November, 2021

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University of Glasgow reveals drug design for new Alzheimer’s treatments

Pharma Times

A team of scientists and pharmaceutical collaborators have discovered a ‘bench to bedside’ drug design, which will hopefully improve the future treatment of Alzheimer’s disease.

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FDA clears GE Healthcare AI algorithm for patient intubation

pharmaphorum

An artificial intelligence algorithm developed by GE Healthcare that helps with the placement of endotracheal tubes (ETTs) has been approved by the FDA. The new tool – part of GE’s Critical Care Suite 2.0 – helps bedside staff and radiologists assess patients before intubation – for example prior to ventilation in patients with critical COVID-19 – and make sure their ETTs are positioned correctly.

Hospitals 145
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Trending Sources

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A Cure for Type 1 Diabetes? For One Man, It Seems to Have Worked.

NY Times

A new treatment using stem cells that produce insulin has surprised experts and given them hope for the 1.5 million Americans living with the disease.

Diabetes 145
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Gene-edited cell replacement therapy for diabetes set to enter the clinic

Outsourcing Pharma

CRISPR Therapeutics and ViaCyte, Inc. have received the green light from Health Canada for their Clinical Trial Application for VCTX210: an allogeneic, gene-edited, immune-evasive, stem cell-derived therapy for the treatment of type 1 diabetes (T1D).

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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New patent expiration for Glaxo Grp drug FLOVENT HFA

Drug Patent Watch

Annual Drug Patent Expirations for FLOVENT+HFA Flovent Hfa is a drug marketed by Glaxo Grp Ltd and is included in one NDA. It is available from four suppliers. There are…. The post New patent expiration for Glaxo Grp drug FLOVENT HFA appeared first on DrugPatentWatch - Make Better Decisions.

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Consolidation and Preferred Pharmacy Networks in 2022’s Medicare Part D Plans: Cigna, CVS Health, Humana, UnitedHealthcare, WellCare, and More

Drug Channels

Open enrollment is under way for the 2022 Medicare Part D plans. Our exclusive analysis of Center for Medicare & Medicaid Services’ (CMS) data reveals that preferred cost sharing pharmacy networks will maintain their dominance as an established component of Part D benefit design. For 2022: 98% of stand-alone Medicare Part D prescription drug plans (PDP) will have a preferred network. 66% of Medicare Advantage prescription drug (MA-PD) plans will have a preferred network.

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Trial of Jazz’ cannabis drug in glioblastoma will start next year

pharmaphorum

An investigator-led trial of Jazz Pharma’s cannabis extract-based drug Sativex in glioblastoma – an aggressive form of brain cancer – will get underway in the UK next year. The three-year phase 2 trial will be carried out by researchers at Leeds University led by professor of clinical oncology and neuro-oncology Susan Short, and see if adding Sativex (nabiximols) to standard chemotherapy for recurrent glioblastoma can extend survival.

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Will the Vaccines Stop Omicron? Scientists Are Racing to Find Out.

NY Times

A “Frankenstein mix” of mutations raises concerns, but the variant may remain vulnerable to current vaccines. If not, revisions will be necessary.

Vaccines 110
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Mix-and-match COVID-19 vaccines: New trial to add to growing body of research

Outsourcing Pharma

A new clinical trial of heterologous â or âmix-and-matchâ â combinations of COVID-19 vaccines is set to start in Pakistan: seeking to add to research on the effectiveness of such combinations.

Vaccines 111
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New patent for Alkermes Inc drug ARISTADA INITIO KIT

Drug Patent Watch

Annual Drug Patent Expirations for ARISTADA+INITIO+KIT Aristada Initio Kit is a drug marketed by Alkermes Inc and is included in one NDA. It is available from one supplier. There are…. The post New patent for Alkermes Inc drug ARISTADA INITIO KIT appeared first on DrugPatentWatch - Make Better Decisions.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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CVS, Walgreens, Walmart, and Supermarkets Keep Position in 2022 Part D Preferred Networks—With a Little Help from 340B

Drug Channels

In Consolidation and Preferred Pharmacy Networks in 2022’s Medicare Part D Plans , I highlighted how those networks have hijacked the world of stand-alone Medicare Part D prescription drug plans (PDP) and become a major presence in Medicare Advantage prescription drug (MA-PD) plans. Today, I examine the largest retail chains’ participation in the 21 major 2022 Part D preferred networks that the eight largest plan sponsors will offer.

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University of Oxford begins human trials of Ebola vaccine

Pharma Times

ChAdOxl biEBOV is being tested for safety and immunogenicity, and may protect against multiple species of the virus

Vaccines 163
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AI tool may help doctors select best drugs for COVID patients

pharmaphorum

Researchers in the US have developed an artificial intelligence-based tool that is able to predict COVID-19 symptoms and suggest which FDA-approved drugs might be used to treat patients. The MOATAI-VIR algorithm, developed by scientists at Emory University and Georgia Tech, was put through its paces in a study that showed it was able to predict 24 out of 26 clinical manifestations of COVID-19, including acute respiratory distress, blood clotting issues, cytokine storms, brain fog, and loss of sm

Diabetes 134
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Pfizer Will Allow Its Covid Pill to Be Made and Sold Cheaply in Poor Countries

NY Times

The company announced a deal that could help significantly expand access to the Covid-19 treatment, but the agreement excludes a number of countries hit hard by the pandemic.

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Gain Therapeutics presents hopeful data for Parkinson’s, Gaucher treatment

Outsourcing Pharma

The biotech firm has presented data from a study that could offer hope to patients with Parkinsonâs, Gaucher, Alzheimerâs and other neurodegenerative conditions.

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New patent expiration for Novartis drug AMTURNIDE

Drug Patent Watch

Annual Drug Patent Expirations for AMTURNIDE Amturnide is a drug marketed by Novartis and is included in one NDA. There are two patents protecting this drug. This drug has one…. The post New patent expiration for Novartis drug AMTURNIDE appeared first on DrugPatentWatch - Make Better Decisions.

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Pathway or Perish: The Two-Pronged Hurdle to Ensuring Access in Oncology

Drug Channels

Today’s guest post comes from Carolyn Zele, Senior Manager of Solution Enablement at MMIT. Carolyn describes how oncology pathways were developed to help standardize treatment and ensure quality care. She argues, however, that these pathways often shut manufacturers out of the market. Click here to learn more about MMIT's Pulse Analytics solution , which provides insight into payer- and pathway-driven barriers to access.

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EC grant Trodelvy marketing authorisation for treatment of breast cancer

Pharma Times

With the latest approval from the EC, patients in Europe suffering from metastatic triple-negative breast cancer can now receive Gilead Science’s Trodlevy as part of their treatment.

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Digital therapeutic cuts opioid use disorder care costs, says study

pharmaphorum

A real-world study of digital therapeutic (DTx) for opioid use disorder has found that patient show used it had 46% fewer hospital stays than a control group, saving more than $2,700 over a nine-month period. The study of Pear Therapeutics’ reSET-O found that the total cost of hospital and clinician costs were $11,141 among 64 patients who were prescribed the DTx but didn’t use it, but fell to $8,733 among active users of the 12-week course.

Hospitals 130
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U.S. to Buy Enough of Pfizer’s Covid Antiviral Pills for 10 Million People

NY Times

The antiviral drugs have helped inspire hope among senior administration officials that the United States will be able to curb the devastating toll from the Delta variant.

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Genetic testing offers powerful weapon for detecting breast cancer: Sema4

Outsourcing Pharma

A leader from the health tech solutions company explains how progress in genetic testing has helped advance the detection and prevention of breast cancer.

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New patent for Allergan Holdings drug VIBERZI

Drug Patent Watch

Annual Drug Patent Expirations for VIBERZI Viberzi is a drug marketed by Allergan Holdings and is included in one NDA. It is available from one supplier. There are sixteen patents…. The post New patent for Allergan Holdings drug VIBERZI appeared first on DrugPatentWatch - Make Better Decisions.

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Ep.015 – RJ Lewis and David Hunt, CEO of The Considered: Breaking the Rules in Pharma Advertising – November 3, 2021

Pharma Marketing Network

November 3, 2021 – Tune in with the Pharma Marketing Network for an exciting conversation with R.J. Lewis and David Hunt, CEO of The Considered, as he shares how his new independent agency, The Considered, about how they are breaking the rules in pharma advertising. David discusses and answers questions around: How The Considered is different. What launched the conception of the agency?

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Late cancer diagnoses rise as NHS struggles with COVID-19

Pharma Times

Analyses provided by UK cancer charity Macmillan has provided insights into the repercussions experienced by patients waiting to receive treatment during the COVID-19 pandemic.

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Boost for Amazon’s telehealth business, as Hilton signs up

pharmaphorum

Amazon’s push into the provision of remote healthcare services has been rewarded with a top-tier corporate client – the Hilton hotel chain. The deal – first reported by Reuters – involves the Amazon Care platform, which includes remote, online consultations with clinicians, as well as home visits in some areas. It provides primary and preventive care, ongoing support for chronic conditions, and referrals to secondary and tertiary care.

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F.D.A. Authorizes Coronavirus Booster Shots for All Adults

NY Times

If the C.D.C. agrees, adults who received a second shot of the Pfizer or Moderna vaccine at least six months ago could be eligible by this weekend.

Vaccines 105
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FDA approves BioMarin drug to treat dwarfism in children

Outsourcing Pharma

The US agency has granted approval to Voxzogo, an injectable drug designed to aid growth in children with achondroplasia, the most common form of dwarfism.

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CVS Pharmacy Downsizes: 10 Industry Trends Driving the Retail Shakeout

Drug Channels

ICYMI, CVS Health recently announced that it will close about 900 of its retail pharmacies. This downsizing complements the company’s shift toward its healthcare delivery future. This long-overdue move highlights the retail industry’s fundamental economic headwinds. The pharmacy shakeout is accelerating, as smaller competitors exit and larger companies reduce store count.

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New patent for Chiasma drug MYCAPSSA

Drug Patent Watch

Annual Drug Patent Expirations for MYCAPSSA Mycapssa is a drug marketed by Chiasma and is included in one NDA. It is available from one supplier. There are seven patents protecting…. The post New patent for Chiasma drug MYCAPSSA appeared first on DrugPatentWatch - Make Better Decisions.

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Pfizer’s COVID-19 pill cuts hospitalisation/death risk by 89%

Pharma Times

The trial evaluated the investigational medicine in non-hospitalised adult patients with COVID-19 who are at high-risk of progressing to severe illness

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AZ, Moderna say mRNA drug is promising in heart failure

pharmaphorum

Moderna is already riding high on the strength of its mRNA-based COVID-19 vaccine, but the broader potential of its technology has been shown in a new AstraZeneca-partnered candidate for heart failure. At the American Heart Association (AHA) congress, the two partners presented results from the phase 2a EPICCURE trial that showed that injecting their AZD8601 candidate directly into the heart muscle of patients undergoing coronary artery bypass graft (CABG) surgery seemed to improve heart functio

Vaccines 124
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CVS, Walgreens and Walmart Fueled Opioid Crisis, Jury Finds

NY Times

This is the first jury verdict in an opioid case. The decision embraced a key legal argument that judges in other opioid cases had recently rejected.

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Variable-dose pen injector platform designed for simple use

Outsourcing Pharma

Stevanato Group is showcasing its SG Alina disposable, variable-dose pen injector platform, available with customizable features, at CPhI Worldwide 2021.

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Why PBMs and Payers Are Embracing Insulin Biosimilars with Higher Prices—And What That Means for Humira

Drug Channels

The Food & Drug Administration (FDA) recently approved the first interchangeable biosimilar insulin product: the insulin glargine-yfgn injection from Viatris. Read the FDA’s press release. Alas, I’m sad to report that the warped incentives baked into the U.S. drug channel will limit the impact of this impressive breakthrough. Viatris is being forced to launch both a high-priced and a low-priced version of the biosimilar.

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New patent expiration for Allergan drug SAVELLA

Drug Patent Watch

Annual Drug Patent Expirations for SAVELLA Savella is a drug marketed by Allergan and is included in one NDA. It is available from three suppliers. There are four patents protecting…. The post New patent expiration for Allergan drug SAVELLA appeared first on DrugPatentWatch - Make Better Decisions.

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