Tue.Jan 23, 2024

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Abortion funds run short of money as demand soars and donations fall

STAT

The head of the Abortion Fund of Ohio had a sinking feeling as she looked at its end-of-year finances last month. The fund had paid out $1.5 million in 2023 to help close to 4,400 patients get abortions — up from 1,175 the year before — and the pace wasn’t sustainable. If the fund didn’t take a pause for a few weeks, she feared it would run out of money and have to close for good.

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FDA looks to execute ‘largest reorganization in history’ this year

PharmaVoice

What started as an examination of the Human Foods Program has expanded into an agency-wide overhaul.

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Mammograms are less effective for women with dense breast tissue. Medical experts disagree on what to do about it

STAT

Millions of American women over age 40 receive regular mammograms to screen for breast cancer. About half of them turn out to have dense breast tissue — which makes screening significantly more complicated. “It’s kind of a double whammy because dense breast tissue not only makes cancers harder to find, but people with denser tissue are more likely to get breast cancer,” said Laurie Margolies, a radiologist and vice chair for breast imaging at Mount Sinai.

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Don’t forget clinical capacity of non-prescribers, urges GPhC

The Pharmacist

Recommendations made to the parliamentary pharmacy inquiry include giving greater powers to non-prescribing pharmacists to vary prescriptions and freeing up pharmacists for a more clinical, patient-facing role. Speaking to the health and social care committee (HSCC) last week, the chief executive of the General Pharmaceutical Council (GPhC) suggested that changes needed to be made to […] The post Don’t forget clinical capacity of non-prescribers, urges GPhC appeared first on The Pharmacist

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Sanofi scoops up U.S. biotech Inhibrx for up to $2.2 billion as it seeks to bolster pipeline

STAT

LONDON — In a bid to expand its pipeline of inflammation-targeting drugs, Sanofi said Tuesday it was acquiring California-based Inhibrx in a deal worth up to $2.2 billion. The core of the deal is Inhibrx’s experimental therapy for AATD, a disease that progressively damages the lungs and liver. The medicine, INBRX-101, is designed to reduce inflammation and stave off further damage to the tissue.

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FDA orders new cancer warnings for CAR-T therapies

BioPharma Dive

A black box warning for secondary T cell malignancies should be added to the labeling of all six approved CAR-T therapies, the agency said.

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Using Blockchain to Minimize Consumers’ Risk Aversion Toward Generic Drugs

Pharmaceutical Commerce

Study describes how a game theoretic model can successfully analyze how adoption of blockchain technology can reveal quality information.

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STAT+: Pharmalittle: We’re reading about FDA warnings on CAR-T drugs, a Sanofi deal, and more

STAT

Good morning, everyone, and how are you today? We are doing just fine, thank you, despite some cloudy skies hovering overhead. Given that a much-welcomed thaw, of sorts, is under way, there is no need to complain. Of course, some subscribe to the notion that to live is to complain, but we will ignore the philosophers today. Instead, we will reach for another delicious cup of stimulation to brighten our mood.

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NICE backs two AIs for stroke diagnosis in NHS

pharmaphorum

Two artificial intelligence-powered software tools – e-Stroke and RapidAI – have been recommended for use in the NHS to help detect stroke from CT brain scans by NICE. The health technology assessment (HTA) agency said there is some evidence that people admitted to hospital with a suspected had faster or better access to treatment after using the software, although for now it is unclear whether that was a direct consequence of the digital technology.

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Ahead of Medicare drug price reform, pharma’s drug pricing has a Streisand effect

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hello, everyone. Damian here with a look at some polarizing cancer data, a strange CEO transition, and the importance of New Year cheer.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Pharmacist wellbeing ‘has patient safety implications'

The Pharmacist

Patient safety and wellbeing is ‘inextricably bound up’ with the wellbeing of the profession, the chief executive of the General Pharmaceutical Council (GPhC) has told MPs. Duncan Rudkin made the comments as part of an evidence session to the Health and Social Care Committee’s pharmacy inquiry, where together with other pharmacy representatives, he highlighted pressures […] The post Pharmacist wellbeing ‘has patient safety implications' appeared first on The Pharmacist.

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STAT+: A for-profit health system’s financial issues could plunge overburdened hospitals into crisis

STAT

Steward Health Care, a for-profit health system that serves thousands of patients in Eastern Massachusetts, is in such grave financial distress that it may be unable to continue operating some facilities, according to public records and people with knowledge of the situation. The fast-moving crisis has left regulators racing to prevent the massive layoffs and erosion of care that could come if hospital services were to suddenly cease.

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SII joins CEPI global network to boost production of affordable outbreak vaccines

Express Pharma

The Serum Institute of India (SII), is joining a CEPI network of vaccine producers in the Global South to support more rapid, agile, and equitable responses to future public health disease outbreaks. The addition of SII to the CEPI manufacturing network will be a significant boost to vaccine production efforts in Global South regions and will mean the world is better prepared to achieve the 100 Days Mission to develop new vaccines against known or novel infectious diseases within three months of

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Will new therapeutic agent replace antibodies for bacterial detection?

European Pharmaceutical Review

As a tool for detecting and identifying bacteria, aptamers are a promising new class of synthetic nucleic acid molecules that can be used to detect and treat of pathogenic bacteria. With the ability to be developed against a whole bacterium, a microbial toxin, or some proteins, for some bacteria, “aptamers against pathogens can not only supplement the deficiency of antibodies but can also enrich the aptamer database to develop efficient analytical regents”, according to a paper published in the

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Trial raises hopes for simple Alzheimer’s blood test

pharmaphorum

Study finds evidence that an AlZpath immunoassay for phosphorylated tau could deliver an effective blood test for Alzheimer's, paving the way for screening and early treatment

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Researchers advance blood tests’ ability to detect cancer earlier

Pharma Times

The advancement could allow earlier detection of cancer in the blood and better treatment

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Lilly trumpets early success with deafness gene therapy

pharmaphorum

Eli Lilly’s gene therapy for otoferlin-related deafness has restored the hearing of the first child enrolled in its ongoing phase 1/2 trial

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MIT researchers repurpose cancer compound to treat PKD

Pharma Times

Autosomal dominant polycystic kidney disease affects more than 12 million people globally

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Take the hybrid road to bring clinical trials to patients

pharmaphorum

Bringing clinical trials to patients has become easier with the advent of digital technologies and decentralised clinical trials (DCTs). Learn how the hybrid approach combining traditional and digital methods can benefit patients and advance medical research.

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UK MHRA strengthens regulations on fluoroquinolone antibiotics

Pharmaceutical Technology

The UK MHRA has introduced further restrictions on the usage of fluoroquinolone antibiotics, strengthening the previous regulations.

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Sanofi snaps up Inhibrx and its rare disease drug for $2.2bn

pharmaphorum

Sanofi agrees $2.2bn deal to buy California biotech Inhibrx and its long-acting therapy for rare disease AATD, which causes life-threatening emphysema.

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Sustainable nutrition fuses tradition with innovation for environmental and health benefits: GlobalData

Express Pharma

The field of sustainable nutrition is redefining the global food landscape by merging traditional dietary practices with innovative technologies. This evolution, driven by the urgent need for environmental sustainability and enhanced health benefits, is spotlighting alternative food sources and advanced production methods. This transformative trend is not just a fleeting movement but a crucial pivot towards a more sustainable future, finds GlobalData.

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Bayer aims to sustainably improve performance with new organization

World Pharma News

The Bayer Group is introducing a new operating model called "Dynamic Shared Ownership" (DSO) worldwide, which will reduce hierarchies, eliminate bureaucracy, streamline structures and accelerate decision-making processes. The aim of the new operating model is to make the company much more agile and significantly improve its operational performance.

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Covid undervaccination led to thousands of deaths in UK

The Pharmacist

People not having all their recommended doses of the Covid vaccine led to thousands of unnecessary deaths and severe outcomes, researchers have found. Over 7,000 hospitalisations and deaths might have been avoided in summer 2022 if there had been ‘full’ Covid-19 vaccination coverage across the UK, according to a new study. Using health record data […] The post Covid undervaccination led to thousands of deaths in UK appeared first on The Pharmacist.

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Pharma manufacturer Gerresheimer gives Georgia an $88 million injection of funds

Outsourcing Pharma

Manufacturer for the pharma and life sciences industry, Gerresheimer, is investing more than $88 million to expand its operations in Peachtree City, Georgia.

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Genentech signs nanoparticle deal worth up to $644m with GenEdit

Pharmaceutical Technology

Genentech will utilise GenEdit’s non-viral polymer nanoparticles for gene therapy delivery in autoimmune diseases.

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Digital marketing firm Viseven gets private equity backing

pharmaphorum

Ukraine-based digital pharma marketing specialist Viseven gets private equity investment from Horizon Capital

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Lupin gets tentative US FDA approval for Rivaroxaban Tablets USP

Express Pharma

Lupin has received tentative approval from the United States Food and Drug Administration (US FDA) for its Abbreviated New Drug Application for Rivaroxaban Tablets USP, 2.5 mg, 10 mg, 15 mg, and 20 mg, to market a generic equivalent of Xarelto Tablets, 2.5 mg, 10 mg, 15 mg, and 20 mg, of Janssen Pharmaceuticals. This product will be manufactured at Lupin’s Pithampur facility in India.

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Fixing the inequity of drug access outside of the US

pharmaphorum

In this new episode of the pharmaphorum podcast, web editor Nicole Raleigh welcomes guest Cem Zorluhar, CEO of Er-Kim Pharmaceuticals, for a conversation on antimicrobial resistance (AMR) and what the biotech industry should be focussing on in order to address this critical issue outside of the West.

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Saama embeds new features within its AI platform to speed up treatments reaching patients

Outsourcing Pharma

Yesterday (January 22), Saama announced the release of several âgroundbreakingâ features within its AI-driven platform, including generative AI (GenAI) chat and interactive review listings (IRL), that it says create a workflow-driven environment for cross-functional collaboration.

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Attending NHS Health Check linked to ‘significantly lower risk of disease’

The Pharmacist

Attending an NHS Health Check is associated with a lower risk of both death and several diseases, according to a new study. An observational study using UK Biobank participants, published today, found that among those who took up an NHS Health check there was a 19% lower rate of dementia diagnosis and 23% lower risk […] The post Attending NHS Health Check linked to ‘significantly lower risk of disease’ appeared first on The Pharmacist.

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Sano Genetics raises a further $11.4 million for its 'precision medicine revolution'

Outsourcing Pharma

Sano Genetics says it is developing software that will enable âthe precision medicine revolutionâ and has raised $11.4 million in new funding.

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Sanofi to acquire Inhibrx for approximately $1.7bn

Pharmafile

Sanofi and Inhibrx, Inc have announced that they have entered into a definitive agreement for Sanofi to acquire Inhibrx following the spin-off of non-INBRX-101 assets into New Inhibrx. INBRX-101 is a human recombinant protein for the treatment of patients with Alpha-1 Antitrypsin Deficiency (AATD), allowing them to achieve normalisation of serum AAT levels with less […] The post Sanofi to acquire Inhibrx for approximately $1.7bn appeared first on Pharmafile.

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Sanofi to buy Inhibrx in deal worth up to $2.2B

BioPharma Dive

The acquisition will give Sanofi an experimental drug for alpha-1 antitrypsin deficiency, while the rest of Inhibrx's assets will be spun out into a new company.

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New patent for Cubist Pharms drug DIFICID

Drug Patent Watch

Annual Drug Patent Expirations for DIFICID Dificid is a drug marketed by Cubist Pharms Llc and is included in two NDAs. It is available from one supplier. There are six… The post New patent for Cubist Pharms drug DIFICID appeared first on DrugPatentWatch - Make Better Decisions.

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