Sat.Oct 08, 2022 - Fri.Oct 14, 2022

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Opinion: Maternity care in the U.S. is in crisis. It’s time to call the midwife

STAT

After pushing for several hours, my patient looks exhausted but happy, clutching her seconds-old newborn to her chest. As I help her put her baby to breast for the first time, she isn’t thinking about anything other than the tiny human blinking up at her. As well she shouldn’t.

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The digital therapeutics revolution is happening and Big Pharma is buying in — with caution

PharmaVoice

Companies like Pfizer, Novartis, Sanofi and BMS are diving into the world of digital therapeutics while recognizing the limitations of the young field.

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Trending Sources

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Robotic capsule could replace injected biologics

European Pharmaceutical Review

Scientists at MIT have demonstrated that a novel robotic capsule could potentially replace conventional biologic injection methods by tunnelling through the intestinal mucus barrier to deliver insulin. The research, published in the journal Science Robotics described how the new drug delivery system can transport large protein and small-molecule drugs, like vancomycin, an antibiotic peptide.

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Janssen leads effort to cut waste in digital health devices

pharmaphorum

A consortium of industry and academic groups – led by Johnson & Johnson’s pharma division Janssen – has been set up to tackle the environmental impact of digital health products, specifically aimed at minimising waste that could end up in landfill. The Digital Health in a Circular Economy (DiCE) group was formed earlier this year with the aim of developing ways to “design, collect, directly reuse, refurbish, remanufacture, and recycle digital health devices.” The programme

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Human neurons implanted in a rodent’s brain lead a rat to water — and make it drink

STAT

The scientist flicked on a laser, filling the rat’s brain with blue light. The rodent, true to its past two weeks of training, scampered across its glass box to a tiny spout, where it was duly rewarded with a drink of water. From the outside, this would appear to be a pretty run-of-the-mill neuroscience experiment, except for the fact that the neurons directing the rat to its thirst-quenching reward didn’t contain any rat DNA.

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Woman of the Week: HBA’s Nikki Jones

PharmaVoice

As the Healthcare Businesswomen’s Association’s first chief people and DEI officer, Jones is poised to tackle pay gap inequity, systemic gender bias and leadership barriers impeding women of color.

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More Trending

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Merck and Moderna partner to develop and sell cancer vaccine

Pharmaceutical Technology

German pharmaceutical firm Merck has extended its partnership with Moderna to jointly develop and sell mRNA-4157/V940, an investigational personalised cancer vaccine (PCV). In 2016, the companies entered a strategic partnership to develop novel messenger RNA (mRNA) based PCVs. They subsequently expanded the collaboration to include the development of antigen mRNA cancer vaccines in 2018.

Vaccines 115
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Which diet and health habits are backed by science? Now there’s a tool for that

STAT

Does eating red meat increase one’s risk of heart disease? Would eating more vegetables help? Is leaving high blood pressure untreated really a death wish? The answers might vary, depending on who a person asks, which friend or TikTok nurse, and when. Researchers at the University of Washington want to make it easier to find current, evidence-based health advice.

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Patient insights data

PharmaVoice

While there are many sources of real-world evidence, there’s growing interest and focus on capturing patient generated insights to capture a more specific level of understanding for a given therapy.

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RemeGen receives ODD for myasthenia gravis treatment

European Pharmaceutical Review

RemeGen has announced that the US Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) for its proprietary novel fusion protein Telitacicept (RC18) for the treatment of myasthenia gravis (MG). Telitacicept is a proprietary novel fusion protein from RemeGen to treat autoimmune diseases. It is constructed with the extracellular domain of the human transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) receptor and the fragment crystallisable

Immunity 113
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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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AstraZeneca’s intranasal COVID vaccine fails first clinical test

pharmaphorum

An intranasal formulation of AstraZeneca’s widely-used COVID-19 vaccine Vaxzevria has failed at the first hurdle, after results from a phase 1 trial found it was unable to stimulate a strong immune response to the virus. The 30-subject study – funded by AZ and published in the Lancet journal eBioMedicine – tested two strengths of the current formulation of the vaccine administered as a nasal spray, with half the group receiving a second intranasal dose 28 days later, and half getting a reg

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‘It still prevented cancers’: Experts discuss furor over colonoscopy study and dissect the nuances

STAT

On Sunday, the New England Journal of Medicine published the interim results of a landmark trial examining the effect of inviting people to colonoscopy screening. The paper, which STAT covered , exploded across medical media and ignited debate over the trial’s results, how to interpret those results, and the popular coverage of the study. The frenzy resulted over the trial’s main finding — which is that offering colonoscopies to people did not reduce cancer deaths within a 1

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Coming out of stealth, RIGImmune aims to catch up with ever-mutating viruses

PharmaVoice

President Susan Sobolov discusses how the startup is building on the work of two powerhouse Yale scientists to advance candidates for viruses — and beyond.

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Patient recruitment completed in Tourette syndrome study

Pharma Times

Research has demonstrated a strong safety prolife and reduced tics among participants

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How the food allergy sector is benefitting from health tech’s recent boom

pharmaphorum

For the 32 million individuals in the US with food allergies, more research into symptoms, causes, and treatments has been long sought after, but historically underfunded. The National Institutes of Health (NIH), which oversees disease research, has a total annual budget equivalent to $120 per person, with only $0.19 per person being spent on food allergy research.

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Faster brain imaging technique seems to overcome limitations of current MRI scans

STAT

Research often proceeds in a logical progression, new studies building upon a detailed understanding of the underlying processes revealed by earlier work. But a new brain imaging technique that can directly track the activity of neurons emerged from one of academics’ favorite questions: “What would happen if we tried doing it this way?

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Harnessing the creative energy of California, Alto is advancing a novel approach to psychiatric meds

PharmaVoice

After making the leap from academia to the world of biotech, CEO Dr. Amit Etkin is hoping to shift the treatment paradigm for neurological conditions.

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Positive results from trial of Arecor’s insulin candidate AT247

Pharma Times

Therapy demonstrates significantly accelerated insulin absorption and early exposure

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Eureka Institute to show what translational medicine can do for digital health

pharmaphorum

It’s no secret that the healthcare system is made up of a panoply of diverse stakeholders, each with their own priorities, incentives, and motivations. Bringing those stakeholders together is an oft-lauded goal, but it’s proved easier said than done. The Eureka Institute, a Syracuse, Italy-based non-profit, is focused on addressing this disparity by providing education, research, and advocacy around the field of translational medicine.

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Maternity care ‘deserts’ on the rise across the U.S., report finds

STAT

The home birth had been going well, with the baby having been delivered safely, when midwife Lauren Genter noticed that the mother was losing more blood than normal. The family was Amish and didn’t have a phone in the house, so Genter took her cellphone to the one window where she had spotty service to call for an ambulance. She was able to keep the mother stable while they waited.

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Robotic pills could open a world of possibilities for the biologics market

PharmaVoice

As the oral biologic market heats up, Rani Therapeutics is looking to dominate the field with its robotic pill for treatment of chronic conditions.

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AlzeCure demonstrates disease-modifying effects of NeuroRestore ACD856

Pharma Times

Data from the study shows that ACD856 has a potential neuroprotective effect in a cellular mode

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Using S. boulardii for Hashimoto’s

The Thyroid Pharmacist

I first learned about S. boulardii as a young pharmacist. It is a beneficial yeast (also known as a probiotic yeast) that is often recommended to people who take antibiotics, to counteract the gut imbalance that can occur when antibiotics kill off our “good” bacteria, in addition to any of the pathogenic bacteria they were initially taken to kill. This particular probiotic is thought to be most effective in restoring dysbiosis from antibiotics because, in contrast to most probiotics which are ba

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In gold-standard trial, colonoscopy fails to reduce rate of cancer deaths

STAT

For decades, gastroenterologists put colonoscopies on a pedestal. If everyone would get the screening just once a decade, clinicians believed it could practically make colorectal cancer “extinct,” said Michael Bretthauer, a gastroenterologist and researcher in Norway. But new results from a clinical trial that he led throw confidence in colonoscopy’s dominance into doubt.

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New partnership may give MDMA an edge in the psychedelics space

PharmaVoice

While LSD and psilocybin steal the spotlight, drug developers are also exploring MDMA for a wide swath of neurological illnesses.

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Liverpool city region wins government status for vaccine discovery

Pharma Times

DIT to showcase Liverpool city region’s life sciences expertise which will also include manufacturing

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Top 10 Ways to Celebrate Pharmacy Week

Digital Pharmacist

Pharmacy Week is almost here and what an exciting time is it! Pharmacy Week takes place during the 3 rd week of October each year. According to ASHP, this week is “a time to recognize the powerful impact you make on your patients”. No better time to celebrate your pharmacy teams and their impact as well as your incredible patients than Pharmacy Week. .

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STAT+: Documents detail how pharmacy giants Walgreens, CVS, and Walmart failed patients in the opioid epidemic

STAT

In 2011, Walgreens executives were under pressure. Amid a growing addiction crisis, and with the country already awash in prescription painkillers, the federal government was demanding accountability from the pharmacy giant for filling thousands of opioid prescriptions written by doctors in suspiciously large quantities.   Scrambling for a solution, the company’s leadership traded ideas for new ways of ensuring its pharmacies would stop filling medically illegitimate prescriptions.

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Where the CEO of ADC Therapeutics sees ‘huge potential’ in the tech beyond oncology

PharmaVoice

The “magic bullet” approach of ADCs has been a breakthrough in cancer care — but this excitement could be just the beginning.

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UK economy shrinks by 0.3% on back of manufacturing slump

The Guardian - Pharmaceutical Industry

August GDP data from ONS gives strong signal that UK is entering recession Business live updates: UK economy shrinks in August Britain’s economy shrank by 0.3% in August from July, hit by a slump in manufacturing and by maintenance work that slowed the oil and gas sector, official data showed. Giving a strong signal that the UK is entering a recession , the Office for National Statistics said manufacturing declined by 1.6% while the cost of living crisis appeared to hit hotels, restaurants and t

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Strep & Flu Testing at the Pharmacy

Digital Pharmacist

It has been estimated that more than 78 million visits to the physician office over a 10 year period are for acute pharyngitis, and among those 15% to 30% of cases originated from Group A Streptococcus (GAS) and 2% from Influenza. In order to reduce the number of hospitalizations due to pharyngitis and reduce financial burden for patients, one way is to get access to testing and get treated in the earlier stage of the infection.

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A doctor’s humbling journey treating long Covid: ‘The second we think we know what we are doing, we fall flat on our face’

STAT

I first met Wes Ely in 2016, when I wrote about ICU delirium and Ely’s attempts, as a critical-care physician at Vanderbilt University Medical Center, to urge fellow health care workers to rethink the use of heavy sedation in ICUs. His research was an attempt to limit the crippling cognitive and physical impairments he saw develop in many critical-care patients long after they left the hospital, something he came to call post intensive care syndrome, or PICS.

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Citius Pharmaceuticals sees golden opportunities in late-stage specialty assets

PharmaVoice

CEO Leonard Mazur explains how the company’s hoping to unlock the potential of its varied pipeline.

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Keeping it Simple

PharmExec

Bristol Myers Squibb commercial head Chris Boerner believes a straightforward formula is the best formula in advancing innovation and developing talent in today’s complex healthcare climate—an approach he roots in authenticity and “not over engineering,” whether tackling business or culture.

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Wellcome funds work on regulating digital mental health tools

pharmaphorum

An explosion of digital mental health tools being offered for sale has presented regulators with a problem – how should they be classified and assessed for safety or efficacy? Wellcome has provided funding in the UK to help answer that question. The healthcare charity is providing £1.8 million (around $2 million) in financial support for UK health technology assessment (HTA) agency NICE and medicines regulator MHRA to develop guidance on “appropriate, risk-proportionate regulation of digit

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