Tue.Mar 12, 2024

article thumbnail

Opinion: No parent who has seen the children I’ve treated for measles would refuse a vaccine

STAT

Over the past year, I have watched many children die of measles. In the final stages, little lungs, filled with fluid and racked with inflammation, struggle for oxygen. The victims breathe faster and faster, gasping for air until, exhausted, they stop.

Vaccines 364
article thumbnail

As colorectal deaths rise among younger people, a screening tool could help pinpoint more patients

PharmaVoice

As colorectal deaths rise among younger people, a diagnostic could help pinpoint more patients.

246
246
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Rigid rules at methadone clinics are jeopardizing patients’ path to recovery from opioid addiction

STAT

DETROIT — Every morning, Rebecca Smith, nursing a surgically repaired knee, carefully walks down the hallway of her brutalist brick apartment building, takes the elevator one floor to the lobby, and negotiates the sharply angled driveway outside. There, she waits for an Uber to take her to the last place she wants to go: her methadone clinic.

363
363
article thumbnail

The silver lining around Lilly’s Alzheimer’s delay could be a future with better drugs

PharmaVoice

Although a regulatory delay for Eli Lilly’s donanemab in Alzheimer’s disease is a competitive setback, researchers have their eye on better drug development as a result.

article thumbnail

Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

article thumbnail

After Amylyx ALS trial failure, patients share disappointment and fear — but some hope

STAT

The news last week that a Phase 3 trial of Amylyx Pharmaceuticals’ amyotrophic lateral sclerosis drug — marketed as Relyvrio — failed to benefit patients compared to placebo hit the ALS patient community hard. An earlier study had shown that patients who took the drug for six months experienced significantly less decline than people on the placebo in physical function, such as the ability to speak, use utensils, or climb stairs.

article thumbnail

Mahendra Patel: 'Let’s have the difficult conversations'

The Pharmacist

Working together with other healthcare professions will be crucial to embedding community pharmacy within the future of the NHS, pharmacist and academic Dr Mahendra Patel has told The Pharmacist. And the new cross-sector Independent Pharmacy Professional Leadership Advisory Board is an opportunity for community pharmacy to have an ‘equal voice’ in ‘difficult conversations’ that set […] The post Mahendra Patel: 'Let’s have the difficult conversations' appeared first on The Pharmac

More Trending

article thumbnail

Why gut bacteria is the next frontier in medicine

pharmaphorum

Discover why gut bacteria are considered the next frontier in medicine in this informative article. Learn about the importance of the microbiome, its impact on health, and how it relates to conditions like Clostridiales difficile.

120
120
article thumbnail

STAT+: First medicine developed to treat MASH expected to be approved soon

STAT

The Food and Drug Administration is expected to approve the first medicine developed specifically to treat the serious liver disease known as MASH as soon as this week. The pill, called resmetirom, is made by Madrigal Pharmaceuticals. Metabolic dysfunction-associated steatohepatitis, or MASH and previously called NASH , is often associated with obesity.

270
270
article thumbnail

After surprise trial failure, ALS doctors brace for one less treatment option

BioPharma Dive

Physicians are preparing for tough conversations with patients on Amylyx Pharmaceuticals’ drug, Relyvrio, while holding out hope it still may help some with the disease.

120
120
article thumbnail

Delta 8 THC use reported by 11% of high school seniors

STAT

WASHINGTON — In the last year, an estimated 11% of high school seniors have used Delta 8 THC, according to a new report published Tuesday in the Journal of the American Medical Association. Delta 8 THC is a quasi-legal psychoactive version of cannabis, which has skyrocketed in popularity after a loophole found in a 2018 federal law allowed it to be sold nationwide without the same restrictions placed on traditional marijuana.

266
266
article thumbnail

5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

article thumbnail

Pharmacy ear care pilot sees third of patients within a week

The Pharmacist

A pilot using community pharmacies to deliver comprehensive ear care has improved patient waiting times and accessibility and has empowered pharmacy teams. But to make such a service sustainable, the fee paid to community pharmacies must be ‘realistic and viable’, an evaluation of the pilot has warned. And with the pilot due to end this […] The post Pharmacy ear care pilot sees third of patients within a week appeared first on The Pharmacist.

article thumbnail

STAT+: For-profit health system’s Mass. hospitals teetering on the brink of financial disaster

STAT

Steward Health Care’s Massachusetts hospitals are on the brink of financial disaster. But in many important ways, Steward’s troubles are just a symptom of a larger crisis engulfing the entire industry. While Steward’s for-profit ownership structure put its hospitals at a disadvantage, many health care executives say the state’s entire network of hospitals  is approaching a capacity shortage  not seen since the early days of the Covid-19 pandemic.

Hospitals 243
article thumbnail

ICBs urged to consider health inequalities when reducing OTC prescribing

The Pharmacist

Guidance released today by NHS England (NHSE) has called for community pharmacists to play a role in reducing prescribing of over the counter (OTC) items for minor and self-limiting conditions. Though it acknowledged that some patients ‘may not be able to self-care’ for reasons including ‘medical, mental health or social vulnerability’. It therefore recommended integrated […] The post ICBs urged to consider health inequalities when reducing OTC prescribing appeared first on The Pharmacist.

104
104
article thumbnail

STAT+: Pharmalittle: We’re reading about a failed schizophrenia drug trial, a Pfizer cancer drug, and more

STAT

Top of the morning to you, and a fine one it is. Sunny skies and a crisp breeze are wafting over the Pharmalot campus, where the official mascots are roaming about in search of noshes and amusement. This marks a welcome change from the unusual high winds the day before. So we have decided to celebrate by firing up the coffee kettle to brew another cup of stimulation.

205
205
article thumbnail

Older Adults’ Experience with Opioid Use, Deprescribing

Pharmaceutical Commerce

A qualitative study explores how these drugs are impacting these patients’ lives, while digging deeper into the possibility of deprescribing, with insight from primary care physicians.

111
111
article thumbnail

When did Wall Street sour on Lilly’s Alzheimer’s drug?

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning, everyone. Damian here with news that STAT+, our exclusive source for trusted and authoritative coverage of the life sciences, is on sale this week. Claim your exclusive offer now  and save 40% with code STAT40.

article thumbnail

Avoiding the data swamp: The transformative power of AI

pharmaphorum

In the latest episode of the pharmaphorum podcast, host Nicole Raleigh speaks (virtually) with Nathan Clark, founder and CEO of Ganymede, a modern data platform and Cloud infrastructure for science, to discuss the evolving role of the Cloud in biopharma and some rather revolutionary tools in AI drug discovery.

109
109
article thumbnail

Uniform Code for Pharmaceutical Marketing Practices 2024 rolled out

Express Pharma

The Government has rolled out the Uniform Code for Pharmaceutical Marketing Practices (UCPMP) 2024. This initiative, spearheaded by the Ministry of Chemicals and Fertilizers, seeks to curb misleading promotional activities and ensure responsible marketing practices within the sector. Some key features of UCPMP 2024 are: Ethical promotion: The UCPMP mandates that drug promotion must adhere to stringent ethical criteria.

Hospitals 109
article thumbnail

Changing Faces: Agency, consultancy, and investor hires from February 2024

pharmaphorum

Discover the latest agency, consultancy, and investor hires from February 2024, including personnel from OVID Health, Avalere, WE Communications, and Eurozeo. Stay updated with industry movements and key players.

article thumbnail

Adopting New Manufacturing Technologies

Pharmaceutical Commerce

A sit-down with Groovy Singh, CEO of Bright Green Corporation, who describes the waves in the global supply chain the company is making after being authorized to grow cannabis, along with cannabis-related products.

105
105
article thumbnail

Software Advances Mass Customization for Cell and Gene Therapies

PharmaTech

In an interview, Fabian Gerlinghaus of Cellares outlines a paradigm change in both hardware and software, regulatory expansions, and some positive cost outcomes for the CGT field.

98
article thumbnail

Pfizer’s Velsipity heading for NHS use in ulcerative colitis

pharmaphorum

Up to 25,000 patients in England with ulcerative colitis are eligible for treatment with Pfizer’s Velsipity after NICE backed use of the drug on the same day as its MHRA approval.

98
article thumbnail

DOP amends PTUAS, expands eligibility criteria to include MSMEs

Express Pharma

The Department of Pharmaceuticals (DoP) has announced a comprehensive overhaul of the Pharmaceutical Technology Upgradation Assistance Scheme (PTUAS) sub-scheme. PTUAS is a credit linked scheme which provides financial support of up to one crore to a pharma MSME aspiring to upgrade its manufacturing facility as per WHO-GMP standards or Schedule M standards.

article thumbnail

ICR awarded $25m by Cancer Grand Challenges to research solid tumours in children

Pharma Times

Globally, cancer is currently the most leading cause of death due to disease among children

125
125
article thumbnail

Angelini Pharma partners with Wazoku to improve target identification in epilepsy

Outsourcing Pharma

International pharmaceutical firm Angelini Pharma has initiated a creative crowdsourcing campaign aimed at enhancing target identification in epilepsy, particularly focusing on drug-resistant phenotypes.

94
article thumbnail

Biotech funding set for recovery in 2024: GlobalData

Express Pharma

The biopharma industry is witnessing a shift in investor sentiment. Despite facing challenges such as declining venture financing and macroeconomic pressures, there exists optimism about a recovery in biotech funding. Healthcare professionals globally express cautious optimism, emphasising the importance of alternative funding avenues and industry partnerships.

96
article thumbnail

Review calls for action on bias with medical devices

pharmaphorum

Healthcare systems need to address the impact of racial and ethnic biases in the design and use of medical devices, says an independent UK review.

103
103
article thumbnail

Data integrity considerations in Pharma and Life Sciences

European Pharmaceutical Review

Data integrity is the term used to describe the accuracy, consistency and reliability of data throughout its lifecycle. In the pharmaceutical/life sciences industries, maintaining data integrity is crucial given its role in making critical decisions that shape outcomes from drug development to human health. What are three current key trends in data integrity?

article thumbnail

Emcure Pharma forays into OTC market with Galact supplement for breastfeeding mothers

Express Pharma

Emcure Pharmaceuticals announced its entry into the over-the-counter (OTC) market, with their product Galact. Prescribed by healthcare professionals for more than 20 years, Galact will now also be available as an OTC offering. A company statement informed, “Enriched with the potency of Shatavari and six other herbs, Galact is meticulously formulated to boost breast milk production for mothers.

article thumbnail

Drug discovery and global player, Cresset, moves team into Boston marking major turning point

Outsourcing Pharma

Greater integration is to take place between the US and UK following an expansion says Cresset, a provider of integrated in-silico solutions for drug discovery.

94
article thumbnail

NHS campaign urges over 900,000 young adults to catch up on missed MMR vaccine

Pharma Times

Between October 2023 and March 2024, the UKHSA said that 733 cases of measles were reported in England

Vaccines 110
article thumbnail

Flu vaccination programme moved to October to ‘maximise’ protection

The Pharmacist

The flu vaccination programme in England has been moved from September to October this year in order to maximise vaccine effectiveness. Based on advice from the Joint Committee on Vaccination and Immunisation (JCVI), the government has asked community pharmacies to deliver most flu vaccines from October, with an exact start date to be confirmed by […] The post Flu vaccination programme moved to October to ‘maximise’ protection appeared first on The Pharmacist.

article thumbnail

Terns scores FDA orphan designation for CML therapy

Pharmaceutical Technology

TERN-701 is a BCR-ABL tyrosine-kinase inhibitor being studied in a Phase I study, with data expected in H2 this year.

105
105
article thumbnail

AAD: Sanofi showcases data on possible Dupixent successor

pharmaphorum

Sanofi says OX40L inhibitor amlitelimab could be a ‘best-in-class’ maintenance therapy for atopic dermatitis after reporting new phase 2b data

93
article thumbnail

Inlet air conveyor optimisation in a continuous tablet coater

European Pharmaceutical Review

Coating is the oldest and last key unit operation in many tablet production processes. The function of the coating ranges from purely cosmetic improvements (brand recognition, better patient acceptance using API taste masking) to alterations of tablet release characteristics (control of the release profile and bioavailability of the API). Generally, the goal of coating is to generate a thin solid layer around the tablet core.

Dosage 81