Thu.Sep 07, 2023

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Ketamine can be transformative for people with suicidal thoughts — if they can access it

STAT

Every day, Marisa Russello was overwhelmed by suicidal thoughts. Even one negative thought might cause her to spiral. A writer working on her book manuscript, she’d be unable to change a word without questioning the entire project’s value altogether. Her depression made it hard to fall and stay asleep. She developed insomnia and took to sleeping during the day.

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‘Not all rainbows and unicorns’ — a former CEO dishes on his rocky biotech ride

PharmaVoice

Armon Sharei took his startup SQZ from a graduate project at MIT to a Big Pharma partnership worth $1B+. Despite the company’s stumbles, Sharei’s enthusiasm for biotech’s future remains.

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Not yet free from heroin’s grip, an ‘honest, funny man’ finds his way off the streets

STAT

PHILADELPHIA — Shaun Anderson hasn’t slept this late in the day in years. He still wakes up a few times throughout the night — a habit he’s developed trying to protect himself from being jumped while at his most vulnerable. This morning, however, he slept so deeply he didn’t hear his doorbell ring. He wasn’t used to even having a doorbell, or a regular place to sleep — housing is one of many things he’d lost to a decades-long battle with op

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Neuroplast spinal cord injury study milestone

Pharma Times

The trial analyses the impact of its ‘Neuro-Cells’ among patients with traumatic spinal cord injuries - News - PharmaTimes

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Group behind ProMED fires three top moderators amid strike

STAT

The organization that runs the infectious diseases surveillance system ProMED terminated at least three of the program’s top moderators on Thursday. The three were leaders of a strike that began in early August — one that is scheduled to end on Monday. Longtime moderators Marjorie Pollack and Maria Jacobs, along with associate editor Leo Liu, received notification from ISID CEO Linda MacKinnon that their consulting agreements with the International Society for Infectious Disea

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Westminster debate to spotlight 'unprecedented challenges' in community pharmacy

The Pharmacist

The ‘unprecedented challenges’ faced by community pharmacies will be spotlighted at a Westminster debate next week. Conservative MP for Waveney Peter Aldous has secured a debate at Westminster Hall on the afternoon of Thursday 14 September on the ‘future of community pharmacies’. Confirming the news, Community Pharmacy England (CPE) said this provided a ‘very good […] The post Westminster debate to spotlight 'unprecedented challenges' in community pharmacy appeared first on The P

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Pharma faces a slew of leadership shakeups

PharmaVoice

Biogen, Sanofi, Bristol Myers Squibb and more have all recently announced major executive changes.

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Opinion: What a viral study criticizing cancer screening gets very, very wrong

STAT

A recent study prompted CNN to report, “Most cancer screenings don’t ultimately give someone extra time beyond their regular lifespan.” Does that mean it’s time to dismantle the cancer screening infrastructure in the United States? Probably not. The complex math behind screening befuddled the researchers’ attempts to assess whether screening helped people live longer, leading to unsupportable conclusions.

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Ariceum doses first patient with satoreotide

Pharma Times

The treatment targets extensive stage small cell lung cancer and aims to boost therapeutic impact - News - PharmaTimes

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What could fix cancer clinical trials’ longstanding diversity problem?

STAT

There’s a diversity problem in cancer clinical trials, and few know this better than Stephanie Walker. When she was diagnosed with stage 4 metastatic breast cancer, Walker said there was no one to help her figure out the system, not even a nurse or patient navigator. “I was told, ‘Well, you’re a nurse, you know you got this, you know it all,”’ said Walker, a hospice nurse for over 40 years and a patient advocate.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Biopharma’s rapid transition to omnichannel marketing

pharmaphorum

In today’s episode, sponsored by Veeva, we’ll hear a roundtable discussion on this fascinating topic featuring Victoria Serra Gittermann, European customer experience lead at Veeva Systems and Sebastian Noel, Veeva’s director of multichannel strategy – moderating a discussion with two executives with first-hand experience leading this change: Andy Eeckhout, global head of CRM and digital solutions at Advanz Pharma and Mokhtar Elsayed, head of global go to market commercial transformation at Sano

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STAT+: In boon for scientists, U.K. strikes deal to join E.U. Horizon research program

STAT

The U.K. has reached a deal to join the E.U.’s landmark Horizon research initiative , a move that will allow British scientists and companies to win funding from and collaborate with their European peers in the $100 billion program. Researchers and business groups have been calling for such a deal for months, warning that without membership, the U.K. risked being left behind even as it aspires to cement itself as a scientific and technology powerhouse.

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New Report Provides Key Insights on 15 Years of Duchenne Patient-Reported Data

Putting Patients First Blog

New Report Provides Key Insights on 15 Years of Duchenne Patient-Reported Data September 7, 2023 By: Pat Furlong, President and CEO, Parent Project Muscular Dystrophy (PPMD) September 7 is World Duchenne Awareness Day, a time to raise awareness and inspire action to improve the lives of people living with Duchenne and Becker muscular dystrophy. The Duchenne Registry began in 2007, when a group of thought leaders in the Duchenne muscular dystrophy community began discussing the need for a new kin

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STAT+: Amazon’s chief medical officers on where the company’s health care bets are headed next

STAT

The graveyard is littered with Amazon’s bets in health care: wearables , Care , the ill-fated Haven. Out of their ashes, a new health strategy has emerged at the tech goliath. And while its leaders insist that Amazon has no grand plan for health care, a flurry of moves in the last year offer a glimpse into its ambitions at a time when they seem more cohesive than ever.

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Number of potentially addictive drugs prescribed nearly unchanged in seven years

The Pharmacist

The number of dependency forming medicines prescribed in England has decreased by just 1% since 2015 – when the All Party Parliamentary Group for Prescribed Drug Dependence was launched to address the growing problem of prescribed drug dependence. The 67 million items for dependency forming medicines prescribed in England in 2022/23 represent a 1% decrease […] The post Number of potentially addictive drugs prescribed nearly unchanged in seven years appeared first on The Pharmacist.

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Opinion: How health care systems can protect patients from sexual assault by providers

STAT

Health care providers have a sacrosanct relationship with patients. That unique position of trust also puts them in a position of power over their patients. Far too often — as exemplified by the recent case involving a New York doctor accused of drugging and assaulting his patients, or the former pediatrician facing more than 100 lawsuits by former patients — predators are able to exploit that power to sexually abuse patients.

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Funding for practice pharmacist pay rise to be given 'shortly'

The Pharmacist

The 6% uplift to the GP contract to fund pay rises for practice staff and salaried GPs in England will be applied ‘shortly’, NHS England (NHSE) has promised. In July, the Department of Health and Social Care (DHSC) announced a 6% uplift in general practice funding, intended to cover a pay uplift for salaried GPs and […] The post Funding for practice pharmacist pay rise to be given 'shortly' appeared first on The Pharmacist.

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Biotech execs vie for a share of obesity drug boom: ‘It’s the early innings’

STAT

Pharma giants Novo Nordisk and Eli Lilly might’ve led the way into a new era of obesity drugs , but they’re not going to own it, biotech executives say.  “We’re really just at the beginning of what’s going to be a very long journey in a very large market,” said Nancy Thornberry, founding CEO of Kallyope, which is developing its own competing therapies.

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Kriya, flush with funding, buys a gene therapy for NASH

BioPharma Dive

Fresh off a Series C fundraise, Kriya has acquired the privately held Tramotane Therapeutics and its preclinical candidate for the widely prevalent liver disease.

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Back to school for biotech, Biogen’s potential pivot, & Illumina’s next chapter

STAT

Are there still too many biotech companies? How do you know when you’re in a bubble? And is there a wrong way to pronounce “TIGIT”? We cover all that and more this week on “The Readout LOUD,” STAT’s biotech podcast. Josh Schimmer and Eric Schmidt, two longtime analysts teaming up at Cantor Fitzgerald, join us for a back-to-school conversation as biotech enters the busy back third of 2023.

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Government launches women’s health survey to help shape policy

The Pharmacist

Women across England are being encouraged to help shape future reproductive health policy by sharing their experiences as part of a new ‘landmark’ survey launched by the government today. The national online survey aims to gather ‘vital data’ on women’s menstrual health, contraception, pregnancy planning and menopause, which will help shape future policy on women’s health, enhance care and […] The post Government launches women’s health survey to help shape policy appeared first on The Pha

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STAT+: Pharmalittle: South Africa ‘bullied’ into one-sided Covid vaccine deals; Astellas drops Medicare price-negotiation suit

STAT

Good morning, everyone. Jason Mast here filling in for Ed. I learned today from TikTok — burgeoning hub of reliable information that it is — that you can deep-fry coffee beans instead of roasting them, to “soft and almost buttery and rich” results. You can also roast them with helium, because it conducts heat better than the air we breathe, although apparently the results are far less impressive.

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Alzheimer’s senescent cell combination therapy presents promise

European Pharmaceutical Review

A Phase I trial employing the drug dasatinib has shown promise in clearing senescent cells in Alzheimer’s. Recent drugs targeting beta-amyloid plaques have only yielded modest results, according to the study researchers. Instead, the current US study pursued cellular senescence as an alternative area of focus. The findings published in Nature Medicine described how the US Food and Drug Administration (FDA)-approved tyrosine kinase inhibitor dasatinib was used in combination with quercetin, a pla

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Veracyte and Gustave Roussy announce partnership for cancer therapies

Pharmaceutical Technology

Veracyte has announced a partnership with Gustave Roussy to support biopharmaceutical companies in expediting the development

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QA/QC & Environmental Monitoring In-Depth Focus 2023

European Pharmaceutical Review

Leveraging PAT for environmental monitoring in light of Annex 1 The pharma industry’s adaptation to Industry 4.0 has been slow, due to the extensive regulatory requirements imposed on manufacturers. However, regulatory agencies are starting to embrace movement towards more rapid/automated systems, as illustrated in the revised EU GMP Annex 1, which is due to enter into force in August.

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UK rejoins EU’s Horizon Europe science programme

Pharmaceutical Technology

The country returns to the EU’s research programme after a Brexit-related absence and questions surrounding its re-entry prospects.

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Bioprocessing & Bioproduction In-Depth Focus 2023

European Pharmaceutical Review

How breakthrough CAR-T cancer therapies could be made more widely accessible The development and regulatory approval of the first autologous CAR T-cell therapies is a huge advance for modern medicine and has been greeted with justifiable excitement. But applications of this technology are still limited, and given the time and cost constraints, more must be done to broaden access to this treatment.

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The importance of collaboration in tackling the ethical concerns of cell and gene therapy

pharmaphorum

The importance of collaboration in tackling the ethical concerns of cell and gene therapy Mike.

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Horizon Europe deal signals UK research reinvigoration

European Pharmaceutical Review

The UK has re-entered into Horizon Europe under a new agreement with the EU. This means that scientists across the UK can access the largest R&D collaboration programme globally. Researchers can apply for grants and bid to take part in projects with certainty that the UK will be participating as a fully associated member until the deal reaches its end in 2027.

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CN Bio taps into LifeNet Health to improve organ-on-a-chip assays

Outsourcing Pharma

The UK organ-on-a-chip (OOC) company CN Bio has teamed up with LifeNet Health LifeSciences to gain access to the non-profit tissue bankâs validated human cells for use in organ models for life sciences research.

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Five takeaways from the CAR-TCR cell therapy conference

pharmaphorum

Five takeaways from the CAR-TCR cell therapy conference Mike.

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Seagen partners with Nurix to create new kind of cancer drug

BioPharma Dive

The alliance, which aims to combine Seagen’s antibody expertise with Nurix’s targeted protein degradation research, comes as the larger biotech awaits its acquisition by Pfizer to close.

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Improving access to brand planning tools through modular offerings

pharmaphorum

Improving access to brand planning tools through modular offerings Mike.

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Valneva and Pfizer share positive results from phase 2 trial for Lyme disease vaccine candidate

Pharmafile

Valneva and Pfizer have announced positive paediatric and adolescent immunogenicity and safety data for their Lyme disease vaccine candidate, VLA15, when given as a booster. Results from the VLA15-221 phase 2 trial demonstrated a strong anamnestic antibody response in paediatric, adolescent and adult patients one month after booster administration. Results from the trial emphasise the […] The post Valneva and Pfizer share positive results from phase 2 trial for Lyme disease vaccine candida

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Alnylam says hypertension drug succeeded in mid-stage study

BioPharma Dive

The trial found two higher doses of Alynlam’s RNAi therapy lowered blood pressure better than placebo. But analysts say results from a different study will be more important for the drug’s future.

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