Sat.Jan 20, 2024 - Fri.Jan 26, 2024

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HPV vaccine study finds zero cases of cervical cancer among women vaccinated before age 14

STAT

A historic new study out of Scotland shows the real-world impact of vaccines against the human papillomavirus: The country has detected no cases of cervical cancer in women born between 1988-1996 who were fully vaccinated against HPV between the ages of 12 and 13. Many previous studies have shown that HPV vaccines are extremely effective in preventing cervical cancer.

Vaccines 364
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J&J’s 2024 strategy will focus on newer meds to offset Stelara’s patent cliff

PharmaVoice

Executives on the healthcare giant’s full-year earnings call highlighted a strong cash position and incremental dealmaking as a way to get past incoming competition.

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SAEM Clinical Images Series: A Rare Case of Purpura

ALiEM - Pharm Pearls

An 88-year-old female presented to the ER with a chief complaint of cough, vague abdominal pain, and a rash. The patient stated that she was started on Cipro eyedrops 1 or 2 days prior to presentation for a possible eye infection. A day prior to presentation she developed a purple purpuric rash on her lower extremities that gradually progressed up her legs, and was present on her buttocks thighs, and lower legs.

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Pharmacy First: Are the floodgates about to open?

The Pharmacist

EXCLUSIVE: With the launch of Pharmacy First in England just days away, an under-pressure community pharmacy sector is torn between welcoming the opportunity and wondering whether patient demand will exceed its capacity. From 31 January, the launch of the highly anticipated service will see patients able to access advice and treatment for seven common conditions […] The post Pharmacy First: Are the floodgates about to open?

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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New chronic Covid study offers insight into which immunocompromised patients are most at risk

STAT

You’ve heard of long Covid, a condition in which the acute infection subsides but troubling symptoms persist. Less well known is chronic Covid: The virus just doesn’t leave, sometimes staying in patients’ bodies long enough to mutate into new variants. This happens to people whose immune systems are compromised, whether through disease or treatment, leaving them vulnerable to infections that last weeks, months, or, in one known case, a year.

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FDA looks to execute ‘largest reorganization in history’ this year

PharmaVoice

What started as an examination of the Human Foods Program has expanded into an agency-wide overhaul.

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Wear PPE for suspected measles, pharmacies told

The Pharmacist

Community pharmacies are among the 'most likely' places to encounter a case of measles, NHS England (NHSE) has warned. And staff have been instructed to 'take appropriate action' and wear personal protective equipment (PPE) to 'stop onward transmission without delay', when dealing with patients with suspected measles. This comes as the UK Health Security Agency […] The post Wear PPE for suspected measles, pharmacies told appeared first on The Pharmacist.

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Rollout of a new malaria vaccine kicks off in Africa

STAT

LONDON — Starting Monday, a new, highly effective malaria vaccine will be rolled out for the first time, as an immunization campaign for children kicks off in Cameroon — a day that global health officials say marked a historic step in the decades-long quest to protect people from one of the world’s deadliest infections. The vaccine drive in Cameroon — the first launch of the vaccine outside of clinical trials and pilot programs — comes as some 20 African countr

Vaccines 363
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PulmCrit hot take: VAP prophylaxis (PROPHY-VAP trial)

EMCrit Project

background: ANTHARTIC trial Prophylaxis against VAP (ventilator associated pneumonia) has is already supported by a few studies in the literature, perhaps most notably the ANTHARTIC trial. That was a multi-center RCT evaluating 48 hours of therapy with ampicillin-sulbactam for patients intubated following cardiac arrest. Antibiotic therapy reduced early-onset VAP, with a trend towards more ventilator-free […] EMCrit Project by Josh Farkas.

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Adverse Event Reports Linked to Counterfeit Ozempic on the Rise

Pharmaceutical Commerce

Concerns regarding hypoglycemia potentially linked to a counterfeit version of Ozempic come at a time in which reports have grown regarding the improper use of GLP-1 receptor agonists for the purpose of cosmetic weight loss.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Pharmacies can start Pharmacy First without an otoscope, says NHSE

The Pharmacist

Community pharmacies that have ordered but not yet received an otoscope may begin offering the Pharmacy First service from 31 January without the otitis media clinical pathway. This comes in response to reports of pharmacy owners struggling to get hold of otoscopes, The Pharmacist understands. NHS England (NHSE) made the concession in a letter to pharmacy contractors […] The post Pharmacies can start Pharmacy First without an otoscope, says NHSE appeared first on The Pharmacist.

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Why many more people are lining up for a flu shot than a Covid vaccine

STAT

America is over the Covid vaccine. Frantic lineups for scarce doses when Covid vaccines first became available have long since given way to widespread indifference. Each new round of boosters has drawn fewer bared arms than the round before it. The Centers for Disease Control and Prevention estimates that, as of Jan. 6, a mere 21.5% of Americans aged 18 and older and 11% of children have been vaccinated with the latest Covid vaccine.

Vaccines 363
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Lilly gene therapy finding puts focus on hearing loss treatment pipeline

BioPharma Dive

An 11-year-old boy born deaf can hear after receiving Lilly's genetic medicine. Others, including biotechs in China and Regeneron in the U.S., are taking aim at the same drug target.

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Legislative Proposals to Tackle Improper Pharmaceutical Patents in the Orange Book

Drug Patent Watch

A recent article published in Health Affairs, delves into the Federal Trade Commission’s (FTC) concerns regarding the inclusion of improper patents in the FDA’s Orange Book by pharmaceutical manufacturers. The… The post Legislative Proposals to Tackle Improper Pharmaceutical Patents in the Orange Book appeared first on DrugPatentWatch - Make Better Decisions.

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Pharmacists concerned Pharmacy First will raise risk of patient abuse

The Pharmacist

Almost nine in 10 employed and locum pharmacists are concerned over the potential damage Pharmacy First may have on an ‘already fragile’ workforce in England, a survey by the Pharmacists’ Defence Association (PDA) has revealed. ‘Many’ among the more than 3,500 staff surveyed also said they were worried the ‘hurried’ upcoming service launch could put […] The post Pharmacists concerned Pharmacy First will raise risk of patient abuse appeared first on The Pharmacist.

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Opinion: Defunding liberal arts is dangerous for health care

STAT

If you want an argument in favor of teaching the humanities, I suggest you ask a medical educator. Across the U.S., the age-old debate about the value of a liberal arts education has seemingly devolved into mortal combat, leaving the humanities in dire straits on college campuses. For example, the Atlantic recently reported on West Virginia University’s decision to gut its humanities programming, and the New York Times wondered whether the liberal arts will exist after the budget cuts hap

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Karuna, Cerevel might be just the start of psychiatry drug M&A

BioPharma Dive

New details of the proposed acquisitions show there were multiple interested buyers, which, according to some analysts, could set the stage for more dealmaking.

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The Omni Advantage: A concise roadmap for change, for the people

pharmaphorum

"The Omni Advantage: Accelerating the Behavioural Change with Omnichannel in Pharma Sales Engagement" is a game-changing book by businesswoman Merhnaz Campbell. Discover insights, strategies, and inspiration for pharma sales field team success.

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Don’t forget clinical capacity of non-prescribers, urges GPhC

The Pharmacist

Recommendations made to the parliamentary pharmacy inquiry include giving greater powers to non-prescribing pharmacists to vary prescriptions and freeing up pharmacists for a more clinical, patient-facing role. Speaking to the health and social care committee (HSCC) last week, the chief executive of the General Pharmaceutical Council (GPhC) suggested that changes needed to be made to […] The post Don’t forget clinical capacity of non-prescribers, urges GPhC appeared first on The Pharmacist

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Opinion: After 20 years in rehabilitation research, my young daughter’s traumatic brain injury transformed my mind and my career

STAT

In the spring of 2020, my almost 4-year-old daughter Livie sustained a severe traumatic brain injury (TBI) when a tree branch fell on her head in our backyard, devastating our whole family. Returning home after five months in the hospital, the real journey began : How do we best care for and support our daughter, who cannot do any daily activities on her own, cannot walk or talk, and has become cognitively impaired?

Hospitals 361
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Obesity care needs greater revolution: GlobalData

Express Pharma

Novo Nordisk and Eli Lilly have been dominating the obesity scene in the past year with the approval of their glucagon-like peptide-1 receptor (GLP-1R) agonists Wegovy and Zepbound. Although medicines with other mechanisms of actions are available on the market, GLP-1R agonists seem to have a greater impact on weight loss and the patient’s life. The development of new weight loss medicines is therefore making great progress, but obesity care needs a much greater revolution, says GlobalData.

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CG Oncology is first biotech IPO of 2024, raising $380m

pharmaphorum

CG Oncology completes the first biotech IPO of 2024, raising $380 million for its oncolytic virus bladder cancer immunotherapy.

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How PCNs can support pharmacists: guidance from a London trust

The Pharmacist

Understanding the responsibilities of a pharmacist employed under the Additional Roles Reimbursement Scheme and ensuring those in post are supported at work have been cited as recent challenges within primary care networks (PCNs) and practices. Here, Krupa Dave and Devinder Kalsi, lead medicines optimisation pharmacists at Central London Community Healthcare Trust (CLCH), share the structured workplan […] The post How PCNs can support pharmacists: guidance from a London trust appeared firs

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Merck CEO refused to testify in Senate because he’s not an expert in drug pricing, Bernie Sanders says

STAT

WASHINGTON — Sen. Bernie Sanders on Thursday jabbed the CEO of Merck for telling congressional staff that he didn’t have the expertise to testify at a Senate hearing on prescription drug prices because he’s a tax attorney. Sanders, who has threatened to subpoena the CEOs of Merck and Johnson & Johnson over their refusal to testify at a hearing on why drug prices are higher in the United States than other countries, told reporters the reasons the companies gave ranged fro

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EMA recommends earlier use of Bristol Myers cell therapy for multiple myeloma

BioPharma Dive

The opinion would allow Abecma to be prescribed after two standard therapies and is the latest sign of CAR-T’s growing use in earlier cancer treatment.

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Trust and treatment: GenAI in life sciences in 2024

pharmaphorum

Discover the role of GenAI in life sciences in 2024. Explore how artificial intelligence and machine learning techniques like GenAI are revolutionising drug development, diagnostics, and research. Learn how industry leaders, including Google, are leveraging GenAI to advance healthcare and enhance patient outcomes.

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Over 500,000 women have accessed HRT through pre-paid certificates

The Pharmacist

More than half a million women in England have accessed hormone replacement therapy (HRT) via the HRT pre-payment certificate (PPC) since its introduction last spring, the government has announced. The PPC scheme was launched on 1 April 2023, reducing prescription costs for eligible HRT items to £19.30 a year. Calculations from the Department of Health […] The post Over 500,000 women have accessed HRT through pre-paid certificates appeared first on The Pharmacist.

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Abortion funds run short of money as demand soars and donations fall

STAT

The head of the Abortion Fund of Ohio had a sinking feeling as she looked at its end-of-year finances last month. The fund had paid out $1.5 million in 2023 to help close to 4,400 patients get abortions — up from 1,175 the year before — and the pace wasn’t sustainable. If the fund didn’t take a pause for a few weeks, she feared it would run out of money and have to close for good.

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Gilead ADC medicine misses goal in closely watched lung cancer study

BioPharma Dive

Trodelvy didn’t outperform chemotherapy in a large study of people with a common lung tumor, a setback that sent company shares down by double digits.

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EU plan for medicine stockpile could worsen UK’s record shortages

The Guardian - Pharmaceutical Industry

Bloc plans to bulk-buy key drugs for all 27 countries, potentially leaving Britain ‘behind in the queue’ The EU is to stockpile key medicines that will worsen the record drug shortages in the UK, with experts warning that the country could be left “behind in the queue”. The EU is seeking to safeguard its supplies by switching to a system in which its 27 members work together to secure reliable supplies of 200 commonly used medications, such as antibiotics, painkillers and vaccines.

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How manufacturing keeps pace with innovation in cell and gene therapy

pharmaphorum

On today’s podcast, host Jonah Comstock is joined by Arturo Araya, EVP of commercialisation at Cellares, a company that is attempting to create a new kind of contract manufacturing organisation for the rapidly crystalizing world of cell and gene therapy.

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Transgender women’s higher risk for HIV is influenced by discrimination, CDC finds

STAT

Transgender women, in particular those belonging to marginalized racial and ethnic groups, have disproportionately high rates of HIV. Yet so far, no standardized surveillance system has collected data that could provide insight into the factors that put people at higher risk for contracting the virus. A survey of transgender women, developed by the Centers for Disease Control and Prevention, aimed to gather and assess behavioral data in relation to HIV prevention and risk for the first time.

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Inhaler Chart – Free PDF!

Med Ed 101

There are so many inhalers on the market for asthma and COPD. LABA, LAMA, and ICS products are getting so hard to keep track of! Honestly, it gets a little overwhelming at times to remember them all by brand name and what category and classification they fall into. My good friend Derek Borkowski is the […] The post Inhaler Chart – Free PDF!

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Entos opens GMP clinical manufacturing facility in US

Pharmaceutical Business Review

The facility is designed to bolster in-house production of drug substances for Investigational New Drug (IND)-enabling studies and trials. This development is pivotal for the company’s proprietary and partnered programme pipelines. The 20,000ft 2 facility includes a lipid formulation production suite and additional suites for mRNA and plasmid DNA (pDNA) manufacturing.

Vaccines 104
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New government strategy targets medicine supply chain disruption

The Pharmacist

A new plan aiming to shore up the UK’s supply of pharmaceuticals has been unveiled by the government. As part of the Department for Business and Trade’s (DBT’s) recently launched Critical Imports and Supply Chains Strategy, an online portal will be set up to allow importers of essential goods – including medicines and healthcare supplies […] The post New government strategy targets medicine supply chain disruption appeared first on The Pharmacist.

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