming: medication schedules, foods to eat or avoid, interactions between different drugs. Having all of these details in accessible, printed documents keeps patients informed and mitigates the risk of medication errors. However, there’s a growing movement across the world to eliminate printed medication information, making it harder for patients to learn about the drugs that, in many cases, save their lives.

Documentation 221

Documentation 221

BioPharma Dive

JANUARY 22, 2024

Trodelvy didn’t outperform chemotherapy in a large study of people with a common lung tumor, a setback that sent company shares down by double digits.

Chemotherapy 115

Chemotherapy 115

STAT

JANUARY 22, 2024

Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and invigorating, because now the time has come to dive back in to the usual routine of online meetings, calls, and deadlines. But what can you do? The world, such as it is, continues to spin. So time to give it a nudge in a better direction with a cup or three of stimulation.

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Express Pharma

JANUARY 22, 2024

Cameroon has kickstarted the world’s first routine vaccine programme against malaria. It is one of 20 African countries planning to introduce the drug this year, according to global vaccine alliance Gavi. The RTS,S malaria vaccine, developed by GSK and sold under the brand name Mosquirix, was backed by the World Health Organization in July 2022.

Vaccines 102

Vaccines 102

STAT

JANUARY 22, 2024

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Today, lots of regulatory content! We talk about march-in rights and chastening TikTok influencers for their prescription drug #sponcon.

Drug Pricing 169

Drug Pricing Drug Development 169

Board Vitals - Pharmacist

JANUARY 22, 2024

The American Nurses Credentialing Center (ANCC) and the American Association of Critical Care Nurses (AACN) are the regulatory bodies responsible for conducting exams for individuals aspiring to obtain certification as a nurse practitioner. Both ANCC and AACN certifications serve as proof of the expertise possessed by nurse practitioners. An Adult Gerontology Acute Care Nurse Practitioner (AGACNP) cares for adult patients experiencing acute illness related to a condition.

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STAT

JANUARY 22, 2024

It makes sense in theory for hospitals and startups to strike deals. Not only would doctors get first dibs on new health care technologies, their organizations would see windfalls if those startups hit it big. In practice, it often doesn’t work out that way. Doctors and other clinicians have their own way of doing things, and they typically don’t take kindly to an administrator telling them to learn a new product, especially if the goal is financial gain.

Hospitals 152

Hospitals 152

pharmaphorum

JANUARY 22, 2024

Sandoz makes its first acquisition since spinning out of Novartis, buying a Lucentis biosimilar from Coherus that will boost its position in the US market.

Biosimilars 107

Biosimilars 107

Pharmaceutical Technology

JANUARY 22, 2024

On 18 January 2024, US-based biotech CG Oncology announced it was looking to raise $200m in an upcoming initial public offering (IPO), which will be the first for the biotech sector in 2024.

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pharmaphorum

JANUARY 22, 2024

A hearing will get underway in Delaware later today in the latest phase of GSK’s attempts to defend itself from allegations that its Zantac drug caused cancer in patients.

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European Pharmaceutical Review

JANUARY 22, 2024

Researchers have developed two capillary electrophoresis (CE)-based analytical methods : capillary zone electrophoresis (CZE) and imaged capillary isoelectric focusing (iCIEF) to analyse a broad spectrum of monoclonal antibodies (mAbs) and complex mAb formats. Charge heterogeneity analysis of mAbs and complex formats, such as bispecifics, is “crucial” for therapeutic applications, according to the researchers.

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pharmaphorum

JANUARY 22, 2024

Pharma waste management is crucial for balancing cost, compliance, and environmental responsibility in the healthcare industry. Explore strategies and best practices for effectively managing pharmaceutical waste, while ensuring regulatory compliance and minimising environmental impact.

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Pharma Times

JANUARY 22, 2024

Approximately one in five children will be hospitalised to treat measles

Vaccines 130

Vaccines 130

pharmaphorum

JANUARY 22, 2024

AstraZeneca’s Imfinzi plus bevacizumab and TACE improved PFS compared to TACE alone in hepatocellular carcinoma patients in EMERALD-1, but more data may be needed before approval

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Pharmaceutical Technology

JANUARY 22, 2024

The UK NICE recommends Pfizer's talazoparib, marketed as Talzenna, to treat a specific type of locally advanced or metastatic breast cancer.

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Eye on FDA

JANUARY 22, 2024

Last week FDA’s Office of Prescription Drug Promotion issued its first regulatory action letter of the year. This was an Untitled Letter – a/k/a Notice of Violation Letter (NOV) – sent by the agency to Novartis in relation to promotional content regarding the cancer treatment KISQALI(r) (ribociclib). The communications vehicle that was the subject of the letter was a Direct-to-Consumer (DTC) television advertisement that had been submitted for agency review.

Communication 86

Communication Labelling 86

Pharmaceutical Technology

JANUARY 22, 2024

Sandoz has agreed to acquire Coherus Biosciences' CIMERLI ophthalmology franchise, including proprietary software.

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Outsourcing Pharma

JANUARY 22, 2024

An online portal enabling people worldwide to find and express interest in clinical trials has been launched by Clinical Trial Media, a clinical trial participant recruitment and retention company.

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