Tue.Jun 20, 2023

article thumbnail

STAT+: ‘It’s beyond unethical’: Opaque conflicts of interest permeate prescription drug benefits

STAT

Employers across the country — from big names like Boeing and UPS to local school systems — pay consulting firms to handle a straightforward task with their prescription drug coverage: Get the best deals possible, and make sure the industry’s middlemen, known as pharmacy benefit managers, aren’t ripping them off with unfair contracts.

article thumbnail

AI has secured a footing in drug discovery. Where does it go from here?

PharmaVoice

The AI revolution is bringing a new era of drug discovery, and the potential for more uses is greater and faster than ever before.

271
271
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Opinion: Bloated patient records are filled with false information, thanks to copy-paste

STAT

I recently took care of a patient whose medical records included multiple notes about her past open-heart surgery. Only she had never undergone open-heart surgery.

article thumbnail

The spotlight is on accelerated approvals — now FDA could run a tighter ship

PharmaVoice

As the fallout of the Aduhelm approval continues, scrutiny of the speedier pathway has increased and the pressure is on to close a key gap in the regulation.

190
190
article thumbnail

Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

article thumbnail

STAT+: Eli Lilly to acquire DICE Therapeutics in $2.4 billion deal

STAT

Eli Lilly said Tuesday that it will purchase DICE Therapeutics, a small company developing an experimental pill to treat psoriasis, for $2.4 billion in cash. The deal price of $48 per share represents a 42% premium to DICE’s closing price Friday. “In combination with its novel technology and expertise in drug discovery, DICE’s talented workforce and passion for innovation will enhance our efforts to make life better for people living with devastating autoimmune diseases,

220
220
article thumbnail

3 pressing molecular bioanalysis factors confronting gene therapy developers

PharmaVoice

It’s exciting to be part of today’s gene therapy development community; however, three issues are at the top of the industry’s mind—the regulatory landscape, critical molecular bioanalysis considerations: biodistribution, transgene expression, vector shedding and assay-related challenges.

130
130

More Trending

article thumbnail

WHO grants emergency use listing to SK bioscience’s SKYCovione

Pharmaceutical Technology

The World Health Organisation (WHO) has granted an emergency use listing (EUL) to SK bioscience’s Covid-19 vaccine, SKYCovione. SKYCovione is a self-assembled nanoparticle vaccine and the 12th Covid-19 vaccine to receive a EUL from the regulator. Developed using pharmaceutical company GSK’s pandemic adjuvant, the vaccine targets the receptor-binding domain of the SARS-CoV-2 spike protein.

Vaccines 145
article thumbnail

STAT+: Pharmalittle: Opaque conflicts permeate prescription drug benefits; Sanofi prevails in Zantac arbitration

STAT

Rise and shine, everyone, another busy day is on the way. We can tell by the number of people walking past and cars whizzing by the Pharmalot campus this morning. These are among our usual proxies for gauging the state of the world outside our window. All of this is to say there is much to do. So time to get cracking. We are firing up the coffee kettle and brewing a cup of stimulation — salted caramel mocha is the choice right now — and digging out the to-do list.

216
216
article thumbnail

Patient death spurs FDA to pause test of Arcellx’s Gilead-partnered cell therapy

BioPharma Dive

The company said limitations on "bridging treatment" used to hold cancer in check could be to blame, and is working with the FDA to change the study's protocol.

105
105
article thumbnail

STAT+: The FDA is testing new nutrition labels on the front of food packages

STAT

WASHINGTON — The FDA wants to make it easier for consumers to know if the foods they’re buying are unhealthy — but doing so is harder than it seems here in the United States. Much of the Americas already has so-called front of package labels — small symbols printed on packaged foods that alert consumers when a food is high in certain unhealthy nutrients like sodium or saturated fat.

Labelling 212
article thumbnail

5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

article thumbnail

Cell and gene therapy manufacturing: the next generation of startups

BioPharma Dive

Joining larger CDMOs like Lonza and Catalent, a new group of companies aims to capitalize on persistent bottlenecks in producing complex genetic treatments.

108
108
article thumbnail

STAT+: Top federal lobbyist at PhRMA leaves

STAT

WASHINGTON — The top federal lobbyist for the brand drug lobby PhRMA is leaving, two drug industry lobbyists and one health care lobbyist told STAT on Tuesday. Anne Esposito, who was the trade group’s senior vice president for federal advocacy, played an important role in shaping PhRMA’s lobbying strategy over her three and a half years at the organization.

article thumbnail

FluoGuide announces head and neck cancer therapy results

Pharma Times

The treatment is administered intravenously prior to surgery, lighting up cancer during surgery - News - PharmaTimes

118
118
article thumbnail

STAT+: Exact Sciences touts accuracy of updated Cologuard cancer test, but experts want more data

STAT

An updated version of Exact Sciences’ stool-based colorectal cancer screening test detected cancer accurately in a massive study, triggering fewer false alarms than its current product, the company announced Tuesday. While the biotech plans to use the data to apply for regulatory approval, cancer specialists say they’ll need to see more details before concluding the new test is a real and meaningful improvement over the current one.

177
177
article thumbnail

Advancing research on human immune systems in India to develop better vaccines

Express Pharma

The vaccine efforts of the COVID-19 pandemic highlighted our knowledge about gaps in the immune system. Reductionist systems, such as genetically identical inbred mice, have long been the choice for immunology research, which focuses on studying the cells, tissues, and organs that make up the immune system. However, the spotlight has shifted to unravelling the complexities of the human immune system.

article thumbnail

Catalyst licenses Santhera Pharma’s vamorolone in North America

Pharmaceutical Technology

Santhera Pharmaceuticals and Catalyst Pharmaceuticals have signed an exclusive licence and collaboration deal for Santhera’s vamorolone in the US, Canada and Mexico. Catalyst Pharmaceuticals will gain exclusive rights to commercialise vamorolone across the region. The investigational drug candidate vamorolone has a mode of action based on binding to the same receptor as glucocorticoids while changing its downstream activity.

98
article thumbnail

Lilly buys oral immune drug developer Dice Therapeutics for $2.4B

BioPharma Dive

The deal adds to recent M&A activity as well as signals pharma’s continued interest in pills for inflammatory conditions, which are meant to approach the potency of injectable therapies.

article thumbnail

BioSenic to deliver news on copper-arsenic trioxide combination

Pharma Times

Immunological disorder therapy data to be shared at International Conference on Redox Medicine - News - PharmaTimes

109
109
article thumbnail

New data shows ongoing ‘burden’ of supply issues on pharmacies and patients

The Pharmacist

Fresh concerns have been raised around the ‘burden’ of medicine supply issues for both pharmacy teams and patients, as new data suggests more than one in 10 people have had to visit multiple pharmacies to obtain their prescription medicines in the past year. The new statistics from AI-powered supply chain management platform 7bridges, also showed […] The post New data shows ongoing ‘burden’ of supply issues on pharmacies and patients appeared first on The Pharmacist.

88
article thumbnail

Boehringer Ingelheim India signs MoU with Maha Govt to strengthen stroke care

Express Pharma

Boehringer Ingelheim India has signed a Memorandum of Understanding (MoU) with the Public Health Department of the Government of Maharashtra. The partnership aims to enhance stroke care services in hospitals across the state through timely and quality care to patients, while further strengthening the stroke care infrastructure in the state. The MoU was signed at St George Hospital, Mumbai in the presence of dignitaries from the Maharashtra Government, World Stroke Organisation, National Programm

article thumbnail

Views sought on finances and capacity within community pharmacy

The Pharmacist

Community pharmacy owners are being urged to share their views on finances, pressures and capacity as part of a new survey launched by Community Pharmacy England. The representative body – which is formerly known as PSNC – said it will use the data gathered from the poll to inform an upcoming committee meeting and to […] The post Views sought on finances and capacity within community pharmacy appeared first on The Pharmacist.

article thumbnail

Reducing Readmission Rates for Hospitals: 5 Essential Strategies

cureatr

In 2018 (the most recent year for data), the Agency for Healthcare Research and Quality (AHRQ) reported a total of 3.8 million adult hospital readmissions within 30 days, with an average readmission rate of 14% and an average readmission cost to hospitals of $15,200.

article thumbnail

Barclay: Pharmacy First will ‘interplay’ with pressures in general practice

The Pharmacist

Using the ‘wider skills mix’ of community pharmacy and launching a national common conditions service will help to address pressures faced by staff in general practices, the health and social care secretary has suggested. Speaking exclusively to our sister title, Nursing in Practice, on Monday, Mr Barclay pointed to the incoming launch of England’s Pharmacy […] The post Barclay: Pharmacy First will ‘interplay’ with pressures in general practice appeared first on The Pharmacist.

article thumbnail

Lupin signs MoU with Maha Govt to combat cardiovascular diseases and COPD

Express Pharma

Lupin Human Welfare and Research Foundation (LHWRF), the Corporate Social Responsibility (CSR) arm of Lupin , has signed a Memorandum of Understanding (MoU) with the Government of Maharashtra to address the growing prevalence of cardiovascular diseases (CVD) and chronic obstructive pulmonary disease (COPD) in the Palghar district of Maharashtra. The partnership aims to prioritise the diagnosis and treatment of these diseases while working to reducing their long-term prevalence. “ As a leading he

80
article thumbnail

Attovia, a new California biotech, launches with plans to rethink how drugs bind their targets

BioPharma Dive

A spinout of Alamar Biosciences, Attovia Therapeutics aims to create nanobody-based drugs that could be more effective in treating autoimmune diseases and cancer.

79
article thumbnail

DCGI gives EUA for mRNA-based Omicron-specific booster vaccine from Gennova

Express Pharma

Gennova Biopharmaceuticals announced that its mRNA COVID-19 booster vaccine – GEMCOVAC-OM – against the Omicron variant of SARS-CoV-2 received emergency use authorisation (EUA) from the office of the Drugs Controller General of India (DCGI). GEMCOVAC-OM is the first booster COVID-19 vaccine developed in India against the Omicron variant. Reportedly, GEMCOVAC-OM has demonstrated robust immune responses in the phase 3 clinical trial conducted at 20 centers across 13 cities in India In Phase-

article thumbnail

Bavarian Nordic says chikungunya vaccine succeeds in late-stage study

BioPharma Dive

The shot, which the Danish company acquired from Emergent BioSolutions, spurred protective antibodies against the mosquito-borne virus in older adults.

article thumbnail

Ferring Receives FDA Approval on Scale-Up of Gene Therapy Adstiladrin

PharmExec

Company reportedly on schedule to make drug available in the second half of this year.

98
article thumbnail

New anti-coagulants may help treat sepsis and COVID-19

World Pharma News

Scientists from Trinity College Dublin have just discovered that the drug dimethylfumarate can block blood clotting during infection, offering hope that it could be used to treat a number of conditions, such a life-threatening disseminated intravascular coagulopathy (DIC), which can occur in serious infections with bacteria that lead to sepsis or in response to viral infections such as COVID-19.

71
article thumbnail

Boehringer loses bid to be shielded from Zantac litigation

pharmaphorum

Boehringer loses bid to be shielded from Zantac litigation Phil.

105
105
article thumbnail

The Inflation Reduction Act: 10 Predictions About Market Access and Drug Channels (rerun)

Drug Channels

This week, I’m rerunning some popular posts while I prepare for this Friday’s live video webinar: PBMs and the Battle Over Patient Support Funds: Accumulators, Maximizers, and Alternative Funding. Click here to see the original post from April 2023. Like it or not, the Centers for Medicare & Medicaid Services (CMS) is barreling ahead with its implementation of the Inflation Reduction Act of 2022 (IRA).

article thumbnail

How FDA’s modernization strategy could improve drug development

PhRMA

As technology continues to rapidly advance, it’s important for regulatory agencies like the U.S. Food and Drug Administration (FDA) to keep pace and adopt new technologies and approaches to support its public health mission and ultimately, better serve patients.

article thumbnail

Survey sheds light on scale of drug shortages in UK

pharmaphorum

Survey sheds light on scale of drug shortages in UK Phil.

102
102
article thumbnail

Eli Lilly to Acquire DICE Therapeutics for ~$2.4B

PharmaShots

Shots: Eli Lilly will acquire all outstanding shares of DICE for a purchase price of $48 per share in cash representing a premium of ~40% relative to DICE’s closing price in June 2023 with a total deal value of ~$2.4B. The transaction is expected to close in Q3’23 DICE will use its DELSCAPE technology platform to develop novel oral therapeutic candidates, incl. oral IL-17 inhibitors which are currently in clinical development for the treatment of chronic diseases in immunology Additi

64
article thumbnail

The World Without Disease: Live Coverage

pharmaphorum

The World Without Disease: Live Coverage Mike.

106
106