STAT

JULY 16, 2023

When the genome-editing tool CRISPR is thought of as a potential medicine, the targets that first come to mind are diseases like sickle cell or other conditions caused by particular mutations. Use CRISPR to fix that mutation, the idea goes, and you can treat the disease. But a pair of abstracts being presented Sunday at a medical conference highlight how, just a decade after CRISPR’s debut, researchers are deploying the tool at diseases with more complicated roots that go beyond genetics.

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Pharmacy Joe

JULY 16, 2023

In this episode, I’ll discuss the results of a pilot trial of sodium bicarbonate for metabolic acidosis in the ICU. Episode 835: Results of a Pilot Trial of Sodium Bicarbonate for Metabolic Acidosis in the ICU Subscribe on iTunes , Android , or Stitcher Sodium Bicarbonate is frequently given to ICU patients to correct metabolic acidosis however evidence to support this indication is lacking and sodium bicarb is not a benign intervention without risk of adverse effects.

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Inpatient 52

STAT

JULY 16, 2023

Belgian drugmaker Argenx said Monday that its antibody treatment called Vyvgart significantly delayed the progression of an autoimmune nerve disorder that causes people to lose feeling and muscle strength in the arms and legs. The positive outcome — a 61% reduction in the risk of relapse compared to a placebo — achieved the main goal of a Phase 3 clinical trial designed to demonstrate Vyvgart’s benefit for patients with chronic inflammatory demyelinating polyneuropathy, or C

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Drug Development 205

Pharmaceutical Business Review

JULY 16, 2023

This therapy is intended for use in patients with severe renal impairment including those on dialysis. The latest announcement comes after the decision from European Commission to extend the use of Veklury for the treatment of patients with Covid -19. With the updated information, renally-impaired patients are not required to undergo eGFR testing before or during treatment with Veklury.

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Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

Drug Patent Watch

JULY 16, 2023

Annual Drug Patent Expirations for XPOVIO Xpovio is a drug marketed by Karyopharm Theraps and is included in one NDA. It is available from one supplier. There are six patents… The post New patent for Karyopharm Theraps drug XPOVIO appeared first on DrugPatentWatch - Make Better Decisions.

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RX Note

JULY 16, 2023

Introduction There are few main groups of fungi infecting human. Dermatophytes : Dermatophyte skin infections are classed by anatomical location. Athlete's foot (tinea pedis) Groin infection (tinea cruris or 'jock itch') 'Ringworm' of the skin (tinea corporis) Scalp 'ringworm' (tinea capitis) - hair loss with inflammation at the affected area 'Ringworm' of the nails (tinea unguium) Malassezia yeasts Pityriasis versicolor Candida yeasts Cutaneous candidiasis Candidal vulvovaginitis Oral thrush (o

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Diabetes Immunity Immunization Community Pharmacies 52

RX Note

JULY 16, 2023

Introduction Dandruff (pityriasis capitis) is a chronic, relapsing, noninflammatory hyperproliferative skin condition, which is often seen as socially unsightly and a source of embarrassment. It is considered to be a mild form of seborrheic dermatitis, associated with an overgrowth of the yeast Malassezia furfur. Symptoms Dandruff is characterized by greyish-white flakes or scales on the scalp and an itchy scalp as a result of excessive scaling.

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Community Pharmacies 52

Drug Patent Watch

JULY 16, 2023

Annual Drug Patent Expirations for NUEDEXTA Nuedexta is a drug marketed by Avanir Pharms and is included in one NDA. It is available from two suppliers. There are two patents… The post New patent expiration for Avanir Pharms drug NUEDEXTA appeared first on DrugPatentWatch - Make Better Decisions.

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RX Note

JULY 16, 2023

Introduction Sunburn is an acute cutaneous inflammatory reaction to ultraviolet radiation (particularly UVB) from natural sunlight or artificial sources (e.g. tanning beds, phototherapy devices). Painful erythema starts 2 to 6 hours after exposure , reaching a maximum at 24 hours. In severe cases, blistering is associated with malaise, fever, nausea and vomiting.

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Mayo Clinic 52

Drug Patent Watch

JULY 16, 2023

[![darunavir structure]([link] Darunavir is the generic ingredient in two branded drugs marketed by Janssen Prods, Lupin Ltd, and Teva Pharms Usa and, and is included in four NDAs. There are… The post New tentative approval for Msn Labs drug darunavir appeared first on DrugPatentWatch - Make Better Decisions.

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Pharmacy Management

Med Ed 101

JULY 16, 2023

Sodium polystyrene sulfonate (SPS, Kayexalate) has been used for decades to help lower potassium levels and manage hyperkalemia. It does this by exchanging sodium ions for potassium ions in the gut (primarily the large intestine). The compound is then removed from the body out through the stool. It has some risks and controversy associated with […] The post Should SPS (Kayexalate) Ever Be Used?

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pharmaphorum

JULY 16, 2023

First Wave faces choppy waters with cystic fibrosis drug Phil.

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PharmaTech

JULY 16, 2023

Development of novel small molecule active pharmaceutical ingredients (APIs) is increasingly turned over to outsourced partners who have become the primary drivers of the product’s overall development and go-to-market strategy. With hundreds of potential partners that drug owners can choose from to develop and manufacture small molecule APIs, choosing the best partner can be a challenging task.

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Drug Development 40

pharmaphorum

JULY 16, 2023

Lilly bulks up in obesity with $1.93bn Versanis buy Phil.

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PharmaTech

JULY 16, 2023

You can rely on Pfizer CentreOne as your CDMO for high-quality API synthesis, from process development through long-term supply. Our capabilities include complex organic synthesis, fermentation and bioprocessing up to 150,000-liter scale, milling and micronizing, process optimization and scale-up, and process industrialization.

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PharmExec

JULY 16, 2023

Webinar Date/Time: Tue, Aug 29, 2023 10:00 AM EDT

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PharmaTech

JULY 16, 2023

Webinar Date/Time: Thursday, August 24th, 2023 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST

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PharmExec

JULY 16, 2023

Webinar Date/Time: Thu, Aug 17, 2023 10:00 AM EDT

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Drug Patent Watch

JULY 16, 2023

This chart shows the drugs with the most patents in Sweden. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.… The post Which pharmaceutical drugs have the most drug patents in Sweden? appeared first on DrugPatentWatch - Make Better Decisions.

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