Sat.Dec 16, 2023 - Fri.Dec 22, 2023

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U.S. government spent more on health care in 2022 than six countries with universal health care combined

STAT

American taxpayers footed the bill for at least $1.8 trillion in federal and state health care expenditures in 2022 — about 41% of the nearly $4.5 trillion in both public and private health care spending the U.S. recorded last year, according to the annual report released last week by the Centers for Medicare and Medicaid Services. On top of that $1.8 trillion, third-party programs, which are often government-funded, and public health programs accounted for another $600 billion in spendin

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As ALS research booms, one treatment center finds itself in the spotlight

PharmaVoice

The Healey center is at the front of ALS research and care, earning acclaim from patients, doctors and scientists. Still, the complexities of the disease and of drug development have brought hard-felt losses.

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SAEM Clinical Images Series: Rapidly Spreading Rash

ALiEM - Pharm Pearls

A 19-year-old female with a past medical history of epilepsy presented to the emergency department for evaluation of rash and fever. Two days prior to presentation she began to experience fevers with a Tmax of 103°F. One day before presentation she developed a rash that began on her face and slowly spread down her body, now involving her palms. The patient endorsed associated pruritus and cervical lymphadenopathy with the rash.

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As ALS research booms, one treatment center finds itself in the spotlight

BioPharma Dive

The Healey center is at the front of ALS research and care, earning acclaim from patients, doctors and scientists. Still, the complexities of the disease and of drug development have brought hard-felt losses.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Here are the worst biopharma CEOs of 2023

STAT

Pfizer is this year’s anti-Eli Lilly. If David Ricks is the best biopharma CEO of 2023 , then Pfizer CEO Albert Bourla is, unfortunately, the worst. My annual Worst Biopharma CEO list is typically populated with blockheads and scoundrels. That’s not why Bourla is here. The reason is accountability. Strategic missteps , financial miscalculations, and scientific setbacks have plunged Pfizer into a deep crisis.

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Trends shaping the pharmaceutical industry in 2024

PharmaVoice

Advancements in cloud and AI technology will transform clinical trial efficiency and engagement.

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More Trending

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To fight rare diseases, win the data battle first

pharmaphorum

To effectively combat rare diseases, it is essential to prioritise the collection and analysis of data. This article explores how pharmaceutical companies are leveraging AI and focusing on orphan drugs to tackle rare diseases.

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Pregnant cancer patients often have to terminate. Abortion pill restrictions could make that choice even harder

STAT

WASHINGTON — The patient had already made the agonizing decision to start chemotherapy to address her colon cancer, even though she was 30 weeks pregnant. Within a day, the decisions got harder: her colon perforated, and the pain was excruciating. She would need urgent surgery — and she would have to undergo an emergency C-section immediately.

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What are pharma’s next blockbusters?

PharmaVoice

In a shifting market focused on targeted therapeutics, drugs that generate big profits are still a priority.

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MHRA update on links between aripiprazole and gambling disorder

The Pharmacist

Healthcare professionals prescribing aripiprazole for schizophrenia and bipolar disorder should be alert to the known risk of patients developing addictive gambling, according to a new drug safety update. This reminder about aripiprazole from the Medicines and Healthcare products Regulatory Agency (MHRA) comes after a rise in the number of reports of gambling or gambling disorder it received […] The post MHRA update on links between aripiprazole and gambling disorder appeared first on The

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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A Look Back: The Life Sciences Industry in 2023 and a View for 2024

PharmExec

In the coming year, efficiency and automation will take center stage to maximize constrained resources but balancing sensible financial management with strategic investments will be vital.

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After ‘SNL’ skit on sickle cell CRISPR therapy, advocates cite errors and stereotypes

STAT

Mary Brown was sipping coffee at home in Ontario, Calif., Sunday morning when a friend sent a video clip that ruined her breakfast. It contained a skit from “Saturday Night Live” the night before about the new gene therapies for sickle cell disease. In it, workers gather for an office white-elephant-style gift exchange. A white employee, played by Kate McKinnon, gives a Black employee with sickle cell, played by Kenan Thompson, enrollment in “Vertex Pharmaceutical and CRISPR

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5 noteworthy pharma AI investments in 2023

PharmaVoice

The last year showed how some of the world’s biggest pharma companies are leveraging AI tech.

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Key Parkinson’s protein could offer new potential targets for treatment

Pharma Times

The findings could lead to new treatments to target the mTOR and ease PD symptoms - News - PharmaTimes

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BioNTech wins round in CureVac mRNA patent dispute

pharmaphorum

Shares in CureVac have plummeted after a German court ruled that a patent it holds on mRNA-based COVID-19 vaccines was invalid. The validity of the patent is at the heart of patent litigation between CureVac and fellow German biotech BioNTech and its partner Pfizer, claiming infringement by their Comirnaty coronavirus shot.

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Health data breaches hit an all-time high in 2023

STAT

Odds are, you’ve gotten at least one of the unnerving letters in your mailbox this year: “We’re writing to inform you of a cybersecurity incident,” it might start. It’s the standard notice many health care organizations are required to provide when your protected health information gets exposed — and in 2023, data leaks, hacks, and mishandling led more of them to be delivered than ever before.

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Rise of the chief investment officer: Why the unique role works for Roivant

PharmaVoice

Dr. Mayukh Sukhatme, president and chief investment officer for Roivant, discusses the long game of partnering and business deals in biopharma.

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Cognitive decline in early Alzheimer’s could stem from serotonin loss

Pharma Times

MCI patients had 25% lower levels of serotonin compared to healthy patients Researchers from Johns Hopkins Medicine have suggested that serotonin loss in parts of the brain may play a role in cognitive decline in the early stages of Alzheimer’s disease (AD). Published in the Journal of Alzheimer’s Disease , the study was supported by other contributing scientists from the Johns Hopkins University School of Medicine and the Johns Hopkins Bloomberg School of Public Health.

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Pharmacy contract reform could help integrate care, Lords report finds

The Pharmacist

Pharmacy contract reform is needed to ‘free up’ integration of primary and community care, a House of Lords select committee has been told. In a new report, the Integration of Primary and Community Care Committee has published evidence from various care professionals and academics in an inquiry into the obstacles to providing joined-up healthcare services. […] The post Pharmacy contract reform could help integrate care, Lords report finds appeared first on The Pharmacist.

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Inhaled vaccines could stop Covid infections, monkey studies show

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hey there. Today, we get into why Amy Abernethy is leaving Verily, and why the ongoing reckoning with AI doesn’t necessarily need the voice of Google to chime in. Plus, Jason Mast pops in to give an update on Uniqure’s puzzling approach to presenting trial results.

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This biotech aims to expand the CRISPR toolkit for more disease targets in the liver and brain

PharmaVoice

Arbor Biotechnologies is looking past CRISPR’s recent regulatory wins and into the next stage of gene editing.

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Wearable technology to be offered to thousands with type 1 diabetes in UK

Pharma Times

The condition affects around 270,935 people in England and 16,090 people in Wales - News - PharmaTimes

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Why digital therapeutics (DTx) are effective and safe, but not being prescribed

pharmaphorum

In a new episode of the pharmaphorum podcast, host Nicole Raleigh welcomes Joel Morse, CEO and co-founder of Curavit Clinical Research, and Andy Molnar, CEO of the Digital Therapeutics Alliance (DTA), for a discussion on why it is that digital therapeutics (DTx) are effective and safe, but not being prescribed.

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At a hospital’s teaching kitchen, patients get a taste of food as medicine

STAT

BOSTON — Tony McKoy, Jr. was ready to eat. Black chef’s hat on his head, apron tied on, the five-year-old contemplated his favorite foods, prompted by his mother, Shaquana Peebles. “Pineapple!” he said, savoring its sweetness with his eyes closed while he imagined biting into one. Also, brownies made with black beans. PB&J.

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Pharma breakthroughs: 10 novel drug approvals that made headlines in 2023 

Pharmaceutical Technology

Pharmaceutical Technology outlines some of the biggest US Food and Drug Administration (FDA) drug approvals announced in 2023 that are set to make an impact in the coming years.

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Wearable technology to be offered to thousands with type 1 diabetes in UK

Pharma Times

The National Institute for Health and Care Excellence (NICE) has published final guidance announcing a five-year roll-out of a wearable technology for patients living with type 1 diabetes. The new hybrid closed loop systems have proven to be more effective in maintaining healthy blood glucose levels than standard care. The new guidance followed a review of a clinical trial and real-world evidence by the University of Warwick and Warwick Medical School, funded by the National Institute for Health

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Apixaban Diltiazem Interaction

Med Ed 101

I recently came across a clinical issue in my practice as a consultant pharmacist to assisted living and long-term care facilities. The item in question was how to manage the apixaban diltiazem interaction. Apixaban Diltiazem Interaction Defined Apixaban is significantly metabolized by CYP3A4. This liver enzyme is significantly inhibited by diltiazem.

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STAT+: AAFP’s CEO on how to keep primary care doctors in the field

STAT

In ten years, the United States could be short as many as 48,000 primary care doctors. The specialty is underpaid, to a point that doctors are lobbying Medicare to pay it extra. Even medical residents who chose the specialty are leaving primary care ; some 45% of residents who planned to be generalists changed their mind during their residencies. But R.

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New patent expiration for Glaxosmithkline drug VENTOLIN HFA

Drug Patent Watch

Annual Drug Patent Expirations for VENTOLIN+HFA Ventolin Hfa is a drug marketed by Glaxosmithkline and is included in one NDA. It is available from nine suppliers. There are two patents… The post New patent expiration for Glaxosmithkline drug VENTOLIN HFA appeared first on DrugPatentWatch - Make Better Decisions.

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Cognitive decline in early Alzheimer’s could stem from serotonin loss

Pharma Times

MCI patients had 25% lower levels of serotonin compared to healthy patients - News - PharmaTimes

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Semaglutide Overdose – What Does It Look Like and Why Is It Happening?

Med Ed 101

Semaglutide products have been popping up in news headlines recently, and not because of their continued popularity as effective weight loss medications. Data from poison control centers across the country indicates a drastic increase over the past year in calls related to semaglutide overdose — an increase of over 1500% since 2019 according to a […] The post Semaglutide Overdose – What Does It Look Like and Why Is It Happening?

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STAT+: New Jersey’s telehealth restrictions cut off access to lifesaving care, lawsuit alleges

STAT

Since states started rolling back pandemic-inspired flexibilities that allowed physicians to easily practice telehealth across state lines, virtual health care providers have criticized state-based medical licensure rules as unnecessarily burdensome, expensive, and detrimental to patient care. Now, two of them are arguing in a lawsuit that they can also be unconstitutional.

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Sanofi stops development of lung cancer drug

European Pharmaceutical Review

French pharmaceutical giant Sanofi announced that it is ending the development programme evaluating tusamitamab ravtansine as a monotherapy for certain patients with metastatic non-squamous, non-small cell lung cancer (NSCLC). The decision comes after interim analysis from a Phase III clinical trial , CARMEN-LC03, did not meet a primary end point. CARMEN-LC03, a randomised, open-label study was evaluating tusamitamab ravtansine as monotherapy compared to docetaxel in patients with metastatic non

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NHS expands home-testing kits to detect bowel cancer earlier

Pharma Times

Bowel cancer is currently the third most common type of cancer in England - News - PharmaTimes

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CHMP backs Biogen’s Skyclarys for Friedreich’s ataxia

pharmaphorum

Biogen’s Skyclarys is on course to becoming the first approved medicine for the inherited neurological disease Friedreich’s ataxia (FA) in the EU after it was recommended by the EMA’s human medicines committee.

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