Sat.Aug 05, 2023 - Fri.Aug 11, 2023

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What pharma companies are getting wrong about drug repositioning

PharmaVoice

Children’s Tumor Foundation president Annette Bakker is working to teach the industry the crucial difference between drug repurposing and drug repositioning.

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Kim Kardashian sparks debate on the benefits of full-body MRI scans

STAT

The last time Kim Kardashian posted about medical imaging, it was to prove her butt was real. Now, she’s praising its ability to find aneurysms and cancers before they turn deadly. Kardashian’s Instagram post this week about Prenuvo, which sells full-body MRI scans that can run in the thousands of dollars, has renewed a long-running debate about whether the tests are actually valuable or just run the risk of clogging hospitals with false positives and unnecessary follow-ups from we

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PEM POCUS Series: Pediatric Lung Ultrasound

ALiEM - Pharm Pearls

Read this tutorial on the use of point of care ultrasonography (POCUS) for pediatric lung ultrasound. Then test your skills on the ALiEMU course page to receive your PEM POCUS badge worth 2 hours of ALiEMU course credit. Take the ALiEMU PEM POCUS: Pediatric Lung Ultrasound Quiz Module Goals List indications for performing a pediatric lung point-of-care ultrasound (POCUS).

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HIV cell therapy startup Addimmune heads to Wall Street via blank-check merger

BioPharma Dive

The deal will help fund a cell-based treatment that completed Phase 1 testing last year and is designed to provide a “functional cure” for patients with HIV infections.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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In the era of blockbuster obesity drugs, a personalized approach could boost outcomes

PharmaVoice

Ozempic and Wegovy have become household names for weight loss. But obesity is complex, and Phenomix Sciences is looking to bring a personalized medicine approach to the field.

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Bird flu researchers turn to Finland’s mink farms, tracking a virus with pandemic potential

STAT

HELSINKI — It was the quiet that stood out to Tarja Sironen at the fur farm. A specialist in emerging infectious diseases, Sironen has conducted research at fur farms for years. She helped develop a Covid vaccine that was deployed to the country’s mink population during the pandemic. She knows the industry well.

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More Trending

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Bridging the Divide: Medical's Omnichannel Momentum

PharmExec

How pharma medical affairs and commercial teams are synchronizing their capabilities to boost omnichannel marketing strategies and better understand customer engagement needs.

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Pharma’s rocky love affair with oxytocin

PharmaVoice

Although research on using oxytocin as a drug has varied, Tonix Pharmaceuticals is banking on the “love hormone” to treat autism, anxiety and more.

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STAT+: Telehealth companies are driving a large share of weight loss drug prescriptions, claims data suggest

STAT

As a new class of obesity medications has soared in popularity, so have the online outlets built to get them in the hands of patients. A new analysis of claims data from Trilliant Health suggests that collectively, telehealth companies — in particular, cash-pay options that market directly to consumers — could account for nearly half of the patients with insurance claims for GLP-1 prescriptions in 2022.

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Antibiotic Interactions: Combinations to Avoid for Safe Medication

FADIC

Antibiotic Interactions: Avoid for Safe Medication Antibiotic Interactions: Combinations to Avoid for Safe Medication 🧵Some combinations of antibiotics and non-antibiotics that should be avoided💊🚫 1. Flucloxacillin β-lactams are considered to be less prone to drug interactions. Flucloxacillin, however, may ⬇️ tacrolimus concentration, presumably through enzyme induction The same can occur with flucloxacillin and broad-spectrum azoles (vori/posa) LINK 2

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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A Fierce Focus On Unmet Need

PharmExec

From public defender to spearheading the adoption of innovative drugs, Wendy Short Bartie, senior VP and general manager for the hematology and cell therapy division at Bristol Myers Squibb, has remained a steadfast patient advocate—working to fulfill unmet medical needs and bring treatments to as many people as possible.

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A pioneering approach to biotherapeutic antibody discovery

PharmaVoice

Immunotherapy has revolutionized cancer treatment, yet the drug discovery process to develop new biotherapeutic antibodies remains arduous.

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STAT+: Anavex, maker of rare disease drug, keeps shifting the goalposts in its clinical trials

STAT

Anavex Life Sciences is in a tough spot. The serial dissembler of clinical trial results might be forced, finally, to tell the truth when it reads out its next study in Rett syndrome. What sets Anavex apart from all the other biotechs on my radar screen is its habit of shifting the goalposts on clinical trials. Twice last year, first in February and then in December , Anavex announced “positive” outcomes from studies of its drug called blarcamesine — except the results were

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J&J grows cancer drug portfolio with newly approved bispecific

BioPharma Dive

The drug, which will be sold under the brand name Talvey, is now cleared by the FDA to treat multiple myeloma, a blood cancer that J&J has identified as a research priority.

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Pharmacies to be paid for September flu jabs already booked

The Pharmacist

While the flu vaccination service will officially begin in October, pharmacies will still be paid for vaccinating eligible patients who have already booked appointments for September, NHS England (NHSE) has announced. In a letter to flu vaccination providers, NHSE asked that the adult flu vaccination programme commence from October, confirming what it had earlier told […] The post Pharmacies to be paid for September flu jabs already booked appeared first on The Pharmacist.

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Top Ten Tips for Taking the NBSTSA Surgical Technology Exam

Board Vitals - Pharmacist

The journey to becoming a certified surgical technologist is a noble one, filled with dedication, perseverance, and a commitment to excellence. At the heart of this journey lies a crucial milestone – the NBSTSA Surgical Technology Exam. This comprehensive exam contains 175 questions (150 graded) with a pass rate of just 73.7% in 2020. How can you best prepare for the CST exam ?

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How a beautiful symptom of a brutal dementia informs our understanding of creativity

STAT

Carol Spence’s vision is flooded with green. As her brush swoops right and swishes left, she’s first transported to a lush spring meadow, then to the canopies of a rainforest — every stroke bringing her to another verdant utopia. Until she hears her daughter scream, “What are you doing?!

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Q&A: Dr. Daniel Hernandez, Director of Medical Affairs and Hispanic Outreach, Global Healthy Living Foundation

PharmExec

Hernandez details how the non-profit organization advocates for improved access to care at the community, state, and federal levels, and amplifies education and awareness efforts within its social media communities.

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Overdose risk higher when opioid agonists prescribed with other medicines

The Pharmacist

The risk of overdose from prescribed medicines used to overcome drug addiction is higher when patients are taking other medication, according to a new study from the University of Manchester. In some cases, patients were more than twice as likely to be hospitalised with an overdose if they were taking opioid agonists in combination with […] The post Overdose risk higher when opioid agonists prescribed with other medicines appeared first on The Pharmacist.

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GLP-1 Agonists and Gastroparesis

Med Ed 101

There’s always this voice in the back of my head that always cautions me that all that glitters is not gold. After being heralded as the next savior in weight loss by the media, the GLP-1 Agonists/GIP agonists have come under more scrutiny lately in the news. A recent article on CNN details patients who […] The post GLP-1 Agonists and Gastroparesis appeared first on Med Ed 101.

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Study mapping how SARS-CoV-2 disrupts mitochondria suggests a cause for long Covid

STAT

In yet another example of Covid’s seemingly limitless reach into our bodies, new research maps out how the SARS-CoV-2 virus disrupts mitochondria, the power plants in all our cells. The extent of the damage, spanning the lungs, heart, liver, kidneys, and brain, could potentially be one explanation for the lengthy list of persistent symptoms of long Covid , from fatigue to brain fog.

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Artificial Intelligence and Machine Learning in Drug Discovery and Development

Drug Patent Watch

A recent paper published in the journal “Intelligent Medicine” article discusses various aspects of using AI and machine learning in the pharmaceutical industry for drug discovery and development. Results The… The post Artificial Intelligence and Machine Learning in Drug Discovery and Development appeared first on DrugPatentWatch - Make Better Decisions.

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Breaking: NSHE confirms October start for flu vaccinations

The Pharmacist

The NHS adult influenza vaccination programme will begin in October this year instead of on its usual September start date, NHS England (NHSE) has confirmed to The Pharmacist. An NHS spokesperson said that this was in order to ‘maximise protection for patients right across the winter months when it is typically colder, and viruses are […] The post Breaking: NSHE confirms October start for flu vaccinations appeared first on The Pharmacist.

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Emergent to lay off around 400 in pivot away from contract manufacturing

BioPharma Dive

The job cuts will affect “all areas of the company” and, combined with other cost-reduction efforts, lead to annualized savings of over $100 million, Emergent said.

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‘Underwhelming’: NIH trials fail to test meaningful long Covid treatments — after 2.5 years and $1 billion

STAT

More than 2.5 years after the National Institutes of Health received a $1 billion mandate from Congress to study and treat long Covid , the agency has finally launched clinical trials for the often-debilitating condition. But both scientists who study long Covid and patients who have struggled with it say the trials are unlikely to deliver meaningful treatments, suggesting the federal government’s landmark Covid research effort may have been wasted.

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Your Next Leadership Step – Stay Put!

The Honest Apothecary

Have you ever asked yourself this question: “What is the next step in my leadership journey?” It is a good question. Leadership is like climbing a mountain that has no pea or a ladder that has no top rung. Real leaders are generally hungry for the next challenge. They take a tough opportunity, give it their best, then start looking for the next giant to go after.

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Price increase for Atorvastatin 80mg dispensed in July

The Pharmacist

The price concession granted for Atorvastatin 80mg tablets dispensed in July 2023 has increased following a successful appeal from the community pharmacy negotiator. Community Pharmacy England (CPE) has announced the price concession has improved to a rate of £3.91, up from the previously imposed £3.45. And it noted this revised price was ‘high enough to […] The post Price increase for Atorvastatin 80mg dispensed in July appeared first on The Pharmacist.

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Multiple myeloma bispecific antibody granted accelerated approval

European Pharmaceutical Review

The US Food and Drug Administration (FDA) has granted accelerated approval of TALVEY (talquetamab-tgvs) to treat multiple myeloma. Janssen Pharmaceutical Companies of Johnson & Johnson’s first-in-class bispecific T-cell engaging antibody showed an overall response rate (ORR) of over 70 percent in heavily pre-treated multiple myeloma. Based on this data, TALVEY is indicated for adults with relapsed or refractory multiple myeloma who have received at least four prior lines of therapy, includin

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Study shows autistic people are more likely to engage in self-harm — but not because of autism

STAT

Autistic people are at a much higher risk of self-harm leading to emergency care or suicide, according to a recent study published in JAMA Network Open. In particular, the study found, autistic females had an 83% increased risk of self-harm compared to non-autistic females, while for males, the increased risk compared to non-autistic individuals was 47%.

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AI and Drug 'Re-Innovation'

PharmExec

The application of artificial intelligence is steadily finding a home in the pharma industry, but these tools may have unprecedented potential in a more nascent niche along the life sciences continuum: drug development.

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Lilly market value soars on higher sales, obesity drug potential

BioPharma Dive

The Indianapolis drugmaker is now worth more than $500 billion, higher than any other pharmaceutical company, as analysts project lucrative markets for its obesity and Alzheimer's drugs.

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Semaglutide cuts risk of cardiovascular events by 20%, claims manufacturer

The Pharmacist

Diabetes drug semaglutide, marketed as Wegovy, could also reduce risk of cardiovascular events by 20%, its manufacturer has claimed. Novo Nordisk has announced headline findings from its SELECT trial, although they have not yet been published in a peer-reviewed journal. The manufacturer said the trial achieved its primary objective of demonstrating a statistically significant reduction of major […] The post Semaglutide cuts risk of cardiovascular events by 20%, claims manufacturer appeared

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Senators push IRS to launch nonprofit hospital probe

STAT

WASHINGTON — A bipartisan group of senators wants federal tax regulators to probe nonprofit hospitals’ compliance with community benefit requirements, ratcheting up a longtime campaign to hold the tax-exempt providers accountable. Nonprofit hospitals are often subsidized by state or federal funding and exempt from many taxes. In exchange, they are required to aid their surrounding area through public health programs and providing free or discounted care to low-income patients.

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Embracing Programmatic Advertising to Enhance Targeting of HCPs

PharmExec

The precision of programmatic advertising is reshaping the way life sciences brands engage with healthcare professionals, offering enhanced personalization, scale, and optimization in today's digital landscape.

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Doubling Down on Drug Adherence

Pharmaceutical Commerce

Creating a user-centric approach that harnesses both digital tools and behavioral science is key to getting—and maintaining—patients on therapy, and improving clinical, financial, and, ultimately, brand-success outcomes for pharma manufacturers.

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