STAT

APRIL 14, 2023

Black people in counties with more Black primary care physicians live longer, according to a new national analysis that provides the strongest evidence yet that increasing the diversity of the medical workforce may be key to ending deeply entrenched racial health disparities. The study , published Friday in JAMA Network Open, is the first to link a higher prevalence of Black doctors to longer life expectancy and lower mortality in Black populations.

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ALiEM - Pharm Pearls

APRIL 12, 2023

Ever finally step away from a busy resuscitation and someone stops you for peripheral IV access? You set up everything, have the patient positioned, and then notice there is no sterile ultrasound gel. No gel? No problem. The trick is to eliminate anything of poor acoustic impedance between the ultrasound probe and the patient’s skin. Trick of the Trade 1.

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PharmaVoice

APRIL 12, 2023

Pharma’s missing the mark when it comes to recruiting Black patients, and Ricki Fairley, CEO of The Black Breast Cancer Alliance, reveals what’s needed.

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BioPharma Dive

APRIL 13, 2023

The Danish drugmaker nearly doubled the 2023 forecasts for Wegovy and Ozempic in the latest indicator of the sales potential of an emerging and competitive class of weight loss drugs.

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Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

STAT

APRIL 14, 2023

On most days around 2pm, home health aide Duane Crichlow can be found in an apartment in Sunset Park, Brooklyn, playing catch with his client — a man in his 30s with a developmental disability who is quick to give Crichlow hugs and kisses. If it’s nice outside, Crichlow will walk his client, who is nonverbal and in a wheelchair half the time, down three flights of stairs, hauling the wheelchair back and forth separately.

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ALiEM - Pharm Pearls

APRIL 14, 2023

Welcome to the AIR Procedures Module! After carefully reviewing all relevant posts in the past 12 months from the top 50 sites of the Social Media Index, the ALiEM AIR Team is proud to present the highest quality online content related to related to procedures in the Emergency Department. 6 blog posts met our standard of online excellence and were approved for residency training by the AIR Series Board.

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Labelling 246

BioPharma Dive

APRIL 12, 2023

For an upfront payment of $75 million, Novo gets an exclusive license to use Aspect Biosystems’ “bioprinting” technology to develop as many as four treatments for the diseases.

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Diabetes 122

STAT

APRIL 14, 2023

WASHINGTON — Even though the Biden administration is ending its highest-profile Covid-19 emergency declaration next month, it’s still going to hold on to some pandemic-era powers. The Department of Health and Human Services gave governors a heads-up on Friday that it is planning to keep pharmacists’ ability to administer Covid-19 and flu vaccines past the end of the public health emergency.

Vaccines 337

Vaccines 337

ALiEM - Pharm Pearls

APRIL 10, 2023

The patient is a 3-month-old, full-term male who presents with a rash on his head. The rash started one day prior to presentation on his forehead and spread to the rest of his head. Today, it developed a central clearing with surrounding redness. He has a history of sensitive skin since birth with patches of eczema and cradle cap. He treats these with Aquaphor and Honest Co.

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PharmaVoice

APRIL 13, 2023

The COVID-19 pandemic highlighted an ongoing problem of vaccine hesitancy undermining public health efforts. One way pharmas can help is to change the narrative.

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Vaccines 148

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Pharmacy Management

Pharmafile

APRIL 14, 2023

Pharma giant Eli Lilly’s Biologic Licence Application (BLA) for its bowel disease drug has been declined by the FDA over concerns about the proposed manufacturing of the drug. However, concerns weren’t expressed over the clinical data package, safety or label for the medicine. Mirikizumab was hoped to become a new drug treatment for ulcerative colitis (UC), a condition where abnormal reactions in the immune system cause inflammation in the inner lining of the colon.

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Packaging Labelling Immunity Immunization 118

STAT

APRIL 12, 2023

Prior to the early 20th century, America had no regulation of medications or food additives. Formaldehyde was used to preserve meat, morphine was included in infant “soothing syrups,” and marketing, not science, drove the promotion of tonics and medications. The 1906 Food and Drug Act was the first in a series of consumer protection laws focused on setting standards for safe and effective medications and food additives.

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European Pharmaceutical Review

APRIL 13, 2023

Psychedelics are a class of psychoactive substances that produce temporary changes in perception, mood and cognitive processes. 1 Some psychedelics are found in nature, including psilocybin, a naturally occurring molecule found in almost 150 species of mushrooms which turns into psilocin once ingested, causing psychedelic effects. Other psychedelics are man-made, such as lysergic diethylamide (LSD), which was first synthesised in 1938 by Albert Hofmann at a laboratory in Switzerland. 2 LSD is wi

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Biosimilars Pharmaceutical Companies Pharmaceutical Companies 117

PharmaVoice

APRIL 14, 2023

A serial entrepreneur, futurist and industry disrupter, the VP of clinical development and digital health is always on the quest to build a “better mousetrap.

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BioPharma Dive

APRIL 10, 2023

Drugmakers are announcing job cuts at a faster clip so far this year than during the same period in 2022, suggesting that fundraising remains difficult.

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STAT

APRIL 13, 2023

Like many cardiologists, Manuela Thienel spends most days in the chlorinated, temperature-controlled halls of a large hospital. But one week in February 2019, her work brought her to a snowy Swedish forest, where she stood shuddering in a winter coat, looking on as veterinarians and rangers walked into a bear den to drug a hibernating bear and retrieve its blood.

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Hospitals 285

Pharmaceutical Technology

APRIL 14, 2023

Ghana’s Food and Drug Authority (FDA) has approved R21/Matrix-M malaria vaccine in children aged 5 to 36 months, marking the first regulatory clearance for the University of Oxford-developed vaccine in any country in the world. Serum Institute of India (SIIPL), manufacturer and licence holder of the vaccine, has been notified of the registration by Ghana’s FDA.

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Vaccines Immunity Immunization 111

European Pharmaceutical Review

APRIL 10, 2023

The high reliability of matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometry (MS) systems for microbiological identification offer an alternative to serological-based methods, according to a review by researchers. “New technologies for the accurate and rapid identification of bacteria are essential in various fields of applied microbiology.

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BioPharma Dive

APRIL 8, 2023

The decision imperils access to the drug more than two decades after its U.S. approval, and could carry consequences for the FDA’s authority over prescription medicines.

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STAT

APRIL 12, 2023

Last fall in STAT, Matt Herper questioned whether the biomedical research enterprise is really laying the necessary groundwork to gain the full benefit of innovation in “biology’s century.” “The biggest looming problem is that… new technologies in biology [could] outpace our ability to assess them,” he observed.

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Pharmaceutical Technology

APRIL 13, 2023

Dyadic International has announced expansion of a licence agreement for its C1-cell protein expression platform with South African consortium Rubic One Health. The expanded licence will include the development of vaccines and therapeutic proteins beyond Covid-19 for human and animal health markets in Africa. During the Covid-19 pandemic, vaccination rates of many countries in Africa were significantly trailing the rest of the world.

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Vaccines 111

Pharmacy Joe

APRIL 12, 2023

In this episode, I’ll discuss the dose of methylene blue for the treatment of acquired methemoglobinemia. Episode 808: How To Dose Methylene Blue For the Treatment of Acquired Methemoglobinemia Subscribe on iTunes , Android , or Stitcher Acquired methemoglobinemia is typically a reaction to medications. The ferric hemes of methemoglobin are unable to bind oxygen therefore causing a functional anemia.

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Inpatient 105

BioPharma Dive

APRIL 11, 2023

The shot appears to generate an immune response that matches or exceeds existing vaccines, but investigators aren’t yet sure how well it can prevent illness.

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Vaccines Immunity Immunization 109

STAT

APRIL 12, 2023

NEW YORK — Michael J. Fox was sitting in his Upper East Side office surrounded by Emmys and an Oscar — one he received not for his acting but for his Parkinson’s philanthropy. (“Humanitarian stuff,” he said nonchalantly.) He wore blue trousers and a T-shirt, and Adidas sneakers with no socks. His hair, years ago always perfect, was a bit disheveled, and he was in constant movement in his chair, a hallmark of the Parkinson’s disease that has defined

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Pharmaceutical Technology

APRIL 14, 2023

Clinical-stage biopharmaceutical company TORL BioTherapeutics has raised $158m in a Series B financing round for advancing the development of new biologics for cancer treatment. TORL BioTherapeutics is a newly formed, US-based company focused on the development of novel antibody-based therapeutics for cancer patients. Led by Goldman Sachs Asset Management, the financing round has also seen participation from Deep Track Capital, Moore Strategic Ventures, Cowen Healthcare Investments, Bristol Myer

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Compounding 105

European Pharmaceutical Review

APRIL 14, 2023

The current progress, challenges and opportunities for achieving stable formulations of nucleic acid (NA) therapeutics with novel drug delivery systems (DDSs) has been discussed in a paper published in Pharmaceutics. Over the past decade, the impact of nucleic acid (NA)-based biopharmaceuticals has been facilitated by breakthroughs associated with high-end manufacturing and pharmaceutical drug delivery.

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Dosage Vaccines 100

BioPharma Dive

APRIL 11, 2023

The pharma, which recently retreated from cell therapy research, will pay Adaptimmune about $37 million as part of an agreement to return rights to two cancer treatments.

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STAT

APRIL 12, 2023

Pacemakers, relied upon by many patients with irregular heart rhythms, are not built for children. Scrambling up trees, hanging from monkey bars, and even the simple act of growing make the device more likely to fail.  Roughly 1 in 15,000 children are born with congenital heart block , which causes an abnormally slow heart rate. The condition leads to lightheadedness, shortness of breath, and in serious cases, heart failure.

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Pharmaceutical Technology

APRIL 14, 2023

Ginkgo Bioworks (Ginkgo) and the Wisconsin Alumni Research Foundation (WARF) have collaborated to discover next-generation GD2 CAR T-cell therapies to treat solid tumours. WARF is the patenting and licensing organisation for the University of Wisconsin–Madison in the US. Ginkgo will partner with researchers from Wisconsin-Madison to discover new and improved GD2 CAR designs with improved persistence, fitness and proliferation.

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PhRMA

APRIL 12, 2023

Recent district court rulings set an alarming precedent that calls into question the authority of the U.S. Food and Drug Administration (FDA) to determine the safety and effectiveness of new medicines.

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PharmaTech

APRIL 11, 2023

A document signed by members of more than 400 companies and investment firms decries the decision made by a federal judge concerning mifepristone, a medication used in abortions.

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Documentation 98

STAT

APRIL 10, 2023

When Jeannette Cleland learned earlier this year that she could get chemotherapy at home, after dropping a particularly toxic medication, it seemed like good news. But then Cleland, a 44-year-old Minneapolis event planner who has stage 4 pancreatic cancer, did the math. She added up the time involved: waiting for a nurse to arrive to draw her blood; waiting for a courier to pick up her blood; waiting for another courier to drop off the chemotherapy drugs; waiting for a nurse to arrive to co

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Chemotherapy 246

Pharmaceutical Technology

APRIL 11, 2023

The US government is reportedly investing more than $5bn in a programme to accelerate the development of new Covid-19 vaccines and treatments. Dubbed Project Next Gen, the new effort will follow an approach similar to that of Operation Warp Speed, which developed and delivered vaccines to Covid-19 patients in 2020 by forming private-public partnerships for the rapid development of new vaccines.

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Drug Patent Watch

APRIL 13, 2023

Annual Drug Patent Expirations for ZOSYN+IN+PLASTIC+CONTAINER Zosyn In Plastic Container is a drug marketed by Wyeth Pharms and is included in one NDA. It is available from two suppliers. There… The post New patent expiration for Wyeth Pharms drug ZOSYN IN PLASTIC CONTAINER appeared first on DrugPatentWatch - Make Better Decisions.

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Digital Pharmacist

APRIL 10, 2023

Americans are some of the most stressed people in the world, according to studies. Many factors can contribute to stress and at times it can be difficult to manage them. As pharmacists, we are pulled in many directions throughout the day and this coupled with our day-to-day demands can lead to a high-stress environment. In today’s blog, we will discuss stressors for pharmacists and ways we can help to mitigate them. % of workers in the US suffer from work-related stress (Source: American I

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Pharmacy Management HIPAA Communication 98