Thu.Jun 08, 2023

article thumbnail

STAT+: Study finds supplements of amino acid taurine slow aging in mice and monkeys

STAT

The first clue was blind cats. About 50 years ago, K.C. Hayes, a professor of nutrition at the Harvard School of Public Health, took on the mystery of why some cats experienced rapid deterioration of their vision. The problem, Hayes figured out, was that some brands of cat food lacked an amino acid called taurine, something cats don’t produce themselves.

Immunity 241
article thumbnail

Yes, biopharma still has a reputation problem. These leaders are looking for solutions

PharmaVoice

Negative news is breaking down the public’s perception of the biopharma industry — but leaders around the industry have some ideas to fix it.

243
243
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

BMI is starting to plateau in rich Western countries. That doesn’t mean obesity is solved

STAT

This is part of a series about new obesity drugs that are transforming patients’ lives, dividing medical experts, and spurring one of the biggest business battles in years. Read more about  The Obesity Revolution. “S oaring obesity rates.” “An alarming surge in BMI.

239
239
article thumbnail

FDA’s decentralized trials guidance leaves slate of fresh questions for industry

PharmaVoice

Recent FDA guidance aims to bolster DCT adoption but provides little clarity on the patchwork of telemedicine laws that pose an obstacle to the approach.

130
130
article thumbnail

Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

article thumbnail

STAT+: If AI invents a new medicine, who gets the patent?

STAT

Pharmaceutical and biotech companies are increasingly using artificial intelligence to discover and make drugs and therapeutics. Congress on Wednesday asked the question: Does that mean AI can be an inventor on a patent? AI models can already look for patterns in old clinical trial data, look at images of cells and quantify changes in them, or virtually test whether drug candidates will dock in a certain receptor — all with tools that aren’t that different from Excel or a calculato

article thumbnail

After years of disappointment, cancer vaccines show new promise

BioPharma Dive

Moderna presented new data at ASCO for its melanoma shot, highlighting progress with a personalized approach that’s also being pursued by BioNTech and Gritstone.

Vaccines 127

More Trending

article thumbnail

17th Edition Project Portfolio and Resource Management Excellence for Pharma

Drug Patent Watch

17th Edition Project Portfolio and Resource Management Excellence for Pharma July 11-13, 2023 | Sheraton Philadelphia University City Hotel | Philadelphia, PA Mastering Resource and Project Prioritization, Operational Excellence, and People Development… The post 17th Edition Project Portfolio and Resource Management Excellence for Pharma appeared first on DrugPatentWatch - Make Better Decisions.

105
105
article thumbnail

Opinion: Why brain decoding is not mind reading — and why that matters

STAT

Recently, my colleagues and I published a study on decoding language from brain recordings made using functional MRI. Brain decoders are being developed to help restore communication to people who have lost the ability to speak or write. Currently, most brain decoders use recordings from implanted electrodes, and are primarily intended for people with motor system disorders.

article thumbnail

DrugChatter Featured Questions

Drug Patent Watch

DrugChatter recently launched as an experimental AI chat-based business intelligence tool. Here’s some of the more interesting questions it’s been asked: Cost savings for bulk lipitor Who Invented Advil? What… The post DrugChatter Featured Questions appeared first on DrugPatentWatch - Make Better Decisions.

103
103
article thumbnail

FDA advisers recommend approval of monoclonal antibody to protect newborns and young children from RSV

STAT

A Food and Drug Administration advisory committee voted overwhelmingly on Thursday to recommend approval of a monoclonal antibody product to protect newborns and young children from RSV. The Antimicrobial Drugs Advisory Committee voted unanimously to recommend use of nirsevimab — which will be marketed as Beyfortus — in children in the first year of life.

218
218
article thumbnail

5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

article thumbnail

Deal of the week: Strive Health raises $166m to aid kidney health services

Pharmaceutical Technology

Each week, Pharmaceutical Technology’s editors select a deal that illustrates the themes driving change in our sector. The deal may not always be the largest in value, or the highest profile. But it will tell us where the leading companies are focusing their efforts, and why. This new, thematic deal coverage is driven by our underlying Disruptor data which tracks all major deals, patents, company filings, hiring patterns and social media buzz across our sectors.

103
103
article thumbnail

STAT+: Pharmalittle: FDA commish calls U.S. drug prices ‘too high’; FDA staff says Eisai and Biogen’s Alzheimer’s drug has benefits

STAT

Rise and shine, everyone, another busy day is on the way, although the smoky covering has certainly reduced the number of noisy vehicles that usually pass by at this time of the morning. Nonetheless, there is much to do. So as usual, we are firing up the trusty coffee kettle to brew a cup or three of stimulation. Our choice today is roasted coconut.

article thumbnail

Innovative CGT Catapult labs open doors

Pharma Times

Laboratory space will accelerate the development of potentially life-saving cell therapies - News - PharmaTimes

120
120
article thumbnail

AI insight at BIO, Google and Mayo Clinic’s latest effort, & $13 million for health workforce tech

STAT

You’re reading the web edition of STAT Health Tech, our guide to how tech is transforming the life sciences.  Sign up to get this newsletter  delivered in your inbox every Tuesday and Thursday.  Psychiatric medications leave many people with mental illness behind. Can AI change that?

197
197
article thumbnail

FDA grants orphan drug designation to DTx Pharma’s CMT1A therapeutic

Pharmaceutical Technology

The US Food Drug Administration (FDA) has granted orphan drug designation to DTx Pharma’s investigational DTx-1252 for the treatment of Charcot-Marie-Tooth disease Type 1A (CMT1A). DTx-1252 is a fatty acid ligand conjugated oligonucleotides (FALCON) small interfering RNA (siRNA) therapeutic which represses the PMP22 gene in Schwann cells. It induces remyelination of axons to normal levels, increases muscle coordination, agility, mass, grip and strength, and improves electrophysiological measurem

98
article thumbnail

Listen: Merck v. USA, the best of ASCO, and Leqembi at the FDA

STAT

Are drug prices protected by the Constitution? Will Medicare embrace Alzheimer’s disease treatments? And should lawyers be allowed to use thesauruses? We cover all that and more this week on “The Readout LOUD,” STAT’s biotech podcast. STAT Washington correspondent Rachel Cohrs joins us to explain Merck’s lawsuit against the federal government and why the company believes drug pricing negotiation is “tantamount to extortion.

article thumbnail

2023 Pharm Exec Top 50 Companies

PharmExec

With the sales boom from COVID-19 products now in the rear-view, a resetting is underway for those in Pharm Exec’s listing of the top biopharma producers—shifting attention to new Rx roads ahead and the steady strategies needed to navigate a bumpy business terrain.

98
article thumbnail

MPs to investigate ‘readiness’ of pharmacies in meeting future demand

The Pharmacist

An influential committee of MPs has launched an inquiry into what action must be taken to ensure the profession is ‘in the best shape’ to meet demands and future opportunities. The Health and Social Care Committee will examine the ‘readiness’ of pharmacy services to ‘capitalise on future opportunities as the way in which healthcare is […] The post MPs to investigate ‘readiness’ of pharmacies in meeting future demand appeared first on The Pharmacist.

95
article thumbnail

4DMT’s CF gene therapy posts early cues for improving patient outcomes

Pharmaceutical Technology

The use of 4D Molecular Therapeutics’ (4DMT) aerosolised gene therapy 4D-710 has improved the quality-of-life and spirometry-measured outcomes in three cystic fibrosis patients , based on early results from a Phase I/II study presented at this year’s annual meeting of the European Cystic Fibrosis Society (ECFS). While the company previously shared interim biomarker and safety data from the Phase I/II AEROW trial (NCT05248230) in November 2022, the update features further results detailing the dr

article thumbnail

Prescription costs in England up 8% in a year

The Pharmacist

The total cost of prescription items dispensed in the community in England has increased for the fourth year in a row and has risen by 8% in a year. New data published by the NHS Business Services Authority (NHSBSA) revealed that in 2022/23, some 1.18 billion prescription items were dispensed in the community at a […] The post Prescription costs in England up 8% in a year appeared first on The Pharmacist.

95
article thumbnail

Shifting to Commercialization

Pharmaceutical Commerce

Sy Pretorius, COO & president of outsourced solutions at Eversana, dives into his new role in the space, after being a veteran in the clinical development sector.

98
article thumbnail

Armed with new gene therapy tools, a biotech startup promises a better way to target muscle diseases

BioPharma Dive

Two-year-old Kate Therapeutics is launching publicly with $51 million in funding and a licensing deal with Astellas Pharma for a neuromuscular disease gene therapy.

98
article thumbnail

Linear Diagnostics develops 20-minute STI test

Pharma Times

Emergence of quick test follows recent dramatic increase in sexually transmitted infections - News - PharmaTimes

114
114
article thumbnail

Zydus announces Phase IV EVIDENCES-XI trial to generate RWE of Saroglitazar Mg in NAFLD patients with comorbidities

Express Pharma

Zydus Lifesciences announced the commencement of Phase of IV Real World Data Registry trial “EVIDENCES- XI” for Saroglitazar Magnesium in NAFLD patients with comorbidities [ClinicalTrials.gov Identifier: NCT05872269] The Phase IV EVIDENCES- XI trial will enroll approximately 1500 male and female NAFLD patients with comorbidities (obesity, type 2 diabetes mellitus, dyslipidemia or metabolic syndrome- 200 patients each).

article thumbnail

Biopharma struggling to find talent with adequate digital skills

European Pharmaceutical Review

A new report by the Association of the British Pharmaceutical Industry (ABPI) has identified the UK biopharma industry is increasingly seeking talent with artificial intelligence (AI) and data skills to maintain competitiveness as digital technology continues to drive innovation. The research highlighted trends and gaps in skills within the UK pharmaceutical industry, based on survey data from over 30 different employers.

83
article thumbnail

Corning, SGD Pharma sign JV to open new glass tubing facility

Express Pharma

Corning Incorporated and SGD Pharma announced a joint venture that includes the opening of a new glass tubing facility to expand pharma manufacturing in India and allows SGD Pharma to adopt Corning’s Velocity Vial technology platform. A company statement informed, “Combining SGD Pharma’s vial-converting expertise with Corning’s proprietary glass-coating technology, the collaboration will enhance vial quality, improve filling-line productivity, and speed the global delivery of injectable treatmen

article thumbnail

Highlights from ASCO 2023

PhRMA

Last week, I traveled to the American Society of Clinical Oncology’s (ASCO) annual meeting. It’s always an exceptional meeting where the brightest minds in oncology, including researchers, health care providers and industry stakeholders gather to learn about the latest advancements in cancer research and development (R&D).

82
article thumbnail

Merck Files Lawsuit Against Federal Government

Pharmaceutical Commerce

Pharma company claims that the IRA’s drug pricing clauses violate the First and Fifth Amendments.

article thumbnail

Novel nanofiltration method for microbial biosurfactant downstream processing

European Pharmaceutical Review

A study has reported for the first time, an innovative downstream method for mannosylerythritol lipids (MELs), were separated from the crude MEL mixture in a first stage with the other lipid derivatives (free fatty acids, mono- and diacylglycerols) removed by organic solvent nanofiltration (OSN). Based on the OSN, the novel approach for the purification of glycolipid microbial biosurfactant, uses only one solvent and reaches a 98 percent purity.

68
article thumbnail

EC grants marketing authorisation for GSK’s RSV vaccine Arexvy

Pharmaceutical Technology

The European Commission (EC) has granted marketing authorisation for GSK’s respiratory syncytial virus (RSV) vaccine, Arexvy, for adults aged 60 years and above. The vaccine is indicated for active immunisation to prevent RSV-related lower respiratory tract disease (LRTD) in older adults. Last month, Arexvy received approval from the US Food and Drug Administration (FDA ) for the same indication.

article thumbnail

Upstream Bio raises $200M in fresh funding for asthma drug

BioPharma Dive

The biotech’s experimental drug, currently in Phase 1 testing, has drawn investor attention despite a difficult funding environment for drug startups.

62
article thumbnail

Pharmacy Guild accused in Senate of using patient contact details to protest Labor dispensing changes

The Guardian - Pharmaceutical Industry

Guild says it adheres to all relevant privacy laws as medical association says patient’s personal information is ‘sacrosanct, not a plaything’ Get our morning and afternoon news emails , free app or daily news podcast The health department has expressed concern the Pharmacy Guild appears to be using patient contact details from its “Find a Pharmacy” website to campaign against 60-day medicine dispensing.

article thumbnail

Taurine may be a key to longer and healthier life

World Pharma News

A deficiency of taurine - a nutrient produced in the body and found in many foods - is a driver of aging in animals, according to a new study led by Columbia researchers and involving dozens of aging researchers around the world. The same study also found that taurine supplements can slow down the aging process in worms, mice, and monkeys and can even extend the healthy lifespans of middle-aged mice by up to 12%.

61
article thumbnail

CorMedix on track to put an end to infection misery for dialysis patients

Outsourcing Pharma

An antifungal and antimicrobial solution could put an end to the discomfort of infection that many patients with kidney disease often endure.

64
article thumbnail

Why are rates of HPV vaccination declining globally?

pharmaphorum

Why are rates of HPV vaccination declining globally? Mike.