STAT

MARCH 4, 2024

Having Covid-19 increases a person’s risk of developing an autoimmune disease in the year after infection, a large study out of South Korea and Japan reports, but vaccination helps decrease that risk. Researchers used the medical records of 10 million Korean and 12 million Japanese adults to see whether those who had Covid were more likely to be diagnosed with autoimmune inflammatory rheumatic diseases, or AIRDs, in the year following infection.

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Vaccines Medical Records 363

PharmaVoice

MARCH 4, 2024

In its zeal to stamp out anticompetitive practices and lower drug prices, a consultant said the FTC might have overlooked the unique considerations in rare disease drug development.

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Drug Pricing Drug Development 130

STAT

MARCH 4, 2024

As part of its battle to blunt the growing cost of medicines, the White House on Monday held a so-called listening session in hopes of finding ways to rein in big pharmacy benefit managers, which occupy an opaque but crucial role in pharmaceutical pricing in the U.S. The gathering resembled something of a fact-finding mission as a small group of policymakers and business people briefly shared their experiences dealing with the largest industry middlemen, who negotiate with drugmakers on behalf o

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PharmaVoice

MARCH 4, 2024

Why the company’s novel therapeutics could have a competitive edge in a crowded cancer indication.

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Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

STAT

MARCH 4, 2024

As a fetus develops, its body is bathed in amniotic fluid: a warm, salty soup of nutrients, hormones, and antibodies produced by its mother. And into that fluid, a fetus is constantly sloughing off or peeing out cells, which provide genetic material that doctors can pull out with a needle and examine for signs of disease in a process called amniocentesis.

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pharmaphorum

MARCH 4, 2024

Inhaled cannabinoids have been shown to perform better than placebo in providing pain relief for people suffering from acute migraine in a clinical trial

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The Pharmacist

MARCH 4, 2024

Following the Sigma Conference 2024, The Pharmacist sat down with Dr Leyla Hannbeck, chief executive of the Association of Independent Multiple Pharmacies (AIMp) to discuss how primary care can work together. How do you think AIMp members are approaching the idea of working collaboratively, with the different professions – including GPs? We've always felt this […] The post Leyla Hannbeck: We’ve got to work together as primary care appeared first on The Pharmacist.

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STAT

MARCH 4, 2024

The cyberattack on Change Healthcare has fractured the country’s health care payment infrastructure. But it also exposed how complicated and vital these electronic pipes are. Using terms like “clearinghouse” and “electronic data interchange” are quick ways to lose an audience. But Ben Handel, a health economist at the University of California, Berkeley, for the past 13 years, has become intimately familiar with that language.

Hospitals 326

Hospitals 326

BioPharma Dive

MARCH 4, 2024

The deal gives the German pharma partial rights to a closely watched medicine for transthyretin amyloidosis cardiomyopathy that analysts expect to become a multibillion-dollar product.

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STAT

MARCH 4, 2024

Akero Therapeutics said Monday that extending treatment with its experimental drug for the liver disease known as MASH from six months to two years resulted in better outcomes for patients — most notably reductions in liver scarring at a rate three times higher than placebo without worsening other symptoms. The mid-stage study of the Akero drug called efruxifermin achieved its main goal in September 2022.

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Drug Development 284

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Pharmaceutical Technology

MARCH 4, 2024

In late 2023, the Medicines and Healthcare products Regulatory Agency approved Vertex’s Casgevy, which became the inaugural clustered regularly interspaced short palindromic repeats (CRISPR)-based drug for the haematological indications beta thalassemia and sickle cell disease (SCD).

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STAT

MARCH 4, 2024

Over the last few years, virtual mental health company Talkspace has been on a relentless quest to conquer the insurance market. The next step in that journey, Medicare, may prove the most challenging yet. Talkspace’s pivot away from its direct-to-consumer roots has so far been a success. The company claims its 130 million people have access to its services through deals with  insurers, employers, or through other arrangements, and it is now knocking on the door of profitability 

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Express Pharma

MARCH 4, 2024

Attention-deficit/hyperactivity disorder (ADHD) is a clinically heterogenous neurodevelopmental disorder with high rates of comorbidity with other childhood-onset psychiatric disorders as well as learning disorders. As a result, pipeline products capable of targeting both ADHD and comorbid symptoms will have a competitive edge to capture a highly saturated ADHD market, says GlobalData.

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STAT

MARCH 4, 2024

Lack of health data on LGBTQ+ people has real-world consequences. A participant in a 2020 report from the National LGBT Cancer Network said: “There are no guidelines for cancers that are more prevalent among Trans women. I had to fight like hell to have an anoscopy, and sure enough we found [precancerous lesions]!” That same year, the National Academies of Sciences, Engineering, and Medicine issued a hallmark report  on the health and well-being of LGBTQ+ people.

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Pharmafile

MARCH 4, 2024

Johnson & Johnson have announced that the US Food and Drug Administration (FDA) has approved Rybrevant (amibantamab-vmjw) following a priority review. The drug has been approved in combination with chemotherapy (carboplatin-pemetrexed) for the first-line treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 […] The post FDA approves J&J’s Rybrevant with chemotherapy for NSCLC treatment appe

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Chemotherapy 109

STAT

MARCH 4, 2024

WASHINGTON — The first over-the-counter birth control pill  will be available in U.S. stores later this month, allowing American women and teens to purchase contraceptive medication as easily as they buy aspirin. Manufacturer Perrigo said Monday it has begun shipping the medication, Opill , to major retailers and pharmacies. A one-month supply will cost about $20 and a three-month supply will cost around $50, according to the company’s suggested retail price.

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BioPharma Dive

MARCH 4, 2024

The two pharmacy retailers will begin dispensing mifepristone in some states weeks before the start of a Supreme Court case that will decide how widely the pill can be accessed.

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STAT

MARCH 4, 2024

A commonly prescribed medication for children’s asthma is disappearing from pharmacists’ shelves, forcing parents and pediatricians to scramble for alternatives just as  allergy seaso n  is about to start. In a move unusual for such a widely used drug, GlaxoSmithKline discontinued Flovent HFA, the brand name of its corticosteroid treatment fluticasone propionate, at the end of December.

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Express Pharma

MARCH 4, 2024

Dr Mansukh Mandaviya, Union Minister for Chemicals & Fertilizers and Health & Family Welfare virtually inaugurated 27 greenfield bulk drug park projects and 13 greenfield manufacturing plants for medical devices recently. Addressing the gathering, Dr Mandaviya said, “Medicines are an essential requirement for any society. During the COVID-19 pandemic, the dangers of supply chain getting affected, the risks of being highly dependent on imports of critical resources like bulk drugs and med

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Compounding 104

STAT

MARCH 4, 2024

SOMERVILLE — At 19 months old, Lucas Guo has never crawled, walked, or stood by himself. He babbles but can’t say words. He struggles to chew and swallow. He gets most of his nutrition through a feeding tube attached to his belly. Lucas has one of the world’s rarest diseases, ZTTK syndrome, a complex neurological disorder caused by a genetic mutation.

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Documentation 224

pharmaphorum

MARCH 4, 2024

Explore the future of drug manufacturing with dark factories, robotic and automated facilities that promise efficiency and innovation. Learn how these advancements are shaping a bright future for the pharmaceutical industry.

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STAT

MARCH 4, 2024

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hello! A thought: I moved to San Diego last year and am always on the lookout for interesting news. If you’re here, reach out! In today’s newsletter, we discuss embryonic stem cell ethics, learn of parents searching for a treatment for their son’s ultra-rare neurological disease, and more.

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Drug Pricing Drug Development 217

The Pharmacist

MARCH 4, 2024

Perceptions of the safety of vaping have worsened considerably over the past decade amongst people who smoke, a UK study has found. The Cancer Research UK funded analysis has tracked survey responses since 2014 among more than 28,000 smokers in England. They found there had been an overall increase in the perceived harm of e-cigarettes […] The post Smokers’ views on harms of vaping worsened in recent years appeared first on The Pharmacist.

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STAT

MARCH 4, 2024

Next stop: Beacon Hill. Governor Maura Healey’s long-awaited plan to double down on state funding for the biotech and medical technology sector came into focus Thursday with the announcement she’ll seek $1 billion over the next decade to reauthorize the state’s 16-year-old life sciences initiative. But lawmakers so far are noncommittal on funding the plan.

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pharmaphorum

MARCH 4, 2024

The clock has started ticking in the EU on two marketing applications for AstraZeneca and Daiichi Sankyo’s TROP2-targeting antibody-drug conjugate datopotamab deruxtecan in breast and lung cancer. The EMA has validated the two parallel applications for the drug, also known as Dato-DXd, in adults with previously treated non-small cell lung cancer (NSCLC) and hormone receptor-positive, HER2-negative breast cancer.

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STAT

MARCH 4, 2024

Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and invigorating, because that oh-so familiar routine of online meetings, phone calls, and deadlines has predictably returned. But what can you do? The world, such as it is, continues to spin. So time to give it a nudge in a better direction with a cup of stimulation.

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Drug Pricing Labelling 204

Pharmaceutical Technology

MARCH 4, 2024

The EMA has validated the jointly developed TROP2-directed therapy for patients with breast or lung cancer following positive Phase III data.

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European Pharmaceutical Review

MARCH 4, 2024

As a cornerstone of advanced therapeutics in modern medicine, biologics command significant attention in the search for effective treatments for human diseases. These biopharmaceuticals encompass a range of products including vaccines, recombinant therapeutic proteins, tissues, cells and gene therapies – all sourced from living organisms. 1 However, the entry of biologics into the pharmaceutical market is not without unique challenges, particularly when compared to small molecule drugs.

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Vaccines Immunity Immunization Compounding 90

Pharma Times

MARCH 4, 2024

Around 900,000 people in the UK are affected by the progressive neurodegenerative disease

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Express Pharma

MARCH 4, 2024

FLAME University hosted the annual conference of the Indian Drugs Manufacturers’ Association (IDMA) – vriddhi 2024, in association with Bain & Company on February 23-24. Held on its campus in Pune, the two-day conference welcomed over 40 business leaders, 50 organisations, investors, and policymakers, convening for a national summit. The agenda of this event was to examine and assess the opportunities, challenges, and strategic directions of the Indian pharma industry.

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Pharma Times

MARCH 4, 2024

In the UK alone, the aggressive form of cancer affects around 52,000 men every year

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European Pharmaceutical Review

MARCH 4, 2024

According to new data in older and heavier children treated with Novartis’ spinal muscular atrophy (SMA) gene therapy, nearly all participants in the Phase IIIb trial maintained or improved motor milestones after 52 weeks. Final data from the Phase IIIb SMART study of Zolgensma ® (onasemnogene abeparvovec) highlighted its safety and efficacy in children weighing ≥ 8.5kg to ≤ 21kg, with a mean age of 4.69 years.

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Labelling 80

World Pharma News

MARCH 4, 2024

Novartis today presented new data that continue to support the clinical benefits of Zolgensma® (onasemnogene abeparvovec), the only one-time gene therapy for the treatment of spinal muscular atrophy (SMA). Final data from the SMART study highlight the safety and efficacy profile of Zolgensma in children with SMA weighing ≥ 8.5 kg to ≤ 21 kg, with a mean age of 4.69 years, most of whom (21/24, 87.5%) had discontinued use of another disease modifying therapy at the time of treatment.

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pharmaphorum

MARCH 4, 2024

Bayer licenses European rights to BridgeBio's acoramidis, putting some big pharma muscle behind the ATTR cardiomyopathy treatment

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The Pharmacist

MARCH 4, 2024

Antimicrobials are being managed ‘appropriately’ under Pharmacy First, NHS England (NHSE)’s Head of Delivery for Community Pharmacy Clinical Strategy has told general practitioners. Pallavi Dawda also revealed that, as of mid-last month, community pharmacies in England had delivered 32,000 Pharmacy First consultations. And she told GPs concerned about patients being ‘bounced back’ to general practice […] The post NHSE: Pharmacists are ‘managing antimicrobials appropriately’ appeared first

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Community Pharmacies 82