STAT

SEPTEMBER 25, 2023

The pressures of the last three and a half years have affected every corner of the health care landscape, but nowhere is the effect more evident than the country’s physician workforce. Burnout, staffing shortages, financial challenges, administrative burden, and two U.S. Supreme Court decisions that stand to stifle diversity and representation in medicine have hamstrung physicians across specialties and settings — in rural and urban communities, in hospitals, clinics, and independe

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Compounding Hospitals 346

PharmaVoice

SEPTEMBER 25, 2023

Despite high rates of disease in older populations, systemic issues are keeping them out of research studies.

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STAT

SEPTEMBER 25, 2023

In the chaotic environment of an emergency room, hospital staffers sometimes face the question of whether to use physical restraints when a patient is experiencing a behavioral crisis. Using restraints is meant to be a last resort in the face of a patient’s agitation in order to keep health care workers and others around them safe. But restraints can also lead to severe adverse outcomes for patients, including physical and psychological trauma.

Hospitals 343

Hospitals 343

ALiEM - Pharm Pearls

SEPTEMBER 25, 2023

66 year-old-male with a history of type 2 diabetes and hypertension presented as a transfer for rapid progression of lower extremity pain, swelling, and blue-purple discoloration of the entire limb with concern for a possible necrotizing infection. His symptoms began earlier in the day and progressed over just a few hours. He had no known thromboembolic risk factors.

Medical Schools 150

Medical Schools Diabetes 150

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

STAT

SEPTEMBER 25, 2023

With physicians experiencing high turnover and burnout during Covid-19 pandemic and rural hospitals closing, the shortage of doctors in rural America keeps getting worse. In 2023, 65% of rural areas had a shortage of primary care physicians, according to a report published by the Health Resources and Services Administration. More than 15% of Americans — about 46 million — live in rural areas, but only 10% of doctors practice in these communities, many of whom are primary care and f

Hospitals 337

Hospitals 337

PharmaVoice

SEPTEMBER 25, 2023

Scientific discovery through new, breakthrough modalities is essential to solve current and future global health challenges – but the path is not easy nor well-defined.

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PharmaVoice

SEPTEMBER 25, 2023

In today’s Biopharma landscape, considering Gross-to-Net is essential for effectively designing and optimizing patient support programs.

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STAT

SEPTEMBER 25, 2023

For months, oncologist Kristen Rice found herself scrambling for cisplatin and carboplatin, two key chemotherapies used for many different cancers including ovarian, bladder, and lung cancer. Like most small community practices, Rice’s clinic has always kept “just in time” inventory – or just enough stock to last the clinic the next few days.

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Pharmacy Technician Chemotherapy Hospitals 299

PharmaVoice

SEPTEMBER 25, 2023

Leaders who’ve created unique strategies for thriving amid the heavy headwinds facing the industry.

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STAT

SEPTEMBER 25, 2023

This was supposed to be the year of the biotech comeback, when promising new medicines and high-dollar buyouts would reverse a sector-wide slump that dates back to 2021. Instead, biotech stocks have dramatically underperformed the broader market, and the year’s few green shoots are yet to grow into a turnaround. The closely watched XBI biotech index has fallen more than 10% in 2023, while the S&P 500 rose about 13% in the same period.

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Pharmacy Management

The Pharmacist

SEPTEMBER 25, 2023

Pharmaceutical company Besins Healthcare has responded to the growing market for hormone replacement therapy (HRT) products by opening a new manufacturing facility in Spain. The UK demand for HRT medicines and their use to alleviate symptoms of the menopause have increased significantly over the last two years, leading to supply interruptions. The new facility will […] The post New HRT facility aims to reduce supply issues appeared first on The Pharmacist.

Pharmaceutical Companies 120

Pharmaceutical Companies Pharmaceutical Companies 120

STAT

SEPTEMBER 25, 2023

Medical students experience significant mental distress, including high rates of anxiety, alcohol use , depression and suicidal ideation , and it’s only gotten worse since the start of the Covid-19 pandemic. The data also show that medical students don’t always get care for these conditions when they need it. And as we found during a recent research study published in JAMA Internal Medicine , the reasons for this are not just stigma and fear of professional repercussions.

Medical Schools 282

Medical Schools 282

Pharma Times

SEPTEMBER 25, 2023

Therapy has been developed to treat adult patients with newly diagnosed multiple myeloma - News - PharmaTimes

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STAT

SEPTEMBER 25, 2023

You’re reading the web edition of Health Care Inc., STAT’s weekly newsletter following the flow of money through the health care system.  Sign up here  to get it in your inbox. Health care’s big labor fight to watch The UAW strike isn’t the only major labor movement in the country. More than 75,000 Kaiser Permanente health care workers will strike next week — Oct. 4 through 6 — if a deal with the health care giant doesn’t come through be

Hospitals 274

Hospitals 274

The Pharmacist

SEPTEMBER 25, 2023

The General Pharmaceutical Council (GPhC) has received instruction by the UK Government to close its temporary Covid-19 register in March 2024. The temporary register was set up in 2020 when the GPhC used its emergency powers to register pharmacy professionals rapidly in response to the Covid-19 pandemic. A stipulation for pharmacy professionals registered on a […] The post GPhC temporary register to close in March 2024 appeared first on The Pharmacist.

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STAT

SEPTEMBER 25, 2023

CommonSpirit Health keeps adding more hospitals — and billions in new debt — even as it bleeds money. Formed through a 2019 merger and headquartered in Chicago, CommonSpirit is one of the country’s largest not-for-profit health systems, with north of 140 hospitals. Even though it has scale, the system has lost money almost every year since its inception, including $2.7 billion on operations in the past two years.

Hospitals 263

Hospitals 263

The Pharmacist

SEPTEMBER 25, 2023

Healthcare professionals should consider stress reduction and mindfulness therapies for patients with high blood pressure, researchers say. Based on the latest clinical and scientific evidence, an international panel of experts from 18 countries have made a series of recommendations on effective lifestyle changes that can help manage and prevent high blood pressure.

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STAT

SEPTEMBER 25, 2023

Editor’s note: A livestream of the event will be embedded below at 1 p.m. ET.  How do we ensure the population in a study best reflects the people who will get a medicine in the real world?

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Pharma Times

SEPTEMBER 25, 2023

Trial involves the use of Padcev and Keytruda among patients with certain types of urothelial cancer - News - PharmaTimes

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STAT

SEPTEMBER 25, 2023

Editor’s note: A livestream of the event will be embedded below at 1 p.m. ET.  How do we ensure the population in a study best reflects the people who will get a medicine in the real world?

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Drug Patent Watch

SEPTEMBER 25, 2023

“Measuring Patent Value Indicators with Patent Renewal Information” aims to address the research gap by constructing a dynamic model that incorporates both ex ante and ex post patent value indicators.… The post Measuring Patent Value Indicators appeared first on DrugPatentWatch - Make Better Decisions.

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STAT

SEPTEMBER 25, 2023

Good morning! This is Jonathan Wosen, West Coast biotech and life sciences reporter, writing to you from sunny San Diego — though the sun won’t be up for another hour or so. I’m filling in for Ed Silverman while he’s away from the Pharmalot campus. And while I may not be a coffee drinker, never fear, as always we’ve got an interesting lineup of news to help kick-start your week.

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Drug Development 190

BioPharma Dive

SEPTEMBER 25, 2023

Agency scientists flagged numerous issues with Brainstorm’s stem cell treatment ahead of a high-profile Wednesday meeting of expert FDA advisers.

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Documentation 117

The Pharmacist

SEPTEMBER 25, 2023

The healthcare super-regulator has escalated concerns over the time it is taking the General Pharmaceutical Council (GPhC) to deal with fitness to practise cases (FtP) to the government. While the Professional Standards Authority (PSA) recognised the GPhC had made some improvements around its handling of FtP cases, it said it had serious concerns over the […] The post GPhC failing to deal with FtP cases quickly enough for a fifth year appeared first on The Pharmacist.

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European Pharmaceutical Review

SEPTEMBER 25, 2023

Nuclear magnetic resonance (NMR) relaxation techniques traditionally used in the food and chemical industries are becoming more relevant to pharmaceutical applications as well. The measured relaxation rate constants resulting from fast chemical exchange between water and exposed NH and OH protons on proteins can be selective to biologics. This has led to applications with biopharmaceutical formulations and protein investigations.

Compounding 96

Compounding Pharmaceutical Companies Pharmaceutical Companies 96

The Pharmacist

SEPTEMBER 25, 2023

Pharmacists are a vital part of the healthcare system and should be supported to do more, the sector has told The Pharmacist on World Pharmacists Day. The day, created by the International Pharmaceutical Federation (FIP), this year focuses on the theme of ‘Pharmacy strengthening health systems’. Pharmacy leaders have taken the opportunity today to celebrate […] The post World Pharmacists Day: pharmacists ‘integral’ to healthcare provision appeared first on The Pharmacist.

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European Pharmaceutical Review

SEPTEMBER 25, 2023

Key attributes of an enterprise resource planning (ERP) system required for drug traceability has been published in a Universal Journal of Pharmacy and Pharmacology paper. Specifically, it described how ERP systems clarify every aspect of operations in a business for drug serialisation compliance. The authors highlighted that this is helpful when setting up infrastructure to implement drug track and trace systems.

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PharmaTech

SEPTEMBER 25, 2023

The Novo Nordisk Foundation will invest up to DKK 950 million (€127 million, US$136 million) in a new cell therapy manufacturing facility in Lyngby, Denmark.

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European Pharmaceutical Review

SEPTEMBER 25, 2023

The European Commission (EC) has approved TEVIMBRA ® (tislelizumab) as monotherapy for adults with oesophageal cancer. The humanised IgG4 anti-PD-1 antibody is indicated for unresectable, locally advanced or metastatic oesophageal squamous cell carcinoma (ESCC) after prior platinum-based chemotherapy. Moreover, the US Food and Drug Administration (FDA) has accepted for review a Biologics License Application (BLA) for tislelizumab as a first-line treatment for patients with unresectable, recurren

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Chemotherapy Immunity Immunization 91

BioPharma Dive

SEPTEMBER 25, 2023

Eisai and Biogen’s anti-amyloid drug is still undergoing regulatory reviews in the EU, U.K. and elsewhere.

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European Pharmaceutical Review

SEPTEMBER 25, 2023

Novartis’ Phase III NETTER-2 trial for its radioligand therapy ( RLT ) Lutathera ® (INN: lutetium ( 177 Lu) oxodotreotide /lutetium Lu 177 dotatate) has demonstrated an ability to offer significant improvement in progression-free survival (PFS) in gastroenteropancreatic neuroendocrine tumours (GEP-NETs). The radioligand therapy is the first to demonstrate clinically meaningful benefit in a first line setting” As a first line treatment, in combination with long-acting octreotide, Lutathera

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Outsourcing Pharma

SEPTEMBER 25, 2023

Mural Health Technologies, Inc. has raised $8 million in seed funding for the growth of its Mural link platform it says is aimed at âmodernizing the clinical trial experience for both patients and caregiversâ.

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Express Pharma

SEPTEMBER 25, 2023

Biosergen AB and Alkem Laboratories have signed a co-development and license agreement for BSG005, an innovative polyene macrolide, through phase II and phase III trials for sale in the Indian market. Biosergen AB is developing BSG005 for the treatment of severe and difficult-to-treat invasive fungal diseases. After the successful completion of two phase I studies, the first patient trial will be conducted in India on patients with severe fungus disease who are intolerant or resistant to treatme

Hospitals 82

Hospitals Drug Development 82

Outsourcing Pharma

SEPTEMBER 25, 2023

Exscientia plc will receive an upfront cash payment of $20 million from Merck KGaA, Darmstadt, Germany, as the companies collaborate plus potential payments of up to $674 million in aggregate.

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Express Pharma

SEPTEMBER 25, 2023

Researchers from Indian Institute of Science Education and Research Bhopal (IISER Bhopal) identified a specific circular RNA (circRNA) called ‘ciTRAN’, which plays a crucial role in multiplication of the AIDS-causing HIV-1 virus within the human body. Led by Dr Ajit Chande from Department of Biological Sciences, IISER Bhopal, this research shows how ciTRAN helps the process of copying genetic information from the virus, essentially helping the virus multiply more efficiently.

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