Sat.Feb 17, 2024 - Fri.Feb 23, 2024

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STAT+: UnitedHealth cyberattack cripples pharmacies’ and hospitals’ ability to process insurance claims

STAT

Hospitals, pharmacies, and other health care providers are getting stuck in an insurance processing logjam after UnitedHealth Group disclosed a cyberattack within a recently acquired subsidiary that serves as a central hub for payments across the industry. The cyberattack and subsequent system outage within UnitedHealth’s Change Healthcare has caught the attention of federal law enforcement agencies.

Hospitals 363
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For Moderna, COVID vaccines were a ‘proof of concept’ — now comes the big test

PharmaVoice

Following Moderna’s COVID-19 vaccine success, therapeutics head Dr. Kyle Holen discusses scaling mRNA development to bring candidates to the finish line in oncology and more.

Vaccines 264
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ACMT Toxicology Visual Pearl: Salt, not Shock

ALiEM - Pharm Pearls

What agent would most likely be responsible for these ECG findings? Cyclobenzaprine Digoxin Flecainide Sotalol Reveal the Answer 3. Flecainide Background [1-3] Flecainide is a class IC antiarrhythmic that binds to the voltage-gated sodium channel of the myocardium, slowing depolarization and prolonging phase 0 of the action potential. In toxicity, bradydysrhythmias, AV nodal blockade, ventricular tachycardia, and rate-dependent QRS widening occur.

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The opportunities and challenges facing rare disease therapies developers

pharmaphorum

Explore the opportunities and challenges facing rare disease therapies developers, including the impact of Rare Disease Day, FDA regulations, and cutting-edge technologies like CRISPR gene therapy.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Florida policy set amid measles outbreak alarms vaccination proponents

STAT

A Florida state policy set amid a measles outbreak in Broward County has vaccination proponents aghast, with many saying it leaves unvaccinated children especially vulnerable to the highly contagious disease. In a letter dated Tuesday about an outbreak at Manatee Bay Elementary School in Weston, located northwest of Miami and west of Fort Lauderdale, the state’s surgeon general, Joseph Ladapo, said that while it is normal policy to tell unvaccinated children to stay home during an outbrea

Vaccines 363
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Value and potential of IoT and AI for chronic diseases treatment

PharmaVoice

A significant growth is predicted for both AI and IoT in healthcare. By 2030, the AI market is expected to reach $187.95 billion USD, while the IoT market is projected to climb even higher to $312.7 billion USD.

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Roche’s Xolair is first medicine for food allergy in US

pharmaphorum

Fast approaching the end of its patent life, Roche and Novartis’ Xolair is going out with a bang, picking up a new approval as the first and only drug therapy for people with food allergies in the US.

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Presidential age debate obscures a simple fact: Some cognitive skills improve as we get older

STAT

When a psychology professor in Michigan looked through his data on interpersonal conflict a decade ago, he discovered something unexpected. The study , which examined differences across cultures and age groups, seemed to show Americans got wiser as they got older. Richard Nisbett was used to research showing poorer mental skills among elderly adults, but his work found they were better at recognizing multiple perspectives, encouraging compromise, and acknowledging the limits of their own knowled

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Behind the breakthrough cancer therapy that just won a historic FDA nod

PharmaVoice

The first-of-its-kind TIL therapy for solid tumors developed by Iovance Biotherapeutics won FDA approval last week.

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Iovance, with approval of ‘TIL’ cell therapy, readies for complex launch

BioPharma Dive

The biotech set a price of roughly $515,000 per patient for its therapy Amtagvi, the first to be approved based on a decades-old technique of using tumor-infiltrating lymphocytes.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Clinical research is about trial and error

pharmaphorum

Clinical research involves trial and error as part of the drug development process. Learn more about how to optimise drug trials and the important role of participants in clinical research.

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Opinion: The Alabama IVF ruling uses faux scientific language to justify a religious position

STAT

Imagine having 15 miscarriages. Maybe you can shrug off the first one or two and keep trying to have children, to create a family. But soon every positive pregnancy test brings a sense of dread, of sad inevitability. Your body becomes your enemy.

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Kite’s next-gen CAR-T aims include quicker production and more disease targets

PharmaVoice

While buzz builds around “off the shelf” CAR-T cell therapies, Kite is staying competitive with a shorter manufacturing turnaround and a focus on broadening applications.

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Frontier gets $80M, Galapagos’ backing to make a better KRAS drug

BioPharma Dive

The startup’s Series C round will support a clinical-stage drug the company thinks could address some of the weaknesses of other KRAS-targeting medicines.

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Transforming clinical data management systems for biotechnology trials

pharmaphorum

Learn how biotechnology trials are transforming clinical data management systems, leveraging machine learning and advanced protocols to enhance efficiency and accuracy in data collection and analysis.

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NIH study of ME/CFS points to immune dysfunction and brain abnormalities at core of long-dismissed disease

STAT

Alison Sbrana was in the belly of an opera when her life changed. Down in the pit, surrounded by fellow orchestra members, she’d been straining to play her flute for half the show. As performers overhead enveloped the audience in arias, Sbrana felt like the Hulk was pulling on the tendons in the right side of her neck. “I begged anybody for meds at intermission,” she said.

Immunity 364
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4 biotechs to watch in 2024

PharmaVoice

A splashy IPO, first-in-class treatments and upcoming approval dates are a few reasons we’ve got our eyes on these biotechs this year.

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UKHSA investigating rise in tuberculosis cases

The Pharmacist

The UK Health Security Agency (UKHSA) is investigating what is behind an 11% rise in tuberculosis cases in England last year. There were 4,850 tuberculosis cases in 2023 compared to 4,380 in 2022, representing a jump of 10.7%, according to provisional data. Even before the Covid-19 pandemic, TB incidence was lower than this, with 4,615 […] The post UKHSA investigating rise in tuberculosis cases appeared first on The Pharmacist.

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Bavarian Nordic gets swift EU review of chikungunya shot

pharmaphorum

Bavarian Nordic will get an accelerated review of its chikungunya vaccine CHIKV VLP at the EMA, as it tries to chase down a lead held by rival Valneva. The Danish pharma group said it is planning to file for approval of its vaccine in the first half of this year, adding the EU regulator’s human medicine committee, the CHMP, has said it will cut the review time from 210 to 150 days under its accelerated assessment procedure.

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Meet the fetal surgeon forging CRISPR’s next frontier: curing diseases in the womb

STAT

SAN FRANCISCO — Outside, the August sun wasn’t yet visible through the thick folds of fog blanketing the San Francisco skyline. Its warmth did not reach the operating room tucked into the sprawling Parnassus Heights hospital complex. In there, the light was all cold and blue fluorescence washing over the sea of scrub caps huddled around an anesthetized young woman on a gurney.

Hospitals 363
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Long-Acting Injectable Cabenuva Found More Effective Than Daily ART at Suppressing HIV in Patients With Adherence Challenges

Pharmaceutical Commerce

Cabenuva (cabotegravir + rilpivirine) showed superior efficacy in maintaining viral load suppression in patients with HIV compared with standard of care daily oral antiretroviral treatment.

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Only half of pharmacists enjoy their work, survey suggests

The Pharmacist

Just 52% of pharmacists enjoy ‘some aspects’ of their work or study, a new wellbeing survey from the Royal Pharmaceutical Society (RPS) and charity Pharmacist Support has found. And nearly nine in 10 pharmacists are at high risk of burnout, the survey suggested, prompting calls to address the underlying factors contributing to poor mental health […] The post Only half of pharmacists enjoy their work, survey suggests appeared first on The Pharmacist.

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AbbVie’s 24-hour Parkinson’s therapy to roll out on NHS

pharmaphorum

Around 1,000 people with Parkinson’s in England will be able to access treatment with AbbVie’s Produodopa, the first therapy delivered by a 24-hour subcutaneous infusion pump

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Small study adds to growing hope CAR-T cell therapy could revolutionize autoimmune disease treatment

STAT

People with autoimmune disorders don’t usually get to talk about a cure. There’s symptom management, hopeful periods of remission often followed by relapses, but rarely a lasting fix for the way their immune system attacks healthy cells. If the immune system is an army, then those with conditions like lupus, multiple sclerosis, or rheumatoid arthritis are often fighting a never-ending war of friendly fire.

Immunity 362
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BioMarin preaches patience amid slow sales for hemophilia gene therapy

BioPharma Dive

The company earned only $3.5 million last year from its Roctavian treatment, far below the $50 million to $150 million range it had forecast eight months ago.

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Codeine linctus reclassified to prescription-only amid addiction risk

The Pharmacist

Codeine linctus has been reclassified to a prescription-only medicine (POM) following concerns it was being used recreationally for its ‘opioid effects’, the Medicines and Healthcare products Regulatory Agency (MHRA) has announced. The cough syrup, which is indicated for dry cough and contains the opioid painkiller codeine, was previously a Pharmacy (P) status medicine.

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FDA starts review of Argenx drug in rare disease CIDP

pharmaphorum

The FDA has said it plans to deliver a decision in June on the use of Argenx’ Vyvgart Hytrulo in rare autoimmune disease chronic inflammatory demyelinating polyneuropathy (CIDP).

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Embryo loss is integral to IVF. Alabama’s ruling equating embryos with children jeopardizes its practice

STAT

An embryo is one of the earliest stages of development of a multicellular organism. But according to the Supreme Court of Alabama, it is a person, too — an unborn child, entitled to the same legal protections as any minor. The court ruled on Feb. 16 that a fertility clinic patient who accidentally destroyed other patients’ frozen embryos could be liable in a wrongful death lawsuit, writing in its opinion that “the Wrongful Death of a Minor Act applies to all unborn children,

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Celebrating Thank a Resident Day 

Board Vitals - Pharmacist

Medical residents play an important role in healthcare, from providing patient care to conducting research and collaborating with healthcare teams. To honor residents and their contributions and sacrifices, we celebrate Thank a Resident Day—a day dedicated to expressing gratitude for these remarkable individuals. What is Thank a Resident Day? Medical residency is a demanding journey filled with long hours, challenging cases, and constant learning.

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New patent expiration for Keryx Biopharms drug AURYXIA

Drug Patent Watch

Annual Drug Patent Expirations for AURYXIA Auryxia is a drug marketed by Keryx Biopharms and is included in one NDA. It is available from one supplier. There are fourteen patents… The post New patent expiration for Keryx Biopharms drug AURYXIA appeared first on DrugPatentWatch - Make Better Decisions.

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Redefining pharmaceutical case processing in the age of AI and automation

pharmaphorum

Discover how AI, automation, and blockchain technologies are revolutionising pharmaceutical case processing in compliance with FDA regulations. Explore the benefits of these advancements in this insightful article.

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Opioid cravings were reduced by anti-obesity drug in small study

STAT

DENVER — The GLP-1 medication liraglutide significantly reduced opioid cravings in a small analysis presented on Saturday. It is the first randomized controlled trial to test anti-obesity drugs against opioid addiction, which kills around 80,000 people in the U.S. each year. Among 20 patients for opioid use disorder, those on liraglutide experienced a 30% reduction in opioid cravings over the three-week study, with this effect evident at even the lowest liraglutide dose, according to

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Pharmacy Delivery: How to Take Your Patient Care to the Next Level

PioneerRx

Many pharmacy trends have taken center stage over the last few years. The long-term care at-home model is rapidly gaining traction. Med sync is becoming less of.

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Analyzing PCSK9 Inhibitor Use in Adults With Cardiovascular Disease

Pharmaceutical Commerce

A cohort study investigates how a change in clinical guidelines, an expanded label, and reduction in drug prices can impact the use of PCSK9 inhibitors as a treatment for atherosclerotic cardiovascular disease.

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Case Study: MGI and Alacris Theranostics

pharmaphorum

This case study explores the collaborative efforts of MGI and Alacris Theranostics in utilising molecular tumour profiling technology for advanced research. Discover the impact of this innovative approach on personalised medicine and treatment strategies.

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