Tue.Aug 15, 2023

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Radiation, a mainstay of cancer treatment, begins a fade-out

STAT

Every year, doctors get better tools to fight cancer. Engineered cancer-killing cells, immunotherapies, targeted drugs, and more are helping clinicians cure more patients. Increasingly, though, oncologists are trying to use less radiation, long one of the main pillars of cancer therapy. In some cases, they are even keeping certain patients with low-risk tumors off radiation entirely.

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Demand for weight loss drugs soars to nearly half of Americans

PharmaVoice

Drugs like the buzzy Ozempic are high on consumers’ radar — but lofty barriers to access remain.

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STAT+: BMS, looking to build a market for a heart drug, turns to a Viz.ai algorithm to detect disease

STAT

As Bristol Myers Squibb works to build its treatment for a heart condition that can cause difficulty breathing into a blockbuster drug, it’s propped up an algorithm designed to help find more people who are affected. The algorithm, called Viz HCM and developed by Viz.ai, earlier this month received clearance from the Food and Drug Administration.

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Woman of the Week: Novartis’ Christy Siegel

PharmaVoice

The oncology portfolio general manager for breast and women’s cancers, discusses the company’s recent “landmark” trial and how her family’s history connects her to patients.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Patient advocates warn FDA proposal on salt intake could do fatal harm to people with kidney disease

STAT

WASHINGTON — Patient advocates are warning that a recent proposal from the Food and Drug Administration meant to reduce consumers’ salt intake could inadvertently kill those with kidney disease, particularly Black Americans. The proposal at issue, which is still in draft form , was unveiled by the FDA in April. It would allow the use of salt substitutes in foods that have so-called standards of identity, regulations governing what ingredients must go in popular foods, like ketchup,

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Radiopharmaceuticals for cancer: Making radiation precise

BioPharma Dive

More than a dozen startups have joined a few publicly traded biotechs and larger pharmaceutical firms in what’s become one of the most competitive areas in drug research.

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Chancellor and former health secretary protests local pharmacy closure

The Pharmacist

The Chancellor of the Exchequer, Jeremy Hunt, has joined local Surrey residents in protesting the potential closure of a local Boots pharmacy. Mr Hunt, who was the Secretary of State for Health and Social Care between 2012 and 2018, has added his name to two local petitions against the potential closure of a Boots pharmacy […] The post Chancellor and former health secretary protests local pharmacy closure appeared first on The Pharmacist.

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STAT+: From drug shortages to high prices, U.S. system’s shortcomings have deep roots

STAT

American medicine is a tragic paradox. An example: Cancer patients are likely dying as a result of drug shortages that occurred partly because generic chemotherapies have been allowed to become too cheap. At the same time, other patients are suffering, and perhaps dying, because the financial burden brought on by the expensive medicines they need is too high.

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Unsuccessful Regulatory Filings for Biosimilar Approval: A Comprehensive Review

Drug Patent Watch

A recent paper in Expert Opinion on Biological Therapy studies failed fillings for biosimilar drugs. Over the past three decades, biotherapeutics have revolutionized healthcare by providing effective treatments for complex diseases… The post Unsuccessful Regulatory Filings for Biosimilar Approval: A Comprehensive Review appeared first on DrugPatentWatch - Make Better Decisions.

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Opinion: The best way for the NIH to reduce drug prices is to address drug spending

STAT

As STAT reported recently, the Senate Committee on Health, Education, Labor, and Pensions (HELP) has indicated that it will not consider the nomination of Monica Bertagnolli as director of the National Institutes of Health unless she pledges to take specific steps to reduce drug prices. However, the HELP Committee may want to focus on reducing drug spending , the product of price and units prescribed, rather than simply pricing.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Successful Drug Launches in a Digital-Forward Market: Q&A with Bridget Seay, Executive Director of Customer Experience & Commercial Consulting, epocrates

PharmExec

Bridget Seay of epocrates delves into drug launches in a digital-forward market, exploring how pharmaceutical companies can navigate complex patient journeys, strike a balance between traditional and digital marketing tactics, and ethically engage with healthcare professionals and empowered patients amidst ever-changing regulations.

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STAT+: FDA warns AstraZeneca over misleading promotional materials for a COPD drug

STAT

The Food and Drug Administration scolded AstraZeneca for making misleading claims about the effectiveness of a key medicine used treat chronic obstructive pulmonary disease. In an Aug. 4 warning letter , the agency admonished the company for a promotional sales aid that suggested the treatment, called Breztri, had a positive impact on death rates and reduced the risk of death in COPD patients.

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3 PioneerRx Features You Should Be Using

PioneerRx

The beauty of the independent pharmacy industry is how you can put your own unique spin on patient care. You’re helping patients your way, and your community is.

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America’s ERs struggle with timely care for stroke patients

STAT

In the world of stroke care, time is everything. At stroke onset, a clot or ruptured blood vessel interrupts blood flow to the brain. Within minutes, brain cells starved of oxygen and nutrients begin to die. Every additional second that passes without blood flow increases the chance that the brain suffers irreparable damage, leading to permanent disability.

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Gilead allies with targeted drug startup Tentarix in latest research bet

BioPharma Dive

San Diego-based Tentarix will receive $66 million in cash and equity from Gilead, which holds an option to acquire up to three of the company’s subsidiaries.

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YouTube cracks down on misinformation on cancer treatment

STAT

You’re reading the web edition of STAT Health Tech, our guide to how tech is transforming the life sciences.  Sign up to get this newsletter  delivered in your inbox every Tuesday and Thursday.

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FDA lifts hold on Arcellx’s Gilead-partnered cancer cell therapy

BioPharma Dive

The agency had paused testing after a patient death, but is now permitting more types of bridging treatment to help keep participants’ disease at bay.

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CPHI to return to Milan in 2024

European Pharmaceutical Review

CPHI, the global pharmaceutical event that spans the entire supply chain from ingredients and finished dosages to machinery, bio, and packaging will return to Fiera Milano (Rho) in 2024. The exhibition, which will take place from 8-10 October 2024, is being hosted in Milan for the second time in three years in recognition of the massive pharmaceutical ingredients and manufacturing industry in the region.

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Government reiterates commitments to prevention in major conditions strategy

The Pharmacist

The government has committed to ‘proactive prevention’ and community care in an interim report on its major conditions strategy, published this week. The strategy aims to tackle the prevalence of six major conditions that together drive over 60% of mortality and morbidity in England: cancer, chronic respiratory disease, dementia, cardiovascular disease and diabetes, musculoskeletal disorders […] The post Government reiterates commitments to prevention in major conditions strategy appeared

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Surprising Data on Employer-PBM Rebate Pass-Through Arrangements in 2023

Drug Channels

Hi, Barbie! The likelihood of major national legislation over the pharmacy benefit management (PBM) industry has never been greater. A serious effort exists to require greater transparency into PBMs’ activities and mandate full pass-through of rebates to plan sponsors. Today, I review some surprising new data on a crucial aspect of the drug channel: how employer-sponsored health plans access the billions of dollars in manufacturer rebates that are negotiated by their PBMs.

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Evgen releases data from SFX-01 trial

Pharma Times

The study is specifically analysing the company’s new enteric coated tablet formation of the drug - News - PharmaTimes

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Researchers publish early results with new interleukin-targeting antibody

Pharmaceutical Technology

The biologic was able to halt disease progression in rheumatoid arthritis with the same effectiveness as gold-standard treatment Remicade.

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Report: Hospitals Mark Up Medication Prices by 500%

Pharmaceutical Commerce

Analysis requested by PhRMA indicates that these facilities charge anywhere from two to seven times what they originally paid.

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Delayed payments to pharma MSMEs: A major challenge

Express Pharma

Small and Medium Enterprises (SMEs) form the backbone of India’s economy, contributing significantly to employment generation and economic growth. However, one of the major challenges faced by MSMEs in India is delayed payments. This issue has far-reaching consequences, affecting the financial stability and sustainability of these businesses. Reasons for delayed payments to pharma MSMEs Inefficient cash flow management by large companies, including delayed receivables processing and elonga

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Calliditas reveals results from vital NefIgArd study

Pharma Times

The study concerns the use of Nefecon among adult patients with primary IgA nephropathy - News - PharmaTimes

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Fluree and Vitality Technet partner to shorten timelines in drug discovery

Outsourcing Pharma

A partnership between technology company Fluree and Vitality TechNet is a âgroundbreaking effortâ to shorten timelines within the drug discovery process.

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Preparing for the tsunami of healthcare data approaching

pharmaphorum

Preparing for the tsunami of healthcare data approaching Mike.

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Sosei and Cancer Research UK announce first patient dosed with oral immunotherapy drug

Outsourcing Pharma

The first patient has been dosed with an orally available small molecule cancer immunotherapy drug, Sosei Group Corporation and Cancer Research UK have announced.

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Agnelli family invests €2.6bn in Philips despite recall woes

pharmaphorum

Agnelli family invests €2.6bn in Philips despite recall woes Phil.

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Calliditas Therapeutics advances kidney disease drug, meeting primary endpoint in study

Outsourcing Pharma

Calliditas Therapeutics ABâs phase 3 study looking at a cure for a kidney disease called IgA nephropathy (IgAN) has met its primary endpoint and the full data has been published in The Lancet.

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ADHD medication scarcity adds to questions on US supply chain

pharmaphorum

ADHD medication scarcity adds to questions on US supply chain Mike.

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Cancer-infecting virus 'warms up' cold tumors and improves immunotherapy

World Pharma News

Equipping cancer-infecting, or oncolytic, viruses with tumor-inhibiting genetic cargo stimulates the immune system and helps immunotherapy to shrink or completely clear aggressive tumors in mice, according to a new study in the Journal of Experimental Medicine led by University of Pittsburgh and UPMC researchers. The results pave the way for clinical trials combining oncolytic viruses with immunotherapy.

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Harmony buys cannabidiol firm Zynerba in $200m deal

pharmaphorum

Harmony buys cannabidiol firm Zynerba in $200m deal Phil.

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Capsule Application Lab services

PharmaTech

Introducing Lonza Capsules & Health Ingredients' groundbreaking enteric manufacturing technology - the Capsugel® Enprotect® capsule. This unique bi-layer capsule with the Coni-Snap® secure closure design ensures leak-free containment and maximum delivery of APIs. By utilizing HPMC and HPMC-AS polymers, it protects acid-sensitive APIs and enables rapid dissolution release at pH 6.8 without the need for additional excipients.

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Four digital weight-loss programmes get NICE support

pharmaphorum

Four digital weight-loss programmes get NICE support Phil.

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