STAT

APRIL 24, 2023

A new book on the U.S. response to the Covid-19 pandemic paints a picture of a country ill-prepared to cope with a dangerous biological foe, riven by partisan politics, and led by people who saw little political gain in taking ownership of managing the crisis. It also describes a country that remains ill-equipped to battle the next pandemic or major disease threat, though it lays out changes that could strengthen the country’s position.

362

362

PharmaVoice

APRIL 24, 2023

Two decades after the Human Genome Project, scientists are on the brink of uncovering its full potential for drug development.

Drug Development 245

Drug Development 245

STAT

APRIL 24, 2023

Marburg could soon become the second virus in the past year to have experimental vaccine candidates ready for testing under an emergency use listing. Until this point, no licensed vaccines or treatments are available for Marburg. That was also the case with the Sudan strain of Ebola, which caused an outbreak in Uganda with 164 cases and more than 55 deaths in the last quarter of 2022.

Vaccines 218

Vaccines 218

PharmaVoice

APRIL 24, 2023

Dr. Preeti Parikh sees parallels between promoting health equity and current DE&I challenges in the workplace.

246

246

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

Pharmaceutical Technology

APRIL 24, 2023

Traditional medicine refers to the knowledge, skills and practices that indigenous and different cultures use to maintain health, encompassing forms such as herbal medicine, Traditional Chinese Medicine (TCM) and acupuncture. While 80% of the world’s population practices some form of traditional medicine, according to the World Health Organization (WHO), the practice is regularly discredited due to a lack of scientific support and regulation as well as evidence of negative side effects with cert

Compounding 105

Compounding Chemotherapy 105

PharmaVoice

APRIL 24, 2023

Tuberculosis control and funding lost 20 years of progress during the COVID-19 pandemic, but scientists and world health groups are still plugging away.

130

130

Community Pharmacy

APRIL 24, 2023

There are few systems in the human body more sensitive—or important—for a healthy, balanced sense of physical well-being than our GI (gastrointestinal) tract. Each day our digestive system processes what we consume while distributing key nutrients throughout the body. Our gut health affects everything from our immune system, metabolism, and mental health, so it’s worth taking the time to ensure a healthy GI tract.

Community Pharmacies 96

Community Pharmacies Immunity Immunization 96

Pharmaceutical Technology

APRIL 24, 2023

The Covid-19 pandemic pushed the healthcare industry toward rapid digitalisation, with the rise of telehealth, telepresence systems, remote diagnostics, predictive AI, and wearable technology now changing the way healthcare is delivered and improving patient outcomes. Emerging technologies such as AR and VR are becoming increasingly routine for professional training, surgical assistance, and treatment for psychological and neurological disorders.

Hospitals 95

Hospitals 95

European Pharmaceutical Review

APRIL 24, 2023

Included in this issue of European Pharmaceutical Review : FOREWORD New quality requirements for tobacco products David Elder, David P Elder Consultancy QA/QC MASS SPECTROMETRY The benefits of mass spectrometry for expediting biologics to patients Ian Anderson, Mostafa Zarei and Qifeng Zhang, Lonza IN-DEPTH FOCUS: Bioprocessing/Bioproduction Realising the potential of AAV gene therapies Rajiv Vaidya, Andelyn Biosciences What gene therapy manufacturers can gain from collaboration Neil Almstead,

Drug Development 94

Drug Development 94

The Honest Apothecary

APRIL 24, 2023

Here I share some of the latest news, articles, editorials, or blog posts that fall generally under the theme of Pharma or healthcare. I might throw in a something off-topic from time to time which I found while wandering throughout the endless hallways and corridors of the internet. All article shared will be free to read and not locked behind an annoying paywall.

Compounding 91

Compounding Labelling Hospitals 91

Advertisement

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

Pharmacy Management

European Pharmaceutical Review

APRIL 24, 2023

Realising the potential of AAV gene therapies Dr Rajiv Vaidya, Head of Manufacturing Science & Technology at Andelyn Biosciences, explores strategies for improving the scalability and cost‑effectiveness of AAV production while maintaining regulatory compliance. What gene therapy manufacturers can gain from collaboration Neil Almstead, Chief Technical Operations Officer at PTC Therapeutics, shares his view on why collaboration is key to streamlining manufacture of gene therapies.

93

93

BioPharma Dive

APRIL 24, 2023

Submission of the application comes weeks after rivals Vertex and CRISPR filed their gene editing medicine for the disease with the agency.

102

102

European Pharmaceutical Review

APRIL 24, 2023

Included in this Guide to Testing: Exploring low endotoxin recovery in drug products Chiara Celli, Marco Mingolla and Fabrizio Lecce from the Institute of Biomedical Research Antoine Marxer, discuss low endotoxin recovery in drug products analysed using the monocyte activation test. Sustainability in BET from your endotoxin experts Associates of Cape Cod International, Inc. explores the future of sustainable LAL testing.

85

85

Pharma Times

APRIL 24, 2023

MDG1011 is a therapy which aims to improve outcomes for in patients with high-risk blood cancers

109

109

Express Pharma

APRIL 24, 2023

GlaxoSmithKline Pharmaceuticals (GSK) announced the launch of Shingrix (Zoster Vaccine Recombinant, Adjuvanted) in India, for the prevention of shingles (herpes zoster) and post-herpetic neuralgia in adults aged 50 years and above. Shingrix is a non-live, recombinant subunit vaccine to be given intramuscularly in two doses. Shingles are caused by the reactivation of the varicella-zoster virus (VZV), the same virus that causes chickenpox.

Vaccines 82

Vaccines Diabetes Immunity Immunization 82

Pharma Times

APRIL 24, 2023

Treatment involves the treatment of adults with metastatic castration-resistant prostate cancer

109

109

PharmExec

APRIL 24, 2023

Cost Plus Drug Co. adds J&J's Janssen medications to its offerings, increasing affordability for diabetes patients.

Diabetes 98

Diabetes 98

PhRMA

APRIL 24, 2023

If we needed any more proof that the health insurance and pharmacy benefit manager (PBM) industries are one and the same, look no further than a new ad campaign by America’s Health Insurance Plans (AHIP). With PBMs facing increasing scrutiny on Capitol Hill, AHIP is hitting the airwaves to deflect any responsibility for the high cost of medicine many people face.

76

76

BioPharma Dive

APRIL 24, 2023

The divestment of Baqsimi to Amphastar could net Lilly more than $1 billion if sales goals are met.

Diabetes 104

Diabetes 104

PhRMA

APRIL 24, 2023

Nonprofit hospitals are supposed to help provide access to crucial treatment and services in our most vulnerable communities. But recent research adds to the mountain of evidence showing nonprofit hospitals continue to fall short in their community benefit. For example, many nonprofit hospitals participate in the federal 340B Drug Pricing Program, where eligible large nonprofit hospitals can buy deeply discounted 340B medicines and then turn around and charge both uninsured patients and insuranc

Hospitals 74

Hospitals Drug Pricing 74

Pharmafile

APRIL 24, 2023

AbbVie has shared positive results from its phase 3 ELEVATE study, which assessed atogepant for the preventative treatment of episodic migraines in patients who have previously had two to four unsuccessful classes of oral preventive medications. The study results demonstrated that adult patients treated with the atogepant 60mg dose once daily experienced a decrease of 4.2 days in their mean monthly migraine days (MMDs) across the 12-week treatment period compared to the placebo group.

71

71

BioPharma Dive

APRIL 24, 2023

Empowering people to live healthier goes beyond developing the right treatments.

102

102

Pharmaceutical Technology

APRIL 24, 2023

Vallon Pharmaceuticals has concluded the previously announced merger of its operations with biotechnology firm GRI Bio. With work on the agreement, announced in December 2022 , now complete, the combined entity will operate under the brand of GRI Bio. It will support the further development of GRI Bio’s natural killer T (NKT) cell modulators pipeline, to treat inflammatory, fibrotic and autoimmune diseases.

64

64

World Pharma News

APRIL 24, 2023

Targeting part of an antiviral pathway triggered by the accumulation of a key pathogen shared in Alzheimer's disease and frontotemporal dementia may one day offer a new therapeutic approach to deterring or delaying cognitive decline, according to preclinical research led by Weill Cornell Medicine scientists.

70

70

Big Molecule Watch

APRIL 24, 2023

In March 2023, the FDA issued a final guidance , titled “Q13 Continuous Manufacturing of Drug Substances and Drug Products” that describes scientific and regulatory considerations for the development, implementation, operation, and lifecycle management of continuous manufacturing (CM).” CM refers to “the continuous feeding of input materials into, the transformation of in-process materials within, and the concomitant removal of output materials from a manufacturing process.

Biosimilars 62

Biosimilars 62

BioPharma Dive

APRIL 24, 2023

The FDA has approved the pharma, which has had difficulty producing radiopharmaceutical drugs, to make its treatment Pluvicto at a New Jersey site.

68

68

Pharmafile

APRIL 24, 2023

Sanofi has introduced a hepatitis A vaccine for children aged between one to 15 years old in the UK. The vaccine, inactive AVAXIM Junior, will consist of two doses injected intramuscularly six to 36 months apart. The doses can, however, be given up to seven years apart. Hepatitis A is caused by the hepatitis A virus and is primarily transmitted through contaminated food and water, or by direct contact with an infected person.

Vaccines 58

Vaccines Communication 58

BioPharma Dive

APRIL 24, 2023

A second-generation treatment called eplontersen halted nerve damage and improved quality of life in a late-stage study the companies are using to seek U.S. approval.

59

59

Pharmafile

APRIL 24, 2023

The National Institute for Health and Care Excellence (NICE) has recommended Janssen’s imbruvica (ibrutinib) alongside venetoclax as a treatment option for untreated chronic lymphocytic leukaemia (CLL) in adult patients. Ibrutinib is a tyrosine kinase inhibitor (TKI) therapy, which blocks Bruton’s tyrosine kinase (BKT), which is needed by cancer cells to multiply and spread.

Communication 58

Communication 58

The Guardian - Pharmaceutical Industry

APRIL 24, 2023

Queensland pilot program has been made permanent with Victoria and NSW to begin similar trials Get our morning and afternoon news emails , free app or daily news podcast The You Deserve More campaign from the Australian Medical Association has an alarming message: allowing pharmacists to prescribe a wider range of medicines is a threat to patient safety and undermines the health system.

Vaccines 58

Vaccines 58

PharmaState Academy

APRIL 24, 2023

Written By: Vivek Hattangadi My wife Veena is very fond of Kesar mangoes. This is variety of mangoes from Saurashtra, which is always her favorite and according to her, out-beats Hapus in taste. In the past she purchased a carton containing nine to ten kilos from our next-door Capricorn Bazaar. This turned out to be cheaper than when you buy lose. This apart a carton could last 8 to 10 days which saved the hassles of going to Capricorn Bazar every day.

Diabetes 52

Diabetes Hospitals 52

Drug Patent Watch

APRIL 24, 2023

Annual Drug Patent Expirations for DUTREBIS Dutrebis is a drug marketed by Merck Sharp Dohme and is included in one NDA. There are five patents protecting this drug. This drug… The post New patent expiration for Merck Sharp drug DUTREBIS appeared first on DrugPatentWatch - Make Better Decisions.

52

52

PharmaState Academy

APRIL 24, 2023

Note: You can participate only 1 time. Participation by using another name & email id will lead to disqualification. The winner will be announced after profile verification. Once you're a winner, you will not be considered for the prizes for another two months. Note: You can participate only 1 time. Participation by using another name & email id will lead to disqualification.

52

52

Pharmaceutical Commerce

APRIL 24, 2023

The platform agnostic CGT hub hopes to streamline the path-to-care process, by providing physicians and patient services teams with visibility across the therapy development and delivery process.

52

52

Pharmaceutical Technology

APRIL 24, 2023

The UK’s National Institute for Health and Care Excellence (NICE) has recommended the use of AbbVie and Johnson & Johnson’s Imbruvica as part of a combination therapy with venetoclax in previously untreated chronic lymphocytic leukaemia (CLL), based on final draft guidance published on 21 April. The British institute that oversees a therapy’s cost-effectiveness opted for the recommendation based on clinical data from the Phase II CAPTIVATE and the Phase III GLOW studies.

52

52