Mon.Mar 11, 2024

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STAT+: UnitedHealth is on a buying spree of outpatient surgery centers

STAT

UnitedHealth Group quietly acquired dozens of outpatient facilities in 2023, with a particular focus on surgery centers, according to a STAT review of company financial filings. Those acquisitions — nearly all of which the company never announced — build on the network of some 90,000 physicians UnitedHealth Group has amassed in recent years.

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SAEM Clinical Images Series: Not Your Usual Irritated Eye

ALiEM - Pharm Pearls

In July 2022, a 32-year-old male with a past medical history of HIV (on antiretroviral therapy, CD4 390, viral load undetectable) presented to the emergency department with constitutional symptoms and a rash for 4-5 days. His symptoms included malaise, body aches, subjective fevers, a sore throat, tender, swollen neck glands, body rash, and irritation of his left eye.

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Opinion: Disabled scientists are often left out of academia. The NIH can help change that

STAT

Despite being the largest minority in the nation , disabled people like us have been structurally and institutionally obstructed from entering research-dominated fields. When they do manage to break through, they are seldom given the support and accommodations needed to sustain employment and thrive in their professional lives. As we have experienced, including people with disabilities in academic leadership and decision-making positions can lead to innovation, creative problem-solving, and insi

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Why pharma should prioritize the patient journey: A survivor’s story

PharmaVoice

One rare disease survivor’s diagnosis experience highlights the need for pharma companies to better understand the patient journey.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Amid the battle over abortion rights, a failure to agree on how to define abortion

STAT

Every year, Lisa Campo-Engelstein tells her medical ethics class the story of Isabel: A fictional character who arrives at a health clinic seeking an abortion. Doctors determine that Isabel is 37 weeks pregnant and, what’s more, she’s suffering from high blood pressure that endangers the life of the fetus. Thirty-seven weeks is just three shy of an average full-length pregnancy, so instead of an abortion, the clinic’s doctors recommend that Isabel have an emergency C-section

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COVID vaccine giants Moderna and Pfizer employ divergent tactics for the next chapter

PharmaVoice

With COVID-19 vaccine sales dying down, Pfizer and Moderna turn to growth in different ways to cement their status as mRNA leaders.

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More Trending

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Biotech stock fundings headed for best quarter in 3 years, Jefferies says

BioPharma Dive

Publicly traded companies raised nearly $10 billion in follow-on stock offerings in January and February, a financing surge that’s driving a “sector recovery,” the investment bank said.

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Experts say leaked messages present false link between gender-affirming care and cancer

STAT

Hundreds of messages from an internal chat board for an international group of transgender health professionals were leaked in a think tank report last week and framed as revealing serious health risks associated with gender-affirming care, including cancer. But experts say this correlation is false and oversimplifies the complex role of hormones in the body.

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Pain is reduced by almost half with cannabis-based medicines – report finds

Outsourcing Pharma

On March 7, Celadon Pharmaceuticals plc, a leading UK-based pharmaceutical company specializing in cannabis-based medicines, unveiled promising findings from an early economic analysis of its chronic pain clinical trial, dubbed CANPAIN.

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STAT+: Acadia’s Nuplazid fails as treatment for schizophrenia in Phase 3 study

STAT

Acadia Pharmaceuticals said Monday that its approved medicine called Nuplazid failed to improve the social and emotional symptoms of schizophrenia in a late-stage clinical trial.  The negative outcome of the Phase 3 study represents a setback in the company’s efforts to expand the use of Nuplazid into the treatment of schizophrenia. The medicine is currently approved to treat hallucinations and delusions associated with Parkinson’s disease psychosis.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Neurvati touts fresh, ‘synergistic’ investment model in neuroscience R&D

PharmaVoice

The Blackstone Life Sciences-backed company plans to focus on later-stage assets to help derisk development.

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Preventing the weaponization of AI-designed proteins

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Today, we talk about a new online marketplace to trade animal parts for research, an initiative to ensure ethics in AI-driven protein synthesis, and more.

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Amylyx CEOs look for a path forward following major setback

BioPharma Dive

Justin Klee and Joshua Cohen spoke to BioPharma Dive about the next steps for their company, which is considering pulling its only product from market after the drug failed a confirmatory study in ALS.

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STAT+: Pharmalittle: We’re reading about Wegovy approved for heart risks, an ALS drug puzzle, and more

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and invigorating, because that oh-so familiar routine of online meetings, calls, and deadlines has predictably returned. But what can you do? The world, such as it is, continues to spin. So time to give it a nudge in a better direction with a cup of stimulation.

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What’s next for AAV gene therapies in 2024?

Pharmaceutical Technology

Upcoming regulatory events for pipeline AAV gene therapies, with a focus on neuromuscular and blood disorders, are setting high expectations for the space in 2024.

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Amylyx plummets as confirmatory trial of ALS drug fails

pharmaphorum

Shares in Amylyx have cratered after the company reported a confirmatory trial of its amyotrophic lateral sclerosis (ALS) therapy Relyvrio missed all its objectives, putting its accelerated approval in jeopardy.

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Pharma Industry Townhall to be held in Mumbai

Express Pharma

The upcoming Pharma Industry Townhall by PharmaState Academy offers an array of insightful talks, panel discussions, and presentations. The details are as follows: Event Date: March 16, 2024 Location: Radisson Blu Marol Andheri Time: 09:00 AM – 05:00 PM The event aims to equip professionals with the latest knowledge and strategies crucial for navigating the industry’s changing dynamics.

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Boehringer, Sosei Heptares team up in schizophrenia drug deal

BioPharma Dive

Sosei Heptares could receive more than 700 million euros in a deal to develop medicines aimed at the protein GPR52, an emerging drug target in multiple neurological diseases.

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Enhancing clinical trials: The case for algorithmic prespecification in subgroup analysis

pharmaphorum

Enhancing clinical trial outcomes through algorithmic prespecification in subgroup analysis can provide valuable insights for the FDA and medical community. Learn more about this practice and its importance in clinical research.

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Roche, following setbacks, turns to its next Alzheimer’s drug

BioPharma Dive

Roche said its experimental Alzheimer’s disease drug trontinemab showed it might be able to clear brain plaques faster than other medicines.

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FDA clears Wegovy’s label to include heart health benefits

pharmaphorum

Novo Nordisk’s Wegovy has been given a first-in-class approval by the FDA to reduce the risk of serious cardiovascular conditions in people who are overweight or obese

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Advanced technologies in unlocking the future of drug manufacturing

BioPharma Dive

Innovative technologies, such as flow chemistry and biocatalysis, are achieving not only sustainability goals but also unprecedented levels of quality and efficiency.

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Control Print acquires majority stake in UK-based Codeology Group for £1 million

Express Pharma

Control Print, integrated coding and marking solutions provider, announced the acquisition of a majority stake in Codeology Group, a UK-based provider of print and apply systems. As a part of the deal, Control Print has acquired 50.49 per cent of the stake in the company for £ 1 million. Control Print plans to use Codeology’s Print and Apply systems in the Indian market in the next three months.

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Changing Faces: Pharma and biotech hires from February 2024

pharmaphorum

Stay updated with the latest pharma and biotech hires from February 2024 at companies like AbbVie, Astellas, EnteroBiotix, and Resalis Therapeutics in Changing Faces.

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‘Too many’ unaware of pharmacy blood pressure checks

The Pharmacist

Almost half of adults aged over 40 are unaware they can have a free blood pressure check at a community pharmacy, a survey commissioned by NHS England has suggested. The finding comes as part of a new national campaign launched today to find the ‘missing millions’ who have undiagnosed high blood pressure and to encourage […] The post ‘Too many’ unaware of pharmacy blood pressure checks appeared first on The Pharmacist.

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Developing new treatment regimens for HIV

European Pharmaceutical Review

Since the HIV epidemic began in the early 1980s, more than 85 million people have been diagnosed worldwide and about 40 million have died as a result of complications from the virus. 1 Now, four decades later, 39 million people around the world are living with HIV, primarily due to advances in treatment. 1 With continued innovation on the horizon in terms of prevention and treatment methods, what was once a wishful hope of ending the epidemic has become a conceivable goal.

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Warning signs for CAR-T after secondary cancer cases

pharmaphorum

Learn about the warning signs for potential secondary cancer cases related to CAR-T therapies. Understand the risks associated with cytokine release syndrome and other side effects of CAR-T treatment.

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Aspire Pharma acquires Cenoté Pharma

Pharmafile

Aspire Pharma has announced that it has successfully acquired Cenoté Pharma as part of its plan to supplement its growth using various acquisitions and strategic partnerships. This acquisition marks the fourth that Aspire Pharma has undertaken since it was acquired by an affiliate of HIG Capital in 2021. It is intended to strengthen the company’s […] The post Aspire Pharma acquires Cenoté Pharma appeared first on Pharmafile.

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This week in clinical trials: 12th to 16th February 2024

pharmaphorum

Stay updated on the latest developments in clinical trials with highlights from Medigene, Artax, and KalVista from 12th to 16th February 2024.

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Venus Remedies gets UNICEF GMP approval

Express Pharma

Venus Remedies has recently secured Good Manufacturing Practices (GMP) approval from the United Nations International Children’s Emergency Fund (UNICEF). Venus Remedies’ manufacturing unit, located in Baddi, Himachal Pradesh, India, has been recommended for supplying cephalosporin dry powder, a class of β-lactam antibiotic for treating bacterial infections, to UNICEF. hains.

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Boehringer licenses Sosei schizophrenia drugs in €755m deal

pharmaphorum

Boehringer Ingelheim has taken an option on a family of GPR52 agonist compounds with potential in schizophrenia from Sosei Heptares, in a €755m deal

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Medable's Colin Weller addresses challenges and future of clinical trials

Outsourcing Pharma

A conversation between Colin Weller, VP and GM of the evidence platform at Medable and Liza Laws, senior editor, at Outsourcing Pharma, was held at this yearâs SCOPE 2024 in Orlando.

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Preventing fungal contamination in pharmaceuticals

European Pharmaceutical Review

In a review on fungal-contaminated compounded pharmaceuticals and medical devices, researchers have described how the contamination of these products can be due to breaches in sterile compounding procedures. The authors explained: “inadequate sterile compounding techniques or storage conditions, or exceeding the limit of a fungal count, can result in fungal contamination.

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Can using SDoH data help identify patient populations who could benefit from weight loss drugs?

BioPharma Dive

SDoH data can help companies understand the footprint of weight loss medications in the market and their impact across populations.

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AAD: J&J’s oral IL-23 drug shows durability in psoriasis

pharmaphorum

J&J says oral IL-23 inhibitor JNJ-2113 shows a durable effect in psoriasis, making it a potential companion to its injectable Tremfya.

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