Wed.Jan 24, 2024

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New chronic Covid study offers insight into which immunocompromised patients are most at risk

STAT

You’ve heard of long Covid, a condition in which the acute infection subsides but troubling symptoms persist. Less well known is chronic Covid: The virus just doesn’t leave, sometimes staying in patients’ bodies long enough to mutate into new variants. This happens to people whose immune systems are compromised, whether through disease or treatment, leaving them vulnerable to infections that last weeks, months, or, in one known case, a year.

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J&J’s 2024 strategy will focus on newer meds to offset Stelara’s patent cliff

PharmaVoice

Executives on the healthcare giant’s full-year earnings call highlighted a strong cash position and incremental dealmaking as a way to get past incoming competition.

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Trending Sources

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Opinion: Defunding liberal arts is dangerous for health care

STAT

If you want an argument in favor of teaching the humanities, I suggest you ask a medical educator. Across the U.S., the age-old debate about the value of a liberal arts education has seemingly devolved into mortal combat, leaving the humanities in dire straits on college campuses. For example, the Atlantic recently reported on West Virginia University’s decision to gut its humanities programming, and the New York Times wondered whether the liberal arts will exist after the budget cuts hap

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Breast cancer tops list of most studied diseases

PharmaVoice

The most studied diseases last year included three types of cancer as research into COVID-19 fell sharply in the post-pandemic era.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Opinion: After 20 years in rehabilitation research, my young daughter’s traumatic brain injury transformed my mind and my career

STAT

In the spring of 2020, my almost 4-year-old daughter Livie sustained a severe traumatic brain injury (TBI) when a tree branch fell on her head in our backyard, devastating our whole family. Returning home after five months in the hospital, the real journey began : How do we best care for and support our daughter, who cannot do any daily activities on her own, cannot walk or talk, and has become cognitively impaired?

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Pharmacy First: Are the floodgates about to open?

The Pharmacist

EXCLUSIVE: With the launch of Pharmacy First in England just days away, an under-pressure community pharmacy sector is torn between welcoming the opportunity and wondering whether patient demand will exceed its capacity. From 31 January, the launch of the highly anticipated service will see patients able to access advice and treatment for seven common conditions […] The post Pharmacy First: Are the floodgates about to open?

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Pharma Horizons: Artificial Intelligence

European Pharmaceutical Review

The first in our inaugural Pharma Horizons report series is dedicated to exploring the latest advances in artificial intelligence (AI) and machine learning (ML) for drug development, pharmaceutical manufacturing and quality control. AI/ML is predicted to be the top technology investment for 60 percent of life sciences companies over the next two years, according to a recent survey 1 from the Pistoia Alliance.

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STAT+: Osteoarthritis might be linked to protein known for its role in Alzheimer’s, study says

STAT

A kind of protein implicated in Alzheimer’s disease might also contribute to the breakdown of cartilage that’s characteristic of osteoarthritis.  In a new study, published in Science Translational Medicine on Wednesday, researchers analyzed tissue samples and joint fluid from 12 people, both those with osteoarthritis and healthy controls.

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Lilly gene therapy finding puts focus on hearing loss treatment pipeline

BioPharma Dive

An 11-year-old boy born deaf can hear after receiving Lilly's genetic medicine. Others, including biotechs in China and Regeneron in the U.S., are taking aim at the same drug target.

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As NIH grant runs out, Dog Aging Project founders look to raise up to $50 million

STAT

The Dog Aging Project , which researchers say could yield promising leads for human longevity research, is at a critical crossroads after the National Institute on Aging declined to renew their grant funding. The massive project has been tracking the aging process of almost 50,000 companion dogs across the country through surveys and a biobank with over 14,000 tissue and other samples.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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The Omni Advantage: A concise roadmap for change, for the people

pharmaphorum

"The Omni Advantage: Accelerating the Behavioural Change with Omnichannel in Pharma Sales Engagement" is a game-changing book by businesswoman Merhnaz Campbell. Discover insights, strategies, and inspiration for pharma sales field team success.

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STAT+: FDA OKs — but doesn’t require — a non-cancer-causing chemical for sterilizing devices

STAT

The chemical used to sterilize half of all medical devices in the United States is also known to cause cancer. After years of deliberating on alternatives, the Food and Drug Administration this month deemed a safer gas , vaporized hydrogen peroxide, a legitimate way to decontaminate devices.  It’s a small step in pushing the medical device industry away from the carcinogenic chemical, called ethylene oxide.

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CG Oncology is first biotech IPO of 2024, raising $380m

pharmaphorum

CG Oncology completes the first biotech IPO of 2024, raising $380 million for its oncolytic virus bladder cancer immunotherapy.

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Lilly’s gene therapy restores hearing in an 11-year-old, paving way for more treatment

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hey there. So, today we talk about how Eli Lilly’s gene therapy, developed by Akuous, worked in a child born with an inherited form of deafness. Also, we see some interesting biopharma trends from Stifel, and consider Novo Nordisk’s new obesity investment that is tangential to GLP-1s.

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Over 500,000 women have accessed HRT through pre-paid certificates

The Pharmacist

More than half a million women in England have accessed hormone replacement therapy (HRT) via the HRT pre-payment certificate (PPC) since its introduction last spring, the government has announced. The PPC scheme was launched on 1 April 2023, reducing prescription costs for eligible HRT items to £19.30 a year. Calculations from the Department of Health […] The post Over 500,000 women have accessed HRT through pre-paid certificates appeared first on The Pharmacist.

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STAT+: Pharmalittle: We’re reading about Lilly’s gene therapy for hearing, Shkreli’s life-long ban, and more

STAT

Good morning, everyone, and how are you today? We are doing just fine, thank you. Given that this is already the middle of the week and we have survived this far, no reason not to continue, yes? Just consider the alternatives. In fact, this modest accomplishment calls for celebration. So please join us in quaffing a ritual cup of needed stimulation.

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New government strategy targets medicine supply chain disruption

The Pharmacist

A new plan aiming to shore up the UK’s supply of pharmaceuticals has been unveiled by the government. As part of the Department for Business and Trade’s (DBT’s) recently launched Critical Imports and Supply Chains Strategy, an online portal will be set up to allow importers of essential goods – including medicines and healthcare supplies […] The post New government strategy targets medicine supply chain disruption appeared first on The Pharmacist.

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Venus Remedies gets GMP certification from Libya

Express Pharma

Venus Remedies has received Good Manufacturing Practices (GMP) certification for its facilities from the Ministry of Health, Libya. Saransh Chaudhary, CEO of Venus Medicine Research Centre, said, “The GMP certification from Libya adds to Venus Remedies’ portfolio of international approvals from 25 regulators, complementing our existing certifications in Africa from Morocco, South Africa, Tanzania, Kenya, Uganda, Sudan and other African countries.

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2023 ABIM Pass Rates: How Difficult are the ABIM Exams?

Board Vitals - Pharmacist

The American Board of Internal Medicine (ABIM) offers initial certification exams across 19 medical specialties. Newly released pass rate data for 2023 sheds light on trends and challenges faced by healthcare professionals pursuing board certification. These statistics provide some extra insight on just how difficult the ABIM board exams are, and the importance of adequate exam prep.

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KBI Biopharma and Argonaut Manufacturing Services Team Up on Drug Substance and Drug Product Manufacturing Solutions

PharmaTech

Under a new alliance, KBI Biopharma and Argonaut Manufacturing Services will combine their strengths to offer end-to-end biopharma development and CGMP manufacturing solutions.

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Episode 890: How to Succeed at Journal Club Without Really Trying

Pharmacy Joe

In this episode, I’ll discuss how to guarantee you pick a great article for the journal club. Subscribe on iTunes , Android , or Stitcher There are two important criteria that are essential to fulfill when presenting an article to a journal club: 1. The article should be of high quality 2. The article should be relevant to clinical practice When an article meets these criteria, all parties at the journal club should benefit.

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A year of major M&A ahead?

pharmaphorum

Is the upcoming year set to be a year of major expansion, acquisitions, and deal-making in the business world? Stay informed about the potential trends and opportunities that await in the M&A landscape.

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Bridging the gap between the promise of technology and reality - Lokavant's hopes for SCOPE

Outsourcing Pharma

Andrew Mills, executive vice president of global commercial Lokavant and says the company can help businesses identify risk trends in trials much earlier than traditional methods.

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BenevolentAI names pharma vet Jörg Möller as its new CEO

pharmaphorum

BenevolentAI’s search for a new chief executive has concluded with the appointment of industry bigwig Dr Jörg Möller to the role, four months after Joanna Shields stepped down and as the company emerges from a restructuring drive. The UK artificial intelligence specialist said in a statement that Möller is “an accomplished R&D leader and champion of the application of AI to drug discovery.

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Accent Therapeutics secures funding to advance cancer therapies

Pharmaceutical Technology

Accent Therapeutics has raised $75m in a Series C financing round to progress the development of precision cancer therapies.

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LEO says chronic hand eczema drug bests its only rival

pharmaphorum

LEO Pharma's chronic hand eczema drug delgocitinib has outperformed the only approved drug for the condition in a phase 3 trial.

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48 per cent of healthcare, pharma cos set to integrate first-Gen AI solution within next year: EY Report

Express Pharma

According to the EY report, 60 per cent of survey participants from the healthcare and life sciences sector believe Gen AI will have a significant impact on the entire value chain. The report, titled, ‘The AIdea of India: Generative AI’s potential to accelerate India’s digital transformation,’ highlights that while healthcare and life science sector has been traditionally conservative in adopting digital technologies, a gradual shift is underway.

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Pharma at a critical crossroads in approach bringing new medicines to market, says OM1's CCO

Outsourcing Pharma

OM1 says it wants to stand at the helm of a healthcare revolution, fostering an integrated approach to generating and utilizing real-world evidence (RWE), reshaping the foundation of healthcare.

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Siemens Healthineers, IISc launch laboratory for AI in precision medicine

Express Pharma

Siemens Healthineers and the Indian Institute of Science (IISc) inaugurated the Siemens Healthineers-Computational Data Sciences (CDS) Collaborative Laboratory for AI in Precision Medicine at IISc Bangalore today. Peter Schardt, Chief Technology Officer of Siemens Healthineers, inaugurated this laboratory. The CDS collaborative laboratory will develop open-source AI-based tools to precisely automate the segmentation of pathological findings in neuroimaging data, with a focus on accurately diagno

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4DMT secures rare paediatric designation for cystic fibrosis gene therapy

Pharmaceutical Technology

The company could be in line for a priority review voucher if 4D-710, currently in Phase I/II clinical trials, is approved.

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Advarra at SCOPE - excited to hear about site and sponsor technology coordination

Outsourcing Pharma

Elisa Cascade is chief product officer at Advarra, a business that says it aims to advance the way clinical research is conducted by bringing life sciences companies, CROs, research sites, investigators, and academia together at the intersection of safety, technology, and collaboration.

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BARDA backs Locus phage therapy for resistant E coli

pharmaphorum

BARDA has given $24 million to Locus Bio to support a mid-stage trial of bacteriophage therapy LBP-EC01 for resistant E coli infections.

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NHS to test new blood group genotyping test on inherited blood disorder patients

Pharma Times

Patients living with sickle cell disease and thalassaemia will be eligible for the test

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SCOPE 2024 - a great place to hear best practice and move the needle for life sciences

Outsourcing Pharma

Veevaâs Jim Reilly, vice president is Veeva Development Cloud strategy and along with countless others is getting excited about SCOPE 2024.

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First-of-a-kind psoriasis study outcomes revealed

European Pharmaceutical Review

Topline data from a novel Phase III study show that the biologic TREMFYA ® (guselkumab) facilitated rapid and significant clearance in moderate to severe scalp psoriasis ( PsO ) and significant improvement in scalp itch at 16 weeks, according to Johnson & Johnson. It is the first prospective, large-scale, randomised-controlled clinical trial evaluating people of colour across all skin tones with moderate to severe plaque PsO and scalp PsO to objectively measure clearance and other treatment

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