Wed.Apr 17, 2024

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STAT+: Eli Lilly’s Zepbound eases obstructive sleep apnea in trials

STAT

Eli Lilly reported positive results for its obesity drug Zepbound in obstructive sleep apnea, giving the medication a new edge in the highly competitive obesity market. The results also pave the way for Zepbound to potentially become the first approved treatment for obstructive sleep apnea, or OSA, a common disorder characterized by breathing interruptions during sleep.

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3 big patent expirations in 2024 and how companies are pivoting

PharmaVoice

As the cliffs approach, pharma companies are tackling the sales hit with diverging strategies.

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Second-generation mosquito nets prevented 13 million malaria cases in large pilot programs

STAT

The fight against malaria is a test of human intelligence against mosquitoes — and so far, our minuscule winged enemy is winning. But new results shared this week show substantial improvements in one of the most important tools we have to prevent the life-threatening disease: bed nets. Results shared this week by the New Nets Project, an initiative funded by Unitaid and the Global Fund, highlighted a pair of second-generation bed nets tested in endemic areas between 2019 and 2022.

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AI in Medical Communications: Revolutionising the present, redefining the future

pharmaphorum

Discover how AI is transforming medical communications and reshaping the future of healthcare. Learn about the latest trends, technologies, and advancements in this rapidly evolving field.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Health disparities and premature deaths run deep, even in best-performing states

STAT

A new analysis of health inequities in the United States shows that every state has deep racial and ethnic disparities in the performance of their health care systems. The report released Thursday by the Commonwealth Fund analyzed 25 indicators that track health outcomes, health care access, and quality of care provided for five racial and ethnic groups.

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Reshoring the UK pharmaceutical supply chain for future resilience

pharmaphorum

Learn about the importance of reshoring the UK pharmaceutical supply chain for future resilience. Discover how this strategic move can enhance local production and secure the availability of critical medications.

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More Trending

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Sage drops dalzanemdor for Parkinson’s after trial flop

pharmaphorum

Sage Therapeutics has suffered another disappointment after deciding that it will have to drop the Parkinson’s programme for key pipeline drug dalzanemdor after it showed no benefit in a phase 2 trial. The oral positive allosteric modulator (PAM) of the NMDA receptor is being investigated to see if it can counteract mild cognitive impairment in neurodegenerative disorders, and the PRECEDENT trial in Parkinson’s is the first major readout from the drug programme.

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STAT+: Hospital price transparency rules are seeding a new crop of health tech startups

STAT

Federal rules forcing hospitals and insurers to post rates for medical procedures have taken effect, but the data’s so messy that a crop of new startups is rushing in to make a business out of parsing it for whoever is willing to pay. Silicon Valley venture funds Andreessen Horowitz and Yosemite, the cancer-focused fund launched by Steve Jobs’ son Reed Jobs , are backing the small but growing group of companies eager to sift through complex pricing data to help patients and employe

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Telehealth firm Cerebral faces $7m FTC fine over privacy

pharmaphorum

The FTC is seeking a $7 million fine on telehealth company Cerebral for violating patients' data privacy and making cancellation difficult.

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Opinion: Viral hepatitis is a silent killer. It can’t be eliminated if it isn’t tracked

STAT

Before the Covid-19 pandemic, viral hepatitis killed more people in the United States than all 60 other reportable infectious diseases combined, including HIV, pneumonia, and tuberculosis. Which doesn’t really make sense, since effective vaccines are available for hepatitis A and B, there are successful therapies for hepatitis B, and there’s a treatment that can cure hepatitis C.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Reuters Pharma Europe 2024 – Day Three

pharmaphorum

As Reuters Pharma Europe 2024 comes to a close in Barcelona, pharmaphorum remains on site to live blog the last remaining talks and insights.

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STAT+: Teladoc became a household name under Jason Gorevic. Investors wanted more

STAT

At the J.P. Morgan Healthcare Conference in January, Teladoc CEO Jason Gorevic dismissed the growing chorus of naysayers, expressing confidence in his company’s trajectory and asserting, “I think that we are probably still underappreciated with respect to our market advantage, the financial performance that we’ve demonstrated, as well as the bright outlook we have in terms of our growth potential going forward.

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Stelara biosimilar from Alvotech, Teva approved by FDA

BioPharma Dive

The companies plan to launch their copycat version of the blockbuster immune disease drug early next year, per a legal settlement with J&J.

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STAT+: The next frontier in data privacy? Your brain

STAT

Consumer neurotechnology is booming. You can buy a funky-looking headband for $500 on the internet if you want your own personal EEG to track your brain data. But before you click purchase, you might want to check out the device’s privacy policy. These consumer devices are unlikely to include any protections or restrictions around how companies can employ or sell a user’s neural data, according to a new report from the Neurorights Foundation , a nonprofit that advocates for the eth

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MaaT microbiota drug shows survival advantage in GvHD

pharmaphorum

MaaT Pharma's microbiota therapy MaaT013 shows survival benefit in acute GvHD in an early access programme, boding well for an ongoing phase 3 trial.

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Amylyx’s Relvyvrio data was, as promised, disappointing

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. So the GLP-1s strike again: Eli Lilly’s Zepbound seems to work in obstructive sleep apnea as well. Beyond that, we see up close how Amylyx’s ALS drug — which it is pulling from the market — really didn’t differ much from placebo, and see more market and investment potential for psychedelics.

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Majority of advanced credentialing candidates work in primary care

The Pharmacist

The majority of pharmacists applying to receive ‘advanced’ level credentialing from the Royal Pharmaceutical Society (RPS) work in primary care, analysis has shown. The credentialing assessment is designed to assure that pharmacists have the entry-level capabilities to deliver advanced level care to patients. Since the ‘advanced’ credentialing assessment was introduced a year ago, 39 pharmacists […] The post Majority of advanced credentialing candidates work in primary care appeared first

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STAT+: Pharmalittle: We’re reading about Lilly’s Zepbound for sleep apnea, the FDA budget, and more

STAT

Good morning, everyone, and welcome to the middle of the week. Congratulations on making it this far, and remember there are only a few more days until the weekend arrives. So keep plugging away. After all, what are the alternatives? While you ponder the possibilities, we invite you to join us for a delightful cup of stimulation. Our choice today is maple bourbon.

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GSK reveals data on novel gonorrhoea drug gepotidacin

pharmaphorum

GSK reveals data from EAGLE-1 trial of novel antibiotic gepotidacin for gonorrhoea, amid growing resistance to existing antibiotics.

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New campaign highlights role of pharmacy staff in general practice

The Pharmacist

A new video campaign has been launched to encourage patients to accept appointments with healthcare professionals other than a GP, including practice pharmacists and pharmacy technicians. The Institute of General Practice Management’s (IGPM’s) ‘Right Care, First Time’ campaign aims to reduce ‘the burden’ on GPs and explain the benefit of utilising the experience of the […] The post New campaign highlights role of pharmacy staff in general practice appeared first on The Pharmacist.

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Brexit is ‘driving NHS medicines shortages,’ says report

pharmaphorum

Drug shortages fuelled by Brexit are now the 'new normal' in the UK and worsened in 2023, says Nuffield Trust report.

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Study reveals how specific nasal cells protect against COVID-19 in paediatric patients

Pharma Times

The findings suggest why children tend to experience milder symptoms compared to older adults

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Is AI the Cure? BioPharma’s year of innovation and ethical reckoning

Outsourcing Pharma

Pharma companies need to take greater ownership to make sure data quality and governance is accomplished - and it is important to keep in mind the ethics of AI use will remain front and centre for the pharma industry.

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GLP-1 receptor agonists not linked to suicidal thoughts, PRAC concludes

The Pharmacist

Available evidence does not support a causal association between glucagon-like peptide-1 (GLP-1) receptor agonists and suicidal and self-injurious thoughts and actions, according to the European Medicine Agency (EMA)’s Pharmacovigilance Risk Assessment Committee (PRAC). This conclusion follows a review into GLP-1 receptor agonists starting in July 2023 after receiving case reports from the Icelandic medicines agency […] The post GLP-1 receptor agonists not linked to suicidal thoughts, PRAC

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Bormioli Pharma leading the way with sustainable pharmaceutical packaging

Outsourcing Pharma

Bormioli Pharma creates pharmaceutical packaging for drug stability, safety, and sustainability, partnering with global health leaders and says it stands at the forefront of sustainability.

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Technology advancement driving growth of rapid sterility testing market

European Pharmaceutical Review

A report by Market Research Future has predicted that the rapid sterility testing market will increase in value from $2.3 billion in 2023 to $4.3 billion by 2032. It is expected hold a compound annual growth rate (CAGR) of 8.20 percent between 2023 and 2032. Factors supporting expansion of the rapid sterility testing market Concerns around the safety of biological medicinal products is rising and will contribute to expansion of the sterility testing sector in the subsequent years, according to t

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ELRIG UK and SRG collaborate to advance life sciences professionals in drug discovery

Pharma Times

Both companies will facilitate career progression while advancing the life sciences industry

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Estetrol by Mithra Pharmaceuticals for Genitourinary Syndrome of Menopause (GSM): Likelihood of Approval

Pharmaceutical Technology

Estetrol is under clinical development by Mithra Pharmaceuticals and currently in Phase III for Genitourinary Syndrome of Menopause (GSM).

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MPs vote through smoking ban for future generations

The Pharmacist

A ban on smoking for future generations has made progress in Parliament with MPs voting it through last night. The House of Commons vote saw 383 MPs vote in favour and 67 MPs vote against the Tobacco and Vapes Bill. The bill will now need to pass a number of other hurdles, including a committee […] The post MPs vote through smoking ban for future generations appeared first on The Pharmacist.

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GSK's Gepotidacin shows promise as new treatment for gonorrhoea amid rising resistance

Outsourcing Pharma

GSK plc unveiled encouraging results from its pivotal Eagle-1 phase 3 trial for gepotidacin, a potential breakthrough oral antibiotic for uncomplicated urogenital gonorrhoea (GC) in adolescents and adults.

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Lexeo wins fast track designation for Friedreich’s ataxia gene therapy

Pharmaceutical Technology

LX2006 consists of adeno-associated virus (AAV) vector carrying the frataxin gene, responsible for causing Friedreich’s ataxia.

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MASH innovator drug partnerships surge over $2.5 bn in 2024YTD: GlobalData

Express Pharma

Biopharmaceutical companies are regaining interest in metabolic dysfunction-associated steatohepatitis (MASH) innovator drug development. MASH innovator drugs witnessed over $2.5 billion increase in the total value of partnership deals from 2020 to 2024 year-to-date (YTD), with more than $2 billion forged in Q1 2024 alone, reveals GlobalData. MASH, previously known as nonalcoholic steatohepatitis (NASH), is a disease characteriSed by liver inflammation and damage caused by the accumulation of

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Botanical Solutions Inc: Transforming vaccine adjuvant production with tree bark

Outsourcing Pharma

During DCAT this year, Gaston Saperi from Botanical Solutions Inc., BSI, sat down with Liza Laws, the senior editor of OSP and BPR to discuss his companyâs pioneering work in revolutionizing vaccine adjuvant production.

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Encouraging data for Roche multiple sclerosis injection

European Pharmaceutical Review

Roche’s twice-yearly, 10-minute subcutaneous injection of OCREVUS ® (ocrelizumab) has shown significant promise for patients with either with relapsing or primary progressive multiple sclerosis (RMS or PPMS). One-year data from the Phase III OCARINA II trial demonstrated a near-complete suppression of relapse activity (97.2 percent had no relapse) in patients through 48 weeks of the treatment.

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Merck appoints Dhananjay Singh as Life Science MD

Express Pharma

Merck recently announced the appointment of Dhananjay Singh as the Managing Director of Merck Life Science in India, in addition to his current position as Head of Science & Lab Solutions Commercial, India. Effective April 1, 2024, Dhananjay Singh has taken over from Sreenath NS, who is retiring after 36 years of illustrious service with Merck in India. “As an expert with 26 years with Merck, Dhananjay has been instrumental in shaping the Science and Lab Solutions Commercial business i

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