Sat.Jul 01, 2023 - Fri.Jul 07, 2023

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Most ambulances ‘run hot’ with lights and sirens blaring. But that’s starting to change

STAT

Jonathan Studnek knows some people imagine that driving an ambulance at high speed with lights flashing and sirens wailing — racing through messily parted traffic to the scene of a crisis — is the best part of being an emergency medic. For him, that couldn’t be further from the truth. “If you’ve been in the industry for any length, you know innately: When you’re in the front of an ambulance and the lights are on, that’s the most dangerous situatio

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Following FDA’s full approval of Leqembi, here’s what else is in the Alzheimer’s pipeline

PharmaVoice

Leqembi’s U.S. approval is a milestone in Alzheimer’s research and medicine — and there are a few other late-stage biologic drugs that could follow.

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DigitalHealth.London’s Accelerator programme selects Aide

Pharma Times

Project aims to boost the adoption of technology across London’s NHS and help patients manage conditions - News - PharmaTimes

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Pfizer backs CRISPR biotech Caribou in latest cell therapy investment

BioPharma Dive

Five years after helping launch Allogene Therapeutics, Pfizer is backing another developer of “off-the-shelf” cell therapies in a deal that gives the drugmaker the chance to acquire a multiple myeloma treatment.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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What the end of affirmative action means to a fourth-year medical student

STAT

When the U.S. Supreme Court released its landmark ruling overturning the use of race-conscious college admissions, LaShyra Nolen was on clinical rotation. For Nolen, a fourth-year medical student at Harvard Medical School, the news sent a chill down her spine even though she had been anticipating it. “It felt very lonely,” said Nolen, who is Black and the first in her family to get a bachelors of science degree and attend medical school.

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Pharma’s strike-from-all-sides attack on the IRA could be decided by the Supreme Court

PharmaVoice

New lawsuits challenging the Inflation Reduction Act’s price negotiation program hit the government with multiple Constitution-based challenges.

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More Trending

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With new data, J&J steps forward in growing race for oral autoimmune drugs

BioPharma Dive

Phase 2 results show a pill the company is developing is competitive with other oral medicines in testing against psoriasis, among them the TYK2 inhibitors that have drawn significant industry interest.

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STAT+: Novo Nordisk bought prescribers over 450,000 meals and snacks to promote drugs like Ozempic

STAT

WASHINGTON – Novo Nordisk spent $11 million on meals and travel for thousands of doctors last year, federal records show, as part of its push to promote Ozempic and other weight loss-inducing diabetes drugs. The pharmaceutical company bought more than 457,000 meals to educate doctors and other prescribers about its portfolio of drugs known as GLP-1 agonists, according to the newly released data from the Centers for Medicare and Medicaid Services.

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Women’s healthcare investments are hot. So where are the new menopause drugs?

PharmaVoice

NK3 receptor antagonists offer a new option, but experts say more are needed.

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Health Equity in Pharma: Communities Most Impacted by Racial Bias

PharmExec

Rose Blackburne, MD, MBA, vice president, global head, general medicine, PPD Clinical Research, Thermo Fisher Scientific, discusses health equity in pharma, specifically racial biases, and how the industry can address inequities in access and care going forward.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Episode 831: What is the role for ketamine in refractory status epilepticus?

Pharmacy Joe

In this episode, I’ll discuss the role for ketamine in status epilepticus. Episode 831: What is the role for ketamine in refractory status epilepticus? Subscribe on iTunes , Android , or Stitcher The initial therapy for status epilepticus is to use one of the following benzodiazepines: Lorazepam 0.1 mg/kg capped at 4 mg IV Midazolam 0.2 mg/kg capped at 10 mg IM Diazepam 0.15 mg/kg capped at 10 mg IV But what happens if the patient does not respond to this initial therapy?

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As psychedelics near approval, there’s no consensus on how they work

STAT

DENVER — The founder of Field Trip , a chain of shuttered ketamine clinics currently facing insolvency, put forward an unexpected theory of how psychedelics work to treat depression last month. “The truth is, almost all of the effect of psychedelic-assisted therapy could be placebo,” said Ronan Levy, speaking at a five-day conference on the emerging field of psychedelic medicine.

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Eli Lilly’s retatrutide sets new record for weight loss in obesity space

Pharmaceutical Technology

Pipeline developments within the obesity space have recently garnered interest following recent results published on Eli Lilly’s retatrutide.

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Women in Science: How Charco Neurotech's Lucy Jung is 'restoring joy' for Parkinson's patients

Outsourcing Pharma

Lucy Jung is the CEO and founder at Charco Neurotech, a medtech start-up which has developed the CEU1, a non-invasive wearable device for Parkinson's, that uses vibrotactile stimulation to reduce symptoms of slowness and stiffness resulting in improved movement. We spoke to her about her background, how she got involved in the Parkinson's space and her fascination for problem-solving.

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Toxic Leadership in Healthcare

The Honest Apothecary

Jeremy, an HR business partner to the nursing staff of a medium sized community hospital, arrived at his desk at 8:30am on Monday to a familiar sight. There, sitting on his desk, was yet another resignation letter from a nurse on the 7th floor. Tina’s floor. Over the past 6 months Jeremy had 5 such letters reach his desk. Each one a subtle reminder to him that his organization is dealing face-to-face with the problem with toxic leadership in healthcare. “I regret to inform you that m

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Why depression after traumatic brain injury is distinct — and less likely to respond to standard treatment

STAT

Traumatic brain injury multiplies the risk of major depression eightfold. While the emotional trauma of whatever caused such deep damage may be understandable, from a blast in a war zone to a blow on the playing field, there’s a physiological component, too, that neuroscientists have long suspected but have been unable to identify. “As clinicians, a lot of us had a gut feeling that [TBI-associated depression] is a different disease,” said Shan Siddiqi, a Harvard Medical Scho

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Embracing the Hybrid Era: Leveraging Answer Engines and Generative AI to Improve the Patient and HCP Experience

PharmExec

Through the power of large language models and generative AI, pharma and biotech companies are transforming medical information delivery by offering direct, trustworthy, and accurate answers to patients and healthcare providers, significantly reducing time and frustration.

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Rationing strategies proliferate with cancer drugs in short supply

Pharmaceutical Technology

While drug shortages have been a major cause for concern over the past few years, medications to treat cancer are in particularly short supply.

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New patent expiration for Bayer Hlthcare drug LEVITRA

Drug Patent Watch

Annual Drug Patent Expirations for LEVITRA Levitra is a drug marketed by Bayer Hlthcare and is included in one NDA. There are two patents protecting this drug and three Paragraph… The post New patent expiration for Bayer Hlthcare drug LEVITRA appeared first on DrugPatentWatch - Make Better Decisions.

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STAT+: FDA approves first Alzheimer’s therapy shown to clearly slow cognitive decline

STAT

The Food and Drug Administration on Thursday granted full approval to the first therapy for Alzheimer’s disease clearly shown to slow the cognitive decline associated with the disease — a milestone in treatment, even if the benefits are modest. The drug, called Leqembi , was developed by Eisai , the Japanese pharmaceutical company, and sold in partnership with Biogen.

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AI Frontiers: Navigating the Risks, Rewards, and Regulations

PharmExec

Senior editor Fran Pollaro chats with Sharlene Jenner, vice president of engagement strategy, Abelson Taylor about the transformative impact and ethical considerations of AI in the pharmaceutical industry, emphasizing its potential in data analysis and marketing, while also highlighting the pioneering work of AI companies in advancing drug discovery.

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HRT and the risk of dementia: Should users be worried?

The Pharmacist

With a recent study in the BMJ suggesting an increased risk of dementia in those using hormone replacement therapy (HRT), should women now peel off their patches? Rod Tucker investigates, in the first in a Review series of articles for the Pharmacist. The menopause represents a normal physiological change that occurs on average in women […] The post HRT and the risk of dementia: Should users be worried?

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Novavax COVID-19 vaccine produces immunity

Pharma Times

Second dose of treatment generates response among young people during Oxford University trial - News - PharmaTimes

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New Biden initiative targets controversial hospital ‘facility fees’ that often surprise patients

STAT

As part of the Biden administration’s broader efforts to lower health care costs, the White House announced new guidelines on Friday targeting a few of the most common sources of sticker shock. The new policy initiatives target some of the usual suspects: surprise billing , which was restricted in 2020 yet persists as health care providers exploit loopholes ; short-term insurance policies that often fail to cover essential treatment; and high-interest credit cards and payment plans especi

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Biotech’s Survival Story: Companies Bear Down for Lean Years

PharmExec

While large pharma investment in biotechs is down—as pharmas become more strategic in their selections—it is scarcely out, with the partnership dynamic between the two sides remaining strong.

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Probe into UKHSA finds weak financial controls and 'alarming' lack of pandemic planning

The Pharmacist

The UK Health Security Agency (UKHSA) was set up with financial controls ‘so poor’ that it cannot establish whether its transactions were in line with its purpose as laid out by parliament. This meant that the UKHSA’s £3.3bn worth of inventory transferred from NHS Test and Trace could not be verified by proper financial records. […] The post Probe into UKHSA finds weak financial controls and 'alarming' lack of pandemic planning appeared first on The Pharmacist.

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Complex road ahead, despite phase 3 progress, for Annovis’ buntanetap in Parkinson’s Disease

Outsourcing Pharma

Drugs like Annovis Bioâs buntanetap and prasinezumab have the potential to ârevolutionize the treatment of Parkinsonâs Diseaseâ says analytics company, GlobalData, an analytics company, but it is a complex road ahead.

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Opinion: We finally have new Alzheimer’s drugs. How do we decide who gets them?

STAT

The recent FDA approval of Leqembi , the latest anti-amyloid drug, is undoubtedly a breakthrough for the field, providing a new way to slow the advancement of mild cognitive impairment or early-stage Alzheimer’s disease. As a practicing geriatrician who has treated Alzheimer’s patients for more than 40 years and the co-founder and chief science officer at the Alzheimer’s Drug Discovery Foundation, I have never been more optimistic about our potential to transform how we trea

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Teva reveals critical Ajovy data

Pharma Times

Therapy has been developed to reduce the frequency, duration and severity of migraine attacks - News - PharmaTimes

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CCA chief: NHS and DHSC must decide what they want – and how they will pay for it

The Pharmacist

The community pharmacy sector can help design a solution to the needs of the health service if NHS England and the Department of Health and Social Care (DHSC) set out a clear vision for what they want, and how they are going to pay for it, the chief executive of the Company Chemists’ Association (CCA) […] The post CCA chief: NHS and DHSC must decide what they want – and how they will pay for it appeared first on The Pharmacist.

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ISO publishes standard on bacterial endotoxin testing

European Pharmaceutical Review

The International Organization for Standardization (ISO) has published its new standard Sterilization of health care products — Microbiological methods — Part 3 Bacterial endotoxin testing ( ISO 11737-3:2023). The document contains requirements and guidance for testing for bacterial endotoxins. This includes products that must be non-pyrogenic based on either intended use or non-pyrogenic label claim, or both.

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Opinion: Biden promised a ‘war on cancer’ — but declared war on the cure instead

STAT

When then-Vice President Biden launched the Cancer Moonshot in 2016, there was reason to be optimistic. Decades of rigorous science had transformed many cancers from a death sentence to a manageable chronic disease. New treatment advances — including gene and cell therapies and immunotherapies — were showing stunning results. With support from the biopharmaceutical industry and the help of smart government policies, ending cancer was, and is, an achievable goal.

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The Importance of a Good Onboarding Process

The Honest Apothecary

In the realm of talent acquisition, the pivotal role of the interviewing process in selecting the right candidates cannot be overstated. After all, it is during these crucial interactions that potential employees showcase their skills, experience, and cultural fit. However, as acclaimed author and business leader Stephen Covey once wisely remarked, “Hire for character, train for skill.” This quote encapsulates a fundamental truth.

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More detail on proposed pharmacist apprenticeships needed

The Pharmacist

Pharmacist degree apprenticeships are being considered as part of NHS England’s plan to increase the workforce. In the NHS Long Term Workforce Plan, published last week (30 June), NHS England (NHSE) said there was potential for pharmacy technicians to undertake expanded training via apprenticeships, and that consideration was being given to the potential of […] The post More detail on proposed pharmacist apprenticeships needed appeared first on The Pharmacist.

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Sustainable pharmaceuticals: what about pine-based painkillers?

European Pharmaceutical Review

Scientists have created paracetamol and ibuprofen, two of the world’s most common painkillers, out of turpentine (β-pinene), a compound found in pine trees. Turpentine is also a waste product from the paper industry. According to the research published in the journal ChemSusChem , the quantity of this waste generated worldwide is enough to supply the global demand for paracetamol and ibuprofen.