Sat.Feb 11, 2023 - Fri.Feb 17, 2023

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Current treatments for cramps aren’t cutting it. Why aren’t there better options?

STAT

One day last fall, Kiran’s period cramps became so painful they woke her up from a nap. The 19-year-old took some ibuprofen, but found little relief. “The pain was so bad, it felt like someone was punching me,” said Kiran, who asked to be referred to by only her first name for privacy. It felt “like I was giving birth.

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Brian Fox is bringing ‘fresh eyes’ to ad agency Klick

PharmaVoice

Why the recently appointed president of commercial solutions sees near limitless potential to expand Klick’s footprint across the life sciences — and how generative AI is playing a role.

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Trending Sources

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ACMT Toxicology Visual Pearl: Swollen Lips

ALiEM - Pharm Pearls

Photo used with permission The following physical finding would be most consistent with exposure to which of the following? Bee sting Household bleach Isopropyl alcohol Potassium hydroxide Reveal the Answer Answer 4 – Potassium hydroxide Background The markedly swollen lips and drooling in this photo are seen following a caustic ingestion. Potassium hydroxide, also known as potash, is a caustic substance found in fertilizers, cleaning supplies, and some hair products.

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Senate hearing to examine bipartisan reforms to rein in middlemen

PhRMA

Did you know that insurance companies use middlemen — known as pharmacy benefit managers (PBMs) — to decide what medicines people can get and what people pay out of pocket for those medicines?

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: In about-face, Moderna vows Americans won’t have to pay for its Covid-19 vaccine

STAT

In an unexpected shift, Moderna has decided not to ask Americans to pay for its Covid-19 vaccine, a move that follows intense criticism over initial plans to charge $110 to $130 per dose after the company pivots from government contracts to commercial distribution. The vaccine maker released a brief statement that it “remains committed” to ensuring everyone in the U.S. has access to its Covid-19 shot, regardless of whether they have health insurance coverage.

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Pheast’s new CEO on how its ‘don’t eat me’ platform could deliver next-gen precision immunotherapies

PharmaVoice

Jacopo Leonardi’s latest venture is in the burgeoning field of macrophage inhibitors that could target a wide range of cancers.

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More Trending

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Leading innovators in kidney disorder treatment compositions for the pharmaceutical industry

Pharmaceutical Technology

The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: Kidney disorder treatm

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Opinion: The haunting brain science of long Covid

STAT

Matt Fitzgerald used to bike up and down 3,500 feet through the Santa Ana Mountains on three-hour rides just for fun. Now, nine months after being infected with SARS-CoV-2, the virus that causes Covid-19, he can’t muster walking on flat surfaces for 20 minutes without days of exhaustion. “My long Covid life remains terrifying,” he told me.

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Managing for resilience: Passage’s ups and downs in gene therapy

PharmaVoice

After a rocky year, Passage Bio’s CEO is focused on helping the rare disease specialist bounce back.

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Pfizer update Lyme disease vaccine candidate

Pharma Times

Research concerning candidate VLA15 has been discontinued across certain trial sites

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Innovation in immuno-oncology: Leading companies in cancer monoclonal antibody therapy

Pharmaceutical Technology

The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms and the gravity of unmet need, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Immuno-oncology: Leading companies in cancer monoclonal

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STAT+: CRISPR pioneer Feng Zhang launches new genetic delivery startup with $193 million

STAT

Akin Akinc was scouring his email spam box last summer, looking for a missing message, when he stumbled across an unexpected email from a quite recognizable name: Feng Zhang. Zhang, one of the leading scientists in the groundbreaking field of genetic editing, had reached out two days prior to discuss a new company he was working on. Since helping to discover CRISPR-Cas9 — often referred to as molecular scissors that can cut into the genome and edit DNA — Zhang has founded at least

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Survey results: Social influences HCP perceptions and prescriptions

PharmaVoice

Build social strategies into marketing plans to reach HCPs with sharply focused messaging.

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Analytical platform could advance mRNA medicine QC

European Pharmaceutical Review

Tokyo researchers have developed a new analytical platform based on liquid chromatography, mass spectrometry and software analysis that quantifies the structure of messenger RNA (mRNA)-based medicines. The method is an important innovation for quality control ( QC) in production lines. The platform can elucidate mRNA sequences while quantifying ‘capping’ at one end of the molecule and the integrity of the tail on the other, all vital in mRNA pharmaceuticals.

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Weight loss jabs to be sold via high street chemists in England

The Guardian - Pharmaceutical Industry

Appetite suppressant Wegovy, popular with celebrities, seen as breakthrough treatment but not permanent remedy Weekly weight-loss jabs that are popular with celebrities will soon be made available through high street chemists in England, despite controversy over their use. Many people struggle to tackle obesity through diet and exercise alone as they often find they regain the weight that they lose.

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A rare Marburg outbreak sparks a race against time to test vaccines and drugs

STAT

A Marburg fever outbreak in Equatorial Guinea is galvanizing efforts to test drugs and vaccines for a virus that currently has none. But every day counts, warned experts who gathered virtually on Tuesday to try to chart a course for the work. The outbreak is believed to have begun in early January, but the confirmation that the Marburg virus was responsible for the growing cluster of people sick with hemorrhagic-fever-like illness was only confirmed on Monday.

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The post-COVID outlook for decentralized clinical trials

PharmaVoice

The COVID-19 pandemic had many pharmas turning to DCTs as a way to keep the clinical wheel turning. Can the industry keep that flexibility going forward?

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NAC for Thyroid Antibody Reduction, Detoxification and Gut Health

The Thyroid Pharmacist

A few years ago, I was asked: “If the supplement police came to your house and said you had to give up all but one of your supplements, which supplement would you keep, and why?” My answer: N-Acetyl Cysteine (also known as NAC for short), because it has numerous benefits on multiple body systems! Research has shown that NAC helps to reduce thyroid antibodies.

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I. AM. THE. DOCTOR. – Story From The Front Lines

Med Ed 101

This article was originally written by Christine Meyer, MD and I found this story too good not to share. I’m appreciative to her for letting me share it. Deprescribing and dose reductions require all hands on deck. Kudos to all of you pharmacists out there doing your best to ensure patients are taking necessary medication […] The post I.

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Opinion: Improving patient safety shouldn’t be a financial calculation

STAT

A recent study of medical error published in The New England Journal of Medicine reached a shocking conclusion about patient safety: Nearly a quarter century after a highly publicized Institute of Medicine report on the prevalence of patient harm sparked vows to cut the rate by half in five years , “in-hospital adverse events” remain so common that they affect roughly one in four patients.

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Woman of the Week: Bristol Myers Squibb’s Ester Banque

PharmaVoice

The 30-year veteran is heading up the “transformation” of one of the Big Pharma’s most important therapeutic portfolios: hematology.

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Innovation in biosimilars: Leading companies in neuro-degenerative receptor binding drug compositions

Pharmaceutical Technology

The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Biosimilars in Pharmaceuticals: Neuro-degenerative re

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Bridging the Health Equity Gap in Clinical Development

PharmExec

The COVID-19 pandemic has exposed global health inequities and is driving life sciences companies to establish strategies and better leverage data to address systemic causes and improve equity in access to healthcare innovations, particularly in clinical trials.

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STAT+: FDA approves first treatment for leading cause of blindness in older people

STAT

The Food and Drug Administration approved on Friday the first treatment for geographic atrophy, a progressive eye disease and a leading cause of blindness in older people. The new drug, called Syfovre, is made by Apellis Pharmaceuticals.

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Nectin’s Keytruda combo could fill gaps in immuno-oncology’s treatment paradigm

PharmaVoice

The Israeli biotech just entered into a collaboration with Merck to develop its own checkpoint inhibitor alongside the bestselling cancer treatment.

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Innovation in immuno-oncology: Leading companies in gene therapy delivery using viral vectors

Pharmaceutical Technology

The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Immuno-oncology in Pharmaceuticals: Gene therapy deli

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Top 5 Heart Failure Clinical Trials of All Time

Med Ed 101

Heart failure is a disease state that requires a significant number of medications. Guideline-based standards of care now include numerous medications. How did we get there? I outline my top 5 heart failure clinical trials of all time. Feel free to leave a comment if you have a different top 5 or if you feel […] The post Top 5 Heart Failure Clinical Trials of All Time appeared first on Med Ed 101.

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How a Black veteran desegregated a Texas medical school

STAT

When we think of notable civil rights issues in medicine, the best-known cases might be Henrietta Lacks , whose cells were taken without consent for research, or the participants of the Tuskegee Syphilis Study who were subject to unethical experiments. These are important events that changed the course of medicine, but they’re also examples in which Black people were unknowingly harmed as patients.

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For Complement’s CEO, storytelling could be just as critical as data

PharmaVoice

Dr. Rafiq Hasan has his sights on bringing lessons learned at Bayer to ophthalmology-focused Complement Therapeutics.

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Black History Month: Celebrating Influential African American Pharmacists & Industry Trailblazers

Digital Pharmacist

To celebrate Black History Month, join us in honoring notable and courageous African American pharmacists and industry trailblazers. These influential leaders broke societal barriers through the years and paved the way for future generations of African American pharmacists and pharmacy owners. James McCune Smith ( 1813-1865) James McCune Smith was born into slavery in Manhattan until the Emancipation Act of New York set him free at the age of 14.

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Leading innovators in kidney disorder treatment compositions for the pharmaceutical industry

Pharmaceutical Technology

The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: Kidney disorder treatm

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Survey: Nearly 3 in 5 teen girls felt persistently sad or hopeless in 2021

STAT

Teen girls reported record levels of violence, sadness, and thoughts of suicide in 2021, experiencing distress at twice the rate of teen boys, according to new federal data released Monday. The nearly 3 in 5 teen girls who felt persistently sad or hopeless in 2021 was a 60% increase compared to a decade earlier.

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Despite rare disease market growth, pharma leaders see development obstacles ahead

PharmaVoice

Investment in rare disease research is increasing, but a new poll of PharmaVoice readers found that roadblocks remain.

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Small Pharma begins phase 1 mental health therapy trial

Pharma Times

First subject dosed with company’s SPL028 – a proprietary deuterated DMT candidate

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MD Anderson and Xilis partner to expedite new cancer therapies development

Pharmaceutical Technology

The University of Texas MD Anderson Cancer Center has entered a strategic collaboration with biotech company Xilis for advancing new technology and expediting new cancer therapy development. The preclinical research deal will combine the MicroOrganoSphere (MOS) platform of Xilis with the expertise of MD Anderson for advancing new therapies development and cancer research.