Sat.Dec 30, 2023 - Fri.Jan 05, 2024

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Biopharma dealmaking: predictions for 2024

European Pharmaceutical Review

The past 12 months has seen significant growth in global mergers and acquisitions (M&A) within the biopharma sector. This activity is expected to continue in 2024, with increasing need for biopharma to access innovation through collaboration and dealmaking to offset looming patent challenges. “In 2023, total life sciences deal value increased by 34 percent to $191 billion.

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Opinion: Insurance companies are forcing psychiatrists like me to stop accepting their coverage

STAT

“I’m sorry, but I’m unable to take on new patients at this time.” I’ve said that line hundreds of times in the 15 years since I started my solo private practice in psychiatry. I feel terrible each time I say it. Someone on the other end of the phone is suffering and has taken the difficult step to call for help — probably multiple calls, given the longstanding shortage of psychiatrists — and yet I added to their hopelessness.

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Prescribing Success: Dr. Linda Gutierrez-Miller’s Journey to Impactful Clinical Pharmacy and Inspiring Resilience!

Pharmacy Is Right For Me

“How can I make the biggest difference in the lives of others? How can I help the most people?” These questions often cross the minds of students as they navigate the labyrinth of career choices. Dr. Linda Gutierrez-Miller, one such student, embarked on a journey to answer these questions, ultimately choosing a career path that aligns with her goals of making a substantial impact and aiding a diverse range of individuals—clinical pharmacy.

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In the post-pandemic era, three players still dominate the infectious disease market

PharmaVoice

Although three companies dominate the space, emerging infectious disease focus areas and a handful of other key players are augmenting the market.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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EM Match Advice 42: Mid Interview Season Check-In

ALiEM - Pharm Pearls

Dr. Sara Krzyzaniak (podcast host and Stanford University PD) and Dr. Michelle Lin (ALiEM Founder/UCSF) are joined by Dr. Aaron Kraut (University of Wisconsin PD) in this insightful, rapid-fire, practical episode through the lens of experienced residency program directors. What does the Electronic Residency Application Service (ERAS) preliminary data show just far for the 2024 residency application season?

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How opioid overdoses in public restrooms led an electrician to invent ‘safe bathrooms’

STAT

First, a light starts to flash. Then a high-pitched siren starts to blare. Then come the sounds of nearby doors being flung open, and the frantic footsteps of doctors and nurses rushing toward a restroom at the end of a hallway. They’re in a hurry for good reason. These distress signals have a specific meaning: Somebody in the bathroom is overdosing.

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Alzheimer’s research is hot, but successful patient recruitment will determine its future

PharmaVoice

Key strategies for bringing more patients into the clinical trial fold.

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Infant formula recalled over contamination fears

The Pharmacist

Two Reckitt infant formulas have been recalled over concerns that they are contaminated with the bacteria Cronobacter sakazakii. Batch ZL3F7D of Nutramigen LGG Stage 1 Hypoallergenic Formula 400g and batches ZL3FAA and ZL3FDM of Nutramigen LGG Stage 2 Hypoallergenic Formula 400g may have been contaminated with the bacteria, the Food Services Authority (FSA) has said. […] The post Infant formula recalled over contamination fears appeared first on The Pharmacist.

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STAT+: Texas taxpayers wanted to help the poor get health care. Instead, they’re funding a medical school at a wealthy university

STAT

AUSTIN, Texas — Eleven years ago, local officials promised voters in the most liberal county in Texas that if they supported tens of millions of dollars in new taxes, they’d deliver a win-win scenario: Austin would get a new medical school, and poor people navigating the health care system in a state with the country’s worst uninsured rate would get more health care services.

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A new startup from Feng Zhang and an ex-Illumina executive zeroes in on the epigenome

BioPharma Dive

Moonwalk Biosciences, the latest biotech cofounded by the gene editing scientist, joins other startups aiming to alter gene expression without changing DNA.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Pharma’s financial market will be a tale of two cities in 2024

PharmaVoice

What can the industry expect in 2024? Some bright spots, a few bumps and “immaculate disinflation.

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Why amplifying the patient voice is crucial to clinical trial success

pharmaphorum

Amplifying the patient voice is essential for the success of clinical trials. Learn why it is crucial for patient engagement, recruitment, and overall trial success, and how it can address challenges such as transportation and financial barriers.

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Allen Institute CEO Rui Costa on mapping the brain and paying early-career scientists decent salaries

STAT

Mapping the billions of cells that make up the brain is a task mammoth enough to keep hundreds of researchers across continents busy for years. But it’s just one of several ambitious projects the Allen Institute is helping tackle. The nonprofit research institute, based in Seattle, was founded in 2003 by Microsoft co-founder and philanthropist Paul Allen to go after big and basic scientific questions.

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Cross-party MPs sound alarm over pharmacy pressures

The Pharmacist

MPs have written to pharmacy minister Dame Andrea Leadsom to raise concerns about the pressures facing community pharmacy. In a letter sent last month, they called for the government to urgently consider creating a new core funding model, and to focus on implementing and developing Pharmacy First, as well as other clinical service areas. These […] The post Cross-party MPs sound alarm over pharmacy pressures appeared first on The Pharmacist.

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Allogene to shift strategy in bid to reposition CAR-T

BioPharma Dive

The company plans to restructure and will start a new late-stage study testing whether its “off-the-shelf” therapy can boost cure rates when used early on.

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PulmCrit – Validation of my model for converting VBGs to ABGs

EMCrit Project

background and general concept My research project in fellowship was the construction of a mathematical model to convert VBG values into ABG values. The fundamental concept for the model was pretty simple: we can approximate the respiratory quotient (RQ) of tissue in the hand as being constant. This indicates that changes in oxygen content and […] EMCrit Project by Josh Farkas.

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STAT+: Goldman Sachs launches $650 million fund for life science investments

STAT

Investment bank Goldman Sachs is jumping into the biotech world after raising $650 million to invest in privately held startups. The bank announced Wednesday that it has closed its first-ever life sciences fund, called West Street Life Sciences I. The plan is to invest the money in genetic medicine, cell therapies, immunotherapies, synthetic biology and artificial intelligence startups, as well as diagnostics and life science tools companies.

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Genomics workforce group to recruit new members

The Pharmacist

NHS England’s pharmacy workforce group for genomics is seeking to recruit five new pharmacist or pharmacy technician members. Both pharmacy professionals with specialist expertise in genomics and those in the early stages of their career can apply, with expressions of interest to be submitted by 15 January. Applicants must outline any genomic medicine experience, qualifications […] The post Genomics workforce group to recruit new members appeared first on The Pharmacist.

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FDA authorizes Florida to import drugs from Canada

BioPharma Dive

The clearance is a major shift for the agency, which described its decision as a “first step” in allowing Florida to bulk purchase lower-cost Canadian medicines.

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The race for obesity drug assets heats up

pharmaphorum

The race for obesity drug assets is becoming more intense as pharmaceutical companies strive to develop effective treatments for weight loss. This article explores the efficacy, potential sales, and market trends in the field of obesity drugs.

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Baby monitor videos yield evidence for long-suspected link between seizures and unexplained toddler deaths

STAT

The baby monitor didn’t go off. Any sound or motion in the twins’ room was supposed to set off an alarm — but in the wee hours of Nov. 27, 2022, Katie Czajkowski-Fell and Justin Fell weren’t woken up. They’d gotten it because of Hayden’s febrile seizures. These are common, generally nothing to worry about, the doctors said.

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Universities join forces to tackle pharmacist shortage in South West England

The Pharmacist

The universities of Bath and Plymouth have teamed up to offer more pharmacist training places at an additional location, to combat workforce shortages that particularly affects the South West of England. From this September, pharmacy students will be able to undertake the University of Bath MPharm course at the University of Plymouth, as well as […] The post Universities join forces to tackle pharmacist shortage in South West England appeared first on The Pharmacist.

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FDA ends busy year with three drug rejections

BioPharma Dive

Amgen had its bid for full approval of the cancer drug Lumakras turned back by the agency, which also issued complete response letters to Zealand Pharma and Merck & Co. in December.

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MHRA’s post-Brexit mutual recognition framework goes live

pharmaphorum

The UK medicines regulator has launched its mutual recognition framework for authorising medicines in a move that it says will help to bring new drugs to patients in the UK more quickly.

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Cardiac psychologists are pushing to protect heart patients’ often-overlooked mental health

STAT

Margery Quackenbush was attending a board meeting of the nonprofit where she served as executive director when she felt a sharp, stabbing pain in her chest. As the organization’s president yelled at a board member, Quackenbush — then age 69 — noticed her heart tightening and felt terrified. After that day more than 15 years ago, her cardiologist began a series of tests.

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Covid boosters needed as vaccine protection wanes after six months, finds UKHSA

The Pharmacist

There is a continued need for Covid boosters, according to a Government study, which found they provide significant protection against death but this wanes after six months. Researchers from the UK Health Security Agency analysed data on more than 10.6 million cases of Covid-19 in adults that had been recorded by England’s laboratory reporting system […] The post Covid boosters needed as vaccine protection wanes after six months, finds UKHSA appeared first on The Pharmacist.

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Eli Lilly Announces New Telehealth, Home Delivery Option for Popular Weight Loss Drug

Pharmaceutical Commerce

LillyDirect will facilitate access to medications by connecting patients with independent telehealth providers, bypassing the need to obtain a prescription from a physician and then going to a pharmacy to fill it.

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A look back at 2023: A Benchling biotech breakfast

pharmaphorum

Explore the highlights of the 2023 Benchling biotech press roundtable before Benchtalk London, showcasing cutting-edge software and innovations in the field of biotechnology.

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STAT+: Illumina chief commercial officer leaves to lead liquid biopsy startup Delfi

STAT

Delfi Diagnostics, a startup devising new ways to use routine blood draws to detect early signs of cancer, told STAT Thursday that it has appointed Susan Tousi, chief commercial officer for genomics giant Illumina, as its new CEO. She is the fourth senior executive to leave Illumina since June. Tousi will start next week, just in time for the J.P. Morgan Healthcare Conference , while founding CEO Victor Velculescu will remain on the company’s board to help guide its research programs.

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Government extends GLP-1 RA shortage warning until end of 2024

The Pharmacist

Supply of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) is not expected to return to normal until at least the end of 2024, the government has confirmed. In a patient safety alert published today, the Department of Health and Social Care (DHSC) and NHS England (NHSE) warned prescribers not to switch patients between doses of GLP-1 […] The post Government extends GLP-1 RA shortage warning until end of 2024 appeared first on The Pharmacist.

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Collaboration to develop novel AI-designed oncology therapy

European Pharmaceutical Review

Under a new licensing agreement, Stemline Therapeutics, Inc., a wholly-owned subsidiary of the Menarini Group, gains the global rights to develop and commercialise a novel, small molecule KAT6A inhibitor. This treatment has potential for hormone sensitive cancers such as breast cancer, and other oncology indications. The therapeutic is designed using the artificial intelligence (AI)-platform from Insilico Medicine, the biotech company that is also part of this collaboration.

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Verona cuts $400m loan deal as it preps COPD drug for market

pharmaphorum

Verona Pharma has agreed a new $400 million debt facility with Oxford Finance and Hercules Capital designed to help the company navigate the possible approval and launch of ensifentrine, its therapy for chronic obstructive pulmonary disease (COPD). The Anglo-US company has already tapped $50 million of the funding and can take another $100 million if an ongoing review of ensifentrine by the US FDA results in regulatory approval.

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Opinion: Today’s at-home microbiome testing industry is fraught with snake oil

STAT

The  blue muffin challenge. Food sensitivity tests. Microbiome test kits. Self-help gastrointestinal health is all the rage. Rightly so: One in four Americans is affected by digestive disorders. And we’re all eating worse, sleeping less, and experiencing more stress , leaving our guts feeling twisted.

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James Davies: Medicines should be seen as an investment, rather than a cost

The Pharmacist

The Pharmacist spoke to Royal Pharmaceutical Society (RPS) director for England James Davies towards the end of 2023 to hear what he thinks the future of the profession will look like. As the role of pharmacists and pharmacy technicians continues to evolve, how do you see both professions working well together, and what role does […] The post James Davies: Medicines should be seen as an investment, rather than a cost appeared first on The Pharmacist.

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MHRA authorisation is first endocrine therapy innovation in decades

European Pharmaceutical Review

Korserdu ® (elacestrant) is the first treatment indicated for ER+, HER2- advanced or metastatic breast cancer tumours with ESR1 mutations. The endocrine therapy has been granted a marketing authorisation by the UK Medicines & Healthcare products Regulatory Agency (MHRA). This represents the first endocrine therapy innovation in nearly 20 years. The small molecule treatment is authorised for postmenopausal women, and men, with oestrogen receptor (ER)-positive, HER2-negative, locally advanced

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