Thu.Aug 31, 2023

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No longer brushed off: A Minnesota clinic tries to rewrite medicine’s approach to miscarriage

STAT

WOODBURY, Minn. — By the time Taylor Teske came to be sitting on an exam table in an obstetrician’s office in Minnesota, her medical records marked a devastating journey: nine pregnancies, one baby, eight miscarriages. The first miscarriage happened in June 2018, almost as soon as she found out she was pregnant. Teske told her boss at the vascular clinic where she worked that she was pregnant, and he asked if she wanted to sneak a look using the clinic’s ultrasound.

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Lawmakers are already gunning for more dramatic drug pricing reforms

PharmaVoice

Medicare just announced its first-ever drug price negotiations and legislators are quickly pushing to broaden the program.

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Opinion: It’s long past time for a more comprehensive Covid treatment approach

STAT

Because Covid cases and hospitalizations are no longer front-page news, many Americans might be surprised to learn that we are in the midst of a mini-surge. The latest data from the Centers for Disease Control and Prevention, from Aug. 12, confirm a 21.6% increase in Covid-19 hospitalizations from the prior week and a 21.4% increase in Covid-related deaths, demonstrating that Covid is not over and that Latinos and Blacks have reason to be concerned.

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Antidote dispensing drones get government funding

The Pharmacist

Antidote dispensing drones or artificial intelligence that detects an overdose could be used to prevent drugs deaths, as a result of government funding awarded to 12 technology projects. The projects are the winners of the Reducing Drug Deaths Innovation Challenge, funded by the Office for Life Sciences and support the government’s Addiction Mission.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Departing Stanford president retracts two widely cited papers, against lead author’s wishes

STAT

After an expansive investigation found manipulated data and other issues with papers co-authored by Stanford’s now ex-president Marc Tessier-Lavigne , the prominent neuroscientist on Thursday retracted two studies published in the journal Science in 2001 — over the objection of a former postdoctoral researcher who played a leading role in both projects.

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Sanofi appoints a venture investor to R&D head as executive team expands

BioPharma Dive

Houman Ashrafian, currently a scientific advisor at SV Health Investors, will fill the role left by John Reed, who oversaw the transformation of research and development during his five years at Sanofi.

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BenevolentAI doses participants in BEN-8744 study

Pharma Times

The candidate is a peripherally restricted small-molecule PDE10 inhibitor to treat ulcerative colitis - News - PharmaTimes

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A big insurer decides to cover naloxone for overdose; will others follow?

STAT

At long last, naloxone is available over the counter.  But now comes a moment of truth for the overdose-reversal medication: Will increased access help to save lives? And more immediately, can everyone who wants to buy naloxone at a pharmacy afford it?

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Stem cell therapy delivers potential for sickle cell disease

European Pharmaceutical Review

New research published in the New England Journal of Medicine has indicated that stem cell gene therapy could provide a curative treatment for sickle cell disease (SCD). Based on new data from the Novartis Phase I/II clinical trial , which used the first therapy to target a new genetic area and use cryopreserved stem cells, trial participants reported a decrease in vaso-occlusive events.

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STAT+: Drug firms test medicines to halt Alzheimer’s before symptoms appear

STAT

Alzheimer’s disease has killed at least three women in Astrida Schaeffer’s family over two generations, leaving her feeling helpless and bereft. The first was her Polish-born maternal grandmother, who began showing symptoms when Schaeffer started college in 1981 and died seven years later. Then came her mother, a onetime Fulbright Scholar and high school language teacher who had been fluent in five languages but lost the ability to speak.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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UCB announces approval of Bimzelx

Pharma Times

The therapy is used to treat patients with psoriatic arthritis and axial spondyloarthritis - News - PharmaTimes

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STAT+: Pharmalittle: U.S. pharma layoffs continue to climb; senators push insulin makers for details of low-cost programs

STAT

Top of the morning to you, and a fine one it is. Blue skies and cool breezes are enveloping the Pharmalot campus, where the official mascots are bounding about the grounds and the usual street noise has dropped to a dull hum. As for us, we are immersed in the usual ritual — brewing cups of stimulation. Our choice today is the flavorful chocolate raspberry.

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Sage, reeling from depression drug decision, to lay off 40% of workforce

BioPharma Dive

Two founding executives are leaving Sage alongside a major restructuring announced weeks after the FDA approved the medicine, Zurzuvae, for much narrower use than the company had hoped.

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Lawmakers call on FDA to issue stricter bone graft guidance

STAT

You’re reading the web edition of STAT Health Tech, our guide to how tech is transforming the life sciences.  Sign up to get this newsletter  delivered in your inbox every Tuesday and Thursday.

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Cybersecurity dominates pharma industry discussions during Q2 2023: GlobalData

Express Pharma

Amid the push for digital transformation, the pharma industry finds itself navigating a critical intersection of concerns—data protection, regulations, and the threat of data breaches. This pivotal juncture has thrust cybersecurity into the spotlight in the discussions of companies during Q2 2023, revealing its paramount significance in safeguarding sensitive information, with regulation mentions getting on par with data protection, reveals the Company Filing Analytics Database of GlobalData.

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Amit Etkin: the former Stanford professor pioneering a new treatment for depression

Outsourcing Pharma

More people are talking about mental illness than ever before. However, despite increased awareness, it remains one of the most neglected areas of public health globally, with research and quality of care lagging behind physical health conditions.

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BioNTech to lead $2 bn mRNA-based oncology therapy market despite challenges: GlobalData

Express Pharma

With the rise of mRNA-based treatments, the field of oncology is about to go through a big change. The global market for mRNA-based oncology therapies is expected to reach a record-breaking $2 billion by 2029. BioNTech, a German pharma company, is expected to lead the market with projected sales of $885 million and a 44.6 per cent share by 2029, according to GlobalData.

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Vax changes welcome but communication ‘chaos’

The Pharmacist

Community pharmacy leaders have welcomed the government’s decision to start the flu and Covid vaccination programmes earlier and increase the funding for the service. But the last-minute ‘chaos’ will put additional pressure on pharmacy teams and lead to confusion for patients, one leader told The Pharmacist. Yesterday the government announced that it would be bringing […] The post Vax changes welcome but communication ‘chaos’ appeared first on The Pharmacist.

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China’s CanSino seeks more vaccine contracts after AstraZenca deal

Express Pharma

CanSino begun researching mRNA technology in 2018 and has built a facility in Shanghai that can produce up to 200 million doses a year China’s CanSino Biologics , which recently announced a contract manufacturing deal to support AstraZenca’s messenger RNA (mRNA) technology vaccine programme, is in talks with more firms on similar deals, its CEO said, as it seeks new revenue streams to make up for plummeting COVID vaccine demand.

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Focus on practice pharmacy roles ‘marked contrast’ to community

The Pharmacist

Community pharmacy leaders have raised concerns about the impact of increasing pharmacist roles in general practice on the community pharmacist workforce. Figures released this month show that the number of advanced pharmacist practitioner roles in general practice in England has nearly doubled in the last year, while the number of pharmacists has remained consistent.

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Zydus gets US FDA approval for Isotretinoin Capsules USP, 10 mg, 20 mg 30 mg and 40 mg

Express Pharma

Zydus Lifesciences has received final approval from the United States Food and Drug Administration (USFDA) for Isotretinoin Capsules USP, 10 mg, 20 mg 30 mg and 40 mg (RLD: Accutane Capsules, 10 mg, 20 mg and 40 mg: RS: Claravis 10 mg, 20 mg, 30 mg and 40 mg). Isotretinoin Capsules is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (such as benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth).

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Novo Nordisk acquires Embark and lead asset metabolic programme

Pharmaceutical Technology

Novo Nordisk has acquired Embark Biotech and its lead asset targeting obesity and other cardiometabolic diseases.

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The BioInnovation Institute welcomes eight new companies to its Venture Lab program

Outsourcing Pharma

Eight new companies have joined The BioInnovation Instituteâs (BIIâs) Venture Lab acceleration program for early-stage companies, it was announced today (August 31).

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Meeting rising demands of a new radiotheranostic era

European Pharmaceutical Review

Cancer patients critically depend on accurate diagnosis and disease treatment. Medical researchers constantly develop innovative therapies and treatment options to improve survival and quality of life. In precision oncology, technological advances have made targeted radiotheranostics a promising option for diagnosing and treating solid tumours. Usually consisting of an injected medical radionuclide and a target molecule, radiopharmaceuticals precisely bind to tumours, destroying tumour cells wit

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Metaverse or Virtual Reality? What is the Difference?

Pulses

By: Carley Jans, Ph.D Candidate, Cherie Lucas, Ph.D., BPharm, Grad Cert Edu Stud (Higher Educ), MPS, and Tracy Levett-Jones, Ph.D. The use of virtual platforms in healthcare education has evolved over the past several decades and included such terms as augmented reality, virtual reality, mixed reality, and, more recently, Metaverse. A recent Pulses post has indicated the confusion surrounding these platforms, what they involve, and how they are implemented.

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Curbing AMR through sustainable antibiotic manufacturing

European Pharmaceutical Review

[pharmaceutical companies] must take measures to manage antibiotic waste across the manufacturing supply chain” 2023 has so far, delivered a spectrum of change for antibiotic manufacturers across the pharmaceutical industry, from supply chain issues through to regulatory opportunities. A recent report by the Access to Medicine Foundation has highlighted the management of waste and steps that pharmaceutical manufacturers of antibiotics can take to limit the risk of antimicrobial resistance

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Pfizer and BioNTech Get Positive Opinion in Europe for Omicron XBB.1.5-adapted COVID-19 Vaccine

PharmaTech

The updated vaccine will be ready to ship following a positive European Commission review.

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How Unique Immune Cells can Recognize - and destroy - Tumors

World Pharma News

Gamma delta T cells, a special type of cell in the immune system, are incredibly effective at recognizing and killing cancer cells. Cancer patients with higher levels of these T cells in their tumors tend to fare better than those with lower levels. But scientists have struggled to understand exactly how gamma delta T cells can recognize cancerous cells, and how new cancer therapies may be able to take advantage of these powerful immune cells.

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Biden's Inflation Reduction Act continues to rattle big pharma as ten targeted drugs revealed

Outsourcing Pharma

The moment that major pharma companies have been dreading, since the approval of Biden's Inflation Reduction Act, has arrived.

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Express Pharma September 2023

Express Pharma

Making India An Epicentre For FR&D Click to download: September 2023 Digital Magazine The post Express Pharma September 2023 appeared first on Express Pharma.

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‘We’re in the 1999 of the internet era’: a16z’s Julie Yoo on fintech’s potential and the digital health market

BioPharma Dive

Yoo, who leads health tech investment at venture capital firm Andreessen Horowitz, outlined her fintech investment thesis and why the healthcare industry is at an inflection point.

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How the UK can compete with the US in biotech: Focus on the tech

pharmaphorum

How the UK can compete with the US in biotech: Focus on the tech Nicole.

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Expert Speak | Dr Anand Swaroop, President, Cepham Inc with Vishrut Srivastava, Managing Director, Yodaplus, India

Express Pharma

Express Pharma – Nutrify Today Boardroom series offers a platform for meaningful dialogues on the vast ocean of opportunities for the Indian pharma sector to be reaped in nutraceuticals, provided the right course is set for long and sustainable growth. In an unrestrained dialogue, Dr Anand Swaroop, President, Cepham Inc, a well-known nutraceutical ingredients developer and branded formulations owner in the US, engages with Vishrut Srivastava, Managing Director, Yodaplus, India, an experienced AI

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CN Bio introduces Dr Tomasz Kostrzewski as new chief scientific officer

Pharmafile

On 30August 2023, CN Bio announced the appointment of Dr Tomasz Kostrzewski as chief scientific officer (CSO) – a new position in the company’s leadership team. CN Bio is an Organ-on-a-Chip (OOC) biopharmaceutical company that specialises in designing and manufacturing microphysiological systems. Dr Kostrzewski originally joined the company in 2015 and was appointed to director […] The post CN Bio introduces Dr Tomasz Kostrzewski as new chief scientific officer appeared first on Phar

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Expert Speak | Sanjaya Mariwala, Executive Chairman and Managing Director, OmniActive Health Technologies

Express Pharma

Express Pharma – Nutrify Today Boardroom series offers a platform for meaningful dialogues on the vast ocean of opportunities for the Indian pharma sector to be reaped in nutraceuticals, provided the right course is set for long and sustainable growth. In a free-wheeling video interaction with Express Pharma, Sanjaya Mariwala, Executive Chairman and Managing Director, OmniActive Health Technologies, speaks on how new-age technologies are leveraging India’s traditional medicine knowledge, e