STAT

JANUARY 12, 2023

The percentage of U.S. kindergartners who’ve received standard childhood vaccines took a small but notable dip into the 2021-2022 school year, health officials said Thursday, amid disruptions related to Covid-19 and fears that anti-vaccine sentiment stirred up by the pandemic could be spreading to other shots. Vaccinations among children remain high, but the trend — with coverage dropping from about 95% in the 2019-2020 school year to 94% in 2020-2021 to 93% in 2021-2022, according

Vaccines 362

Vaccines 362

PharmaVoice

JANUARY 11, 2023

The chief strategy officer of Form Bio is harnessing the new company’s computing power and bioinformatics to spur a genomic revolution.

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Pharmaceutical Technology

JANUARY 13, 2023

Health Canada has granted approval to Enhertu (trastuzumab deruxtecan) to treat unresectable or metastatic HER2-low (IHC 1+ or IHC 2+/ISH-) breast cancer. Enhertu has been approved to treat HER2-low breast cancer adult patients who have previously received at least one line of chemotherapy in the metastatic setting or who have seen disease recurrence during or within six months after the adjuvant chemotherapy.

Adverse Reactions 128

Adverse Reactions Chemotherapy 128

pharmaphorum

JANUARY 12, 2023

Bayer has signed an agreement with Google aimed at using high-level processing power to handle quantum chemistry calculations used to predict the chemical and physical properties of drug molecules at the atomic scale. The deal with the tech giant’s Google Cloud unit revolves around its tensor processing units (TPUs), artificial intelligence-powered accelerators designed to run machine learning models and computationally-intensive workloads that can be customised to specific applications.

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Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

STAT

JANUARY 12, 2023

Ready or not, health care is undergoing a massive transformation driven by artificial intelligence. But medical schools have barely started to teach about AI and machine learning — creating knowledge gaps that could compound the damage caused by flawed algorithms and biased decision-support systems. “We’re going to be at a point where we’re not going to be able to catch up and be able to call out the technology defects or flaws,” said Erkin Ötleş, a

Medical Schools 356

Medical Schools Compounding 356

PharmaVoice

JANUARY 12, 2023

Merck, Bristol Myers Squibb and others are taking small R&D steps in space that could lead to giant leaps for patients.

Drug Development 264

Drug Development 264

pharmaphorum

JANUARY 11, 2023

Over the past few decades, data generation has veritably exploded. However, the ‘Big Data paradigm’ is not so much concerned with the volume of that data, but how businesses and, indeed, industries can derive meaningful insights from what has become a glut of information. With the currently popular approach to artificial intelligence (AI) focussing on the Big Data paradigm, also, pharmaphorum spoke with Adityo Prakash, CEO of Verseon, about the whys and wherefores, delving deeper into the proces

Compounding 117

Compounding Drug Development 117

STAT

JANUARY 10, 2023

Mistakes happen — in life, in the lab, and, inevitably, in research papers, too. Journals use corrections and retractions to resolve those mistakes. But one particularly high-profile case is now drawing fresh attention to the problems with journals’ process for addressing concerns about research integrity. Late last year, Stanford University announced that it was opening an investigation into its president, neuroscientist Marc Tessier-Lavigne, over allegations of research misconduc

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PharmaVoice

JANUARY 9, 2023

How the IRLAB Therapeutics CEO is guiding the company in its development of potentially groundbreaking Parkinson’s disease treatments.

Drug Development 246

Drug Development 246

European Pharmaceutical Review

JANUARY 11, 2023

Machine learning models used to guide the design of long-acting injectable drug formulations have been successfully tested by scientists at the University of Toronto. The research results signal the potential for machine to reduce reliance on trial-and-error testing, which slows the development of long-acting injectables (LAIs). The study was published Nature Communications and is one of the first to apply machine learning techniques to the design of polymeric long-acting injectable drug formula

Communication 114

Communication 114

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pharmaphorum

JANUARY 9, 2023

Novartis’ programme providing free access to its spinal muscular atrophy (SMA) gene therapy Zolgensma is being scaled back to a dozen countries worldwide, according to the company. First introduced in 2020, the global Managed Access Programme (gMAP) has provided Zolgensma (onasemnogene abeparvovec) free of charge to nearly 300 children with the genetic disorder across 36 countries where the therapy has not yet received approval or in which no formal access pathway exists.

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STAT

JANUARY 11, 2023

The air in Mexico City was once so toxic that people watched as dead birds fell out of the sky. In 1992, the United Nations declared the city the most polluted in the world, with its unregulated diesel engines, factory production, fossil-fuel powered energy plants, and widespread use of internal-combustion engines, all trapped in a high-altitude, mountain-lined valley.

Medical Schools 323

Medical Schools 323

PharmaVoice

JANUARY 13, 2023

Execs at JPM sound off on moves companies can make to survive the challenging market conditions.

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245

PharmExec

JANUARY 11, 2023

As new forms of cell and gene therapies continue to be developed, life sciences companies and payers need to find alternative ways to pay for these expensive treatments. Value-based contracts, though slow to gain traction so far, may provide the solution these groups are looking for.

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pharmaphorum

JANUARY 9, 2023

We’re preparing to start JP Morgan week with a busy day Monday, with day 1 of the Informa Biotech Showcase, including a dedicated mini-event on Cell and Gene Therapy in the morning. Then in the evening, we’ll be at STAT@JPM for presentations by event sponsor GSK as well as the guest of honour: FDA Commissioner Robert Califf. Check below for updates throughout the day.

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STAT

JANUARY 13, 2023

Oscar Health has excelled at one thing in particular since its inception a decade ago: burning cash. The health insurance company did not plan to be profitable immediately. It was staking its future on the new Affordable Care Act marketplaces and had to grow quickly to compete with larger insurance carriers. Oscar organized its health insurance product through an app, promoted virtual care, advertised on New York subways, and then low-balled prices in certain markets to attract young, healthy pe

Health Insurance Companies 316

Health Insurance Companies 316

PharmaVoice

JANUARY 10, 2023

A breakdown of the most buzzworthy executive changes so far in the new year and how they’re causing ripples in the life sciences industry.

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147

Pharma Times

JANUARY 13, 2023

Company becomes the latest member of the ABPI and galvanises the company’s UK connections

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pharmaphorum

JANUARY 8, 2023

Before the main event at JP Morgan 2023 even kicks off, we’re checking out the Sachs Associates Neuroscience Innovation Forum on Sunday. Speakers from Lilly, Boehringer Ingelheim, Takeda, and many more pharma firms big and small will present on key trends and developments in one of the most exciting areas of pharmaceutical and digital innovation. We’ll also wander over to the UC Davis Health Future & Health CEO Summit a little later this afternoon.

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STAT

JANUARY 7, 2023

Joan Cohrs missed her chance to grab a prescription at her usual drugstore by about 30 seconds. Cohrs walked up to the counter of an Indianapolis CVS pharmacy shortly after a metal curtain descended, closing it for lunch. She didn’t mind. The 60-year-old said she feels compassion for people in health care.

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European Pharmaceutical Review

JANUARY 11, 2023

The largest microbiome study conducted at the highest resolution concluded the gut microbiome is involved in multiple pathways in the pathogenesis of Parkinson’s disease (PD). The findings, published in Nature Communications , show a wide imbalance in microbiome composition in people with Parkinson’s. Investigators at the University of Alabama at Birmingham, US employed metagenomics, the study of genetic material recovered directly from the stool microbiome of individuals with PD and neurologica

Communication 100

Communication 100

PharmaTech

JANUARY 11, 2023

We have proposed a comprehensive capping index parameter which is a ratio of compact anisotropic index to material anisotropic index. This study will help to design or select right tooling for successful tablet manufacturing.

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pharmaphorum

JANUARY 10, 2023

mRNA specialist BioNTech has driven its partnership with UK artificial intelligence InstaDeep into top gear, agreeing to buy the company outright in a cash and equity deal that values it at up to £562 million ($683 million). The deal , billed as BioNTech’s largest to date and unveiled at the JP Morgan healthcare conference today, includes $362 million upfront with another £200 million on offer if performance targets are met.

Immunity 113

Immunity Immunization Vaccines 113

STAT

JANUARY 10, 2023

The Food and Drug Administration’s approach to evaluating some new medical devices might actually increase the risk that those devices will later be recalled over safety concerns. For some medical devices, the FDA requires data from studies in people to show that the device, including things like implantable heart defibrillators or stents, is safe and effective.

Medical Schools 312

Medical Schools 312

Pharmaceutical Technology

JANUARY 9, 2023

Eisai and Biogen have received approval for their antibody Leqembi (lecanemab-irmb) , 100mg/mL injection for intravenous use, from the US Food and Drug Administration (FDA) under the Accelerated Approval Pathway to treat Alzheimer’s disease (AD). Leqembi is indicated to treat mild cognitive impairment or mild dementia stage of the disease in patients whose treatment started in clinical trials.

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PharmExec

JANUARY 9, 2023

"The customer is always right" — a commitment to omnichannel marketing is a commitment to serving the customer. David Laros of Beghou Consulting offers up this tersely written playbook on the topic.

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pharmaphorum

JANUARY 13, 2023

The ‘big three’ insulin producers Novo Nordisk, Eli Lilly, and Sanofi are being sued by the state of California for allegedly working together to set artificially inflated prices for their products. The lawsuit also takes aim at the three largest pharmacy benefit managers (PBMs) in the US – CVS Caremark, Express Scripts, and OptumRx – which are accused of adopting a system of rebates that incentivise manufacturers to raise list prices for insulin and promote higher-priced products.

Diabetes 103

Diabetes Drug Pricing Biosimilars 103

STAT

JANUARY 12, 2023

WASHINGTON — Medicare officials have taken a step toward making a cutting-edge cancer treatment called CAR T-cell therapy available in doctor offices, in anticipation of the procedure being used for increasingly common cancer types. CAR-T is a relatively new medical procedure that uses a person’s own cells to fight their cancer, and it offers hope of a cure for those who have run out of options.

Inpatient 299

Inpatient Hospitals 299

Pharma Pathway

JANUARY 7, 2023

Sun Pharma- Walk-In Drive for QC/ Production On 8th Jan’ 2023 & Send Resumes for Engineering/ QA/ Warehouse. Job Description. Walk-In Interview for Sun Pharma, Paonta Sahib On 8th Jan’ 2023. We are Hiring @ Sun Pharma, Paonta Sahib. Department: QC/ Production. Education: ITI/ Diploma/ 10+2/ M.Sc (Chem) B.Pharm/ M.Pharm. Experience: 02 to 10 years.

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Pharmaceutical Technology

JANUARY 10, 2023

AstraZeneca has signed a definitive agreement to buy US-based biopharmaceutical company CinCor Pharma in a deal valued at about $1.8bn. Under the deal, the company will initiate a tender offer to purchase all the outstanding shares of CinCor Pharma for $26 per share in cash. The transaction also includes a non-tradable contingent value right of $10 per share in cash which will be paid after a specified regulatory submission of CinCor’s lead drug candidate, baxdrostat (CIN-107).

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pharmaphorum

JANUARY 10, 2023

Data is transforming life sciences, but many organisations are not using its full potential. Life sciences and the pharmaceutical industry are awash with data. It flows from every direction in torrents to create huge opportunities to address the world’s mounting health issues. Approximately 30% of global data volume is generated by the healthcare industry and it will continue to expand with a compound annual growth rate predicted to reach 36% by 2025, according to research by RBC Capital Markets

Compounding 98

Compounding Communication Pharmaceutical Companies Pharmaceutical Companies 98

STAT

JANUARY 12, 2023

It’s like clockwork now. Every few months, we’re warned that the Omicron variant of the SARS-CoV-2 virus has spawned yet another subvariant, this one even more transmissible than the ones it is fast overtaking. The new entity is given a name, an unwieldy string of letters and numbers separated by periods. There’s discussion — some of it breathless — on Twitter and in the media about the threat the new subvariant poses.

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The Guardian - Pharmaceutical Industry

JANUARY 10, 2023

Researchers find overall percentage increase from 0.06% in 2000 to 0.11% in 2019 although safety in children not fully established The proportion of children and young people prescribed antipsychotics in England has nearly doubled in just two decades, prompting concern among some experts. The powerful drugs are often used to treat major mental illnesses, such as schizophrenia, in adults.

Diabetes 97

Diabetes 97

Pharma Times

JANUARY 11, 2023

Candidate will go through the development programme, which includes safety and tolerability studies

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pharmaphorum

JANUARY 10, 2023

Tuesday brings the on-site part of Fierce’s JPM event as well as day 2 of the Informa Biotech Showcase. We’ll do our best to surf between the two, as well as providing remote updates where we can from the main event. Fierce’s event “The long haul: How pharma and healthcare can survive in 2023” will feature guests from Bayer, Takeda, Genentech, and more.

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