STAT

MARCH 21, 2024

In a new test of xenotransplantation, a medical team at Massachusetts General Hospital announced Thursday that, for the first time, it had transplanted a kidney from a CRISPR gene-edited pig into a living patient. Surgeons performed the milestone procedure over four hours on Saturday, March 16, without complications. As of Thursday morning, the organ recipient, a 62-year-old man named Richard Slayman, was “recovering well” and expected to be discharged soon, the hospital said in a

Hospitals 363

Hospitals 363

PharmaVoice

MARCH 21, 2024

New tools that allow researchers to separate single cells can help map the complex web of proteins that lead to disease, providing new targets for biopharma.

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STAT

MARCH 21, 2024

Early data regarding the use of GLP-1 medications like Ozempic and Wegovy to treat addiction is “very, very, exciting,” Nora Volkow, the director of the National Institute on Drug Abuse, said Thursday. But even as she expressed enthusiasm for the new drugs’ potential, Volkow criticized pharmaceutical companies for neglecting a moral imperative to develop new addiction treatments — but acknowledged that the health system more broadly doesn’t incentivize drug com

Pharmaceutical Companies 343

Pharmaceutical Companies Pharmaceutical Companies Drug Development 343

The Pharmacist

MARCH 21, 2024

Pharmacy closures are a 'worry' for patients and could 'double' if action is not taken to prevent them, community pharmacy representatives have said as they gathered outside the Houses of Parliament yesterday before meeting with MPs. Complete with a giant map to illustrate the scale of the closures in regions across England, the event marked […] The post Pharmacy closures 'could double' without action, contractors warn appeared first on The Pharmacist.

Community Pharmacies 136

Community Pharmacies 136

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

STAT

MARCH 21, 2024

CRISPR is no longer a promising but unproven technology — it is a reality. But for this powerful gene-editing tool to reach its full potential, researchers and disease advocates say they’ll have to solve a thorny problem: connecting patients suffering from devastating diseases with therapies that could help them. Experts pointed to lab-developed tests, or LDTs, as one important element that could help make this connection during a panel at the STAT Breakthrough Summit East in New Y

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pharmaphorum

MARCH 21, 2024

There is no denying that artificial intelligence (AI) has captured the imagination of innovators working across the pharmaceutical sector. The drug discovery space is no different, with myriad applications promising to revolutionise the way that researchers and sponsors approach identifying and progressing new drug candidates.

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pharmaphorum

MARCH 21, 2024

On today’s podcast, host Jonah Comstock is joined by Meri Beckwith, co-founder of Lindus Health, a next-gen CRO that includes digital therapeutics among its specialties. They talk a little bit about the often unseen difficulties of validating a digital therapeutic through a clinical trial.

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STAT

MARCH 21, 2024

The last decade has seen billions of dollars flow into digital health companies that promise to improve outcomes for the 38 million Americans living with type 2 diabetes. Their products aren’t cheap, but in the long term, they pitch to health plans and employers that these digital tools will help cut health care costs by preventing serious complications like amputation and kidney failure.

Diabetes 300

Diabetes 300

Pharma Times

MARCH 21, 2024

The globally fast-growing progressive neurological condition affects around 153,000 people in the UK

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STAT

MARCH 21, 2024

George Yancopoulos is in touch with his teenage self. After 35 years as head scientist at Regeneron Pharmaceuticals, Yancopoulos has led the development of 12 approved medicines, turning a once-fledgling company into the $100 billion global drugmaker it is today. And you can trace a straight line back to the childhood fascination with science he fostered growing up in Woodside, Queens.

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Pharmacy Management

BioPharma Dive

MARCH 21, 2024

The job cuts at the cancer drug developer will primarily impact manufacturing roles, but will touch on several other parts of the organization, the company said.

Drug Development 112

Drug Development 112

STAT

MARCH 21, 2024

As more states create dedicated boards to cap the costs of medicines, some drugmakers and their allies are pushing back with a controversial tactic — lobbying for legislation to set exemptions for so-called orphan drugs, which are used to combat rare diseases that afflict relatively small groups of patients. The efforts, which are being joined by some some lawmakers, reflect concerns that patients may lose access to these medicines if pharmaceutical companies halt sales or decide not to i

Pharmaceutical Companies 274

Pharmaceutical Companies Pharmaceutical Companies Drug Pricing 274

pharmaphorum

MARCH 21, 2024

Clasp Therapeutics has burst onto the T-cell engager (TCE) scene with $150 million in funding for a platform that aims to improve the safety of the class, which is currently gaining traction in cancer immunotherapy.

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STAT

MARCH 21, 2024

When the first biotech companies emerged to capitalize on the revolutionary genome-editing technology CRISPR, Editas Medicine seemed like the pacesetter. It locked up some of the crucial IP, and had behind it the pioneering scientist Feng Zhang of the Broad Institute as one of its founders. But now, a decade later, Editas is seen as lagging behind its peers.

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pharmaphorum

MARCH 21, 2024

The rising demand for mono-material packaging in the pharmaceutical industry due to its sustainability benefits will have a significant impact. Learn more about how this trend is shaping the future of pharmaceutical packaging.

Packaging 101

Packaging 101

STAT

MARCH 21, 2024

What happens after you close a nearly $11 billion acquisition? Well, for Prometheus Therapeutics’ former CEO Mark McKenna, there was a brief vacation. But within weeks of the company’s acquisition by Merck closing last June, he was thinking about ideas for the future. Investors were floating ideas by him. McKenna discussed possibilities with his teenagers and Prometheus’ chief scientific officer.

Immunity 265

Immunity Immunization 265

Pharmaceutical Technology

MARCH 21, 2024

Bionomics plans to meet with the FDA following positive topline data from the Phase IIb ATTUNE trial of the post-traumatic stress disorder (PTSD) drug BNC210.

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STAT

MARCH 21, 2024

The adverse childhood experience (ACE) questionnaire has become a critical part of public health. It offers physicians a screening tool to evaluate patients, gaining valuable insights into their physical and mental well-being. This information guides the implementation of preventive measures like lifestyle counseling to reduce the risk of ACE-related chronic conditions like depression, obesity, asthma, diabetes, and cancer.

Diabetes 264

Diabetes 264

Express Pharma

MARCH 21, 2024

STEERWorld announced the formation of a Strategic Advisory Board. The board will provide strategic guidance and support the company’s growth into new markets and domains, deepening STEERWorld’s role as a leader in material transformation technology in the field of pharmaceuticals, plastics, food and nutraceuticals, biomaterials and biorefining.

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STAT

MARCH 21, 2024

LONDON — Widespread genetic testing as well as the development of cutting-edge, customized genetic therapies have opened the door to treating many more inherited conditions than previously possible. A few recent cases, in which bespoke medicines were created for children with exceedingly rare mutations, have raised hopes for furthering the approach.

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pharmaphorum

MARCH 21, 2024

A partnership between Eisai and Lifenet that aims to improve insurance cover for people with early dementia has generated its first policy, part of an effort by the pharma group to develop an ‘ecosystem’ to support patients.

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STAT

MARCH 21, 2024

I am one week away from the launch of my weekly email newsletter! It’s called Adam’s Biotech Scorecard, and it’s exclusively for STAT subscribers. One catch: We need you to sign up, which you can do here. What should you expect to see in my newsletter each week? Unfiltered, uncompromising, and (hopefully) valuable insight and analysis from the intersection of Wall Street and biotech.

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European Pharmaceutical Review

MARCH 21, 2024

A new £17.9 million strategic initiative is set to support UK advanced therapy medicinal product (ATMP) clinical trials, and help the region maintain its position as a leader in clinical research. An additional four years of funding for the Advanced Therapy Treatment Centre ( ATTC ) network is available through this programme. Collaborators include the National Institute for Health and Care Research (NIHR), Innovate UK, the ATTC network and the Cell and Gene Therapy Catapult (CGT Catapult).

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STAT

MARCH 21, 2024

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hello, everyone. Damian here with yet another megaround in biotech, a preview of some hotly anticipated data, and the perils of declining revenue.

Drug Pricing 225

Drug Pricing Drug Development 225

pharmaphorum

MARCH 21, 2024

Surgeons in the US have carried out the world’s first transplant of a pig kidney into a human, a feat made possible by genetic modification of the organ and an experimental immunosuppressant drug regimen to prevent rejection. The recipient, 62-year-old Richard Slayman of Weymouth in Massachusetts, had end-stage renal disease and was dependent on dialysis.

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STAT

MARCH 21, 2024

Is there a cure for allergies? Has the FDA become too flexible? And which drugs make you muscular? We cover all that and more this week on “The Readout LOUD,” STAT’s biotech podcast. Recorded live from from the STAT Breakthrough Summit East in New York City, we discuss some event highlights, including words from CRISPR pioneer Feng Zhang and Regeneron Pharmaceuticals head scientist George Yancopoulos.

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European Pharmaceutical Review

MARCH 21, 2024

Biopharma and bioprocessing experts have proposed an approach that uses a two-tiered control strategy for rapid bioburden testing, that can beneficially, “leverage faster detection times”. It comprises of a “fast (but possibly less sensitive) test” for process monitoring which then initiates “action for a second, longer duration test which is used to confirm and quantify the presence of bioburden and identify the [ microbial ] organism.

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STAT

MARCH 21, 2024

Top of the morning to you, and a fine one it is. Although quite chilly so far, the clear, blue skies and warm sunshine are a heartening elixir for a busy day ahead. For instance, we are scheduled to have a lively discussion about weight-loss drugs. To cope, we are brewing fresh cups of stimulation. Our choice today is orange creme. As always you are invited to join us.

Diabetes 192

Diabetes 192

Express Pharma

MARCH 21, 2024

World Tuberculosis (TB) Day is marked annually on March 24, the anniversary of the discovery of the causative mycobacterium by Dr Robert Koch. The day aims to raise awareness about the devastating health, social, and economic consequences of the disease. It is one of the leading causes of death from an infectious agent, and therefore, efforts are very much needed to eradicate the infection.

Vaccines 95

Vaccines 95

Pharmaceutical Technology

MARCH 21, 2024

Merck KGaA has announced an investment of over €300m ($326.1m) to establish a new bioprocessing production centre in Daejeon, South Korea.

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Express Pharma

MARCH 21, 2024

Kanishk Jain, from Akums Drugs and Pharmaceuticals, has been chosen as the Chairman of the Confederation of Indian Industry (CII) Uttarakhand State Council for the term 2024-25. He steps into the shoes of Bipen Gupta, the outgoing Director of GB Springs. His official induction took place during the recently concluded CII State Council meeting in Dehradun.

Hospitals 95

Hospitals 95

pharmaphorum

MARCH 21, 2024

Novartis-supported multiple research project will use Seqster's data-sharing platform to support R&D and evidence-based care

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BioPharma Dive

MARCH 21, 2024

The companies aim to identify potential patients for Bayer’s precision cancer therapies and increase access to the treatments.

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Pharmaceutical Technology

MARCH 21, 2024

The EC has approved BMS' Abecma (idecabtagene vicleucel; ide-cel) to treat adults with relapsed and refractory multiple myeloma (RRMM).

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The Script

MARCH 21, 2024

What role does telemedicine play in the future of pharmaceutical work? Rx relief explains a few challenges and opportunities on the horizon.

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