Sat.Nov 28, 2020 - Fri.Dec 04, 2020

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A history of Pfizer

pharmaphorum

Few companies embody the term ‘pharma giant’ as much as Pfizer. Here we take a look at the colourful history of one of the biggest drugmakers in the world. Pfizer was founded in 1849 by two recent German immigrants to the USA, Charles Pfizer and Charles Erhart. Both in their mid-twenties, the two men set up what was initially a fine chemicals business in a Brooklyn factory, using a loan from Pfizer’s father as capital.

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Colchicine added to UK’s COVID-19 ‘RECOVERY’ trial

Pharma Times

Commonly used anti-inflammatory drug added to list of potential treatments

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London A.I. Lab Claims Breakthrough That Could Accelerate Drug Discovery

NY Times

Researchers at DeepMind say they have solved “the protein folding problem,” a task that has bedeviled scientists for more than 50 years.

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COVID-19 collaboration to study patient risk via blood

Outsourcing Pharma

Health tech specialists GoodCell are working with the New York Blood Center to identify COVID-19 patients with elevated risk of adverse clinical outcomes.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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iRhythm digital heart monitoring service backed by NICE

pharmaphorum

A heart monitor developed by iRhythm has become the first product to be endorsed by NICE in a pilot project covering digital health technologies. In new guidance, the health technology assessment (HTA) agency has recommended iRhythm’s Zio XT service for detecting abnormal heart rhythms – provided NHS organisations that deploy it collect evidence of its benefits.

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PureTech launches phase II ‘long COVID’ drug trial

Pharma Times

LYT-100 will be evaluated in patients with persistent symptoms caused by COVID-19

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More Trending

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COVID-19 Vaccinations – Where a Commitment to Diversity is Essential

Eye on FDA

In my last posting on preparedness for a post-vaccination world I touched on some of the questions facing employers in general – policy questions that should be considered now for the eventualities of later. But digging a little deeper, there are also questions to consider with respect to support for ensuring access to vaccines by communities of color.

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Valneva accelerates Lyme disease vaccine R&D project with Pfizer

pharmaphorum

Valneva has said it plans to accelerate research into its Lyme disease vaccine candidate VLA15, bringing forward a trial including children into the first quarter of 2021. Subject to approval from regulators the vaccine specialist said it plans the trial known as VLA15-221 as a randomised, observer-blind phase 2 study including around 600 healthy people aged 5-65 years of age.

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UK approves Pfizer/BioNTech’s COVID-19 vaccine

Pharma Times

First doses for emergency use will be delivered 'immediately'

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Moderna Applies for Emergency F.D.A. Approval for Its Coronavirus Vaccine

NY Times

The first shots could be given as early as Dec. 21, if authorization is granted.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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COVID-19 fueling decentralized trial surge: Oracle survey

Outsourcing Pharma

A recent survey conducted by Oracle reveals trial professionalsâ thoughts, feelings and behavior around decentralized research in the face of the pandemic.

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Healthware Group buys Finnish digital agency Make Helsinki

pharmaphorum

Healthcare agency, consultancy and digital health group Healthware Group has acquired Finland-based digital service development and creative agency Make Helsinki. The acquisition builds on prior collaborations between the two organisations, including in best-in-class full-service agency offerings, digital transformation, technology/enterprise solutions and corporate venturing.

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Bayer inks deal with Blackford Analysis to develop radiology AI platform

Pharma Times

Agreement will aim to develop a platform to support radiologists' decision-making

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Who Will Get the Coronavirus Vaccine First?

NY Times

A C.D.C. advisory panel will decide on its recommendations on Tuesday afternoon. Here’s what we expect, along with answers to other questions about the new shot.

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Dive into the digital evolution of clinical trials

Outsourcing Pharma

Taking place December 9, the Digital Advances in Clinical Trials webinar covers notable advances in clinical trial technology, and the future of the field.

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Pfizer cut vaccine production targets because of raw material shortage – reports

pharmaphorum

Pfizer slashed its production targets for its COVID-19 vaccine because of a lack of raw materials for its supply chain, according to press reports. The big pharma has said in recent weeks that it expects to produce 50 million doses of the vaccine it developed with the German BioNTech, down from an earlier target of 100 million doses. That’s enough to inoculate 25 million people as the dosing schedule involves two shots three weeks apart.

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COVID-19 could cause long-term lung damage, research finds

Pharma Times

Research conducted at Oxford University used new scanning method

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When and How You’ll Get a Vaccine

NY Times

Multiple inoculations for the coronavirus are making their way through the approval process. Here’s what we know about the plan for their distribution.

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New patent expiration for Teva Branded drug PREVEN EMERGENCY CONTRACEPTIVE KIT

Drug Patent Watch

Annual Drug Patent Expirations for PREVEN+EMERGENCY+CONTRACEPTIVE+KIT Preven Emergency Contraceptive Kit is a drug marketed by Teva Branded Pharm and is included in one NDA. There is one patent protecting this…. The post New patent expiration for Teva Branded drug PREVEN EMERGENCY CONTRACEPTIVE KIT appeared first on DrugPatentWatch - Make Better Decisions.

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‘Knowledge is power’ for rare diseases and NAbs

pharmaphorum

Cure Rare Disease’s Rich Horgan discusses the importance of preclinical NAbs screening and helping rare disease patients better understand their eligibility for gene therapies. Neutralising antibodies (NAbs) present a unique challenge to researchers looking to treat patients with AAV treatment. As AAV is a virus derived from the common cold, the immune system can easily have levels of pre-existing NAbs that will recognise and neutralise AAV, rendering it ineffective.

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Dupixent approved in EU for atopic dermatitis in children

Pharma Times

First biologic to be approved for children aged six to 11 years with condition

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Berry-Flavored H.I.V. Medication Is Ready for Babies

NY Times

For the 80,000 children who die of H.I.V. each year, drugs are often bitter or hard to swallow. Dolutegravir will soon come in a tasty dissolving tablet.

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What Can Supplements Really Do For Health and Beauty?

Pharma Mirror

Taking a health supplement can positively impact your health and beauty if you choose the right one for your needs. According to Mayo Clinic, the benefits of supplements specifically apply to pregnant people (subject to doctor’s recommendation), over the age of 50, who have food allergies or digestive conditions or miss large food groups in their diet.

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The urgent need for education and awareness about mitochondrial disease

pharmaphorum

Delayed diagnosis, misdiagnosis, and no cure or disease modifying treatments – children living with mitochondrial disease face all the issues often associated with rare diseases. It’s a problem that Michelle Bamber, whose two little girls both have the life-limiting condition, knows only too well. Lily was a happy, contented baby, and her parents had no cause for concern until she went for her two-year check and was put on a pathway to diagnosis.

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DSRU plans ‘post-authorisation’ study of COVID-19 vaccines in the UK

Pharma Times

Drug Safety Research Unit set to conduct active surveillance study on COVID-19 vaccines

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Moderna to Begin Testing Its Coronavirus Vaccine in Children

NY Times

The company said the trial would involve children ages 12 through 17.

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The Keto Diet: A Beginner’s Guide on Making the Switch to Keto

Pharma Mirror

The keto diet, also known as a ketogenic diet, is a type of food-based lifestyle that many people adopt. Essential, it lets you eat foods that are very high in fat and low in carbohydrates. The keto diet lowers insulin levels and increases your body’s ability to burn fat. This diet type is very alluring as it keeps you healthy and feeling full, unlike other diets.

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Healthcare that no longer leaves out the patient

pharmaphorum

For so long the US healthcare system was built around the provider, with appointments and services set by the provider (along with insurance reimbursement systems). This structure relies on in-person visits of patients to operate and become profitable. But when the industry suddenly shifted due to COVID-19, so too did the power dynamics of the patient-provider relationship.

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AbbVie partners with Frontier Medicines on protein degrader development

Pharma Times

Partnership will seek to develop small molecules for oncology/immunology targets

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China Poised to Be First to Distribute Virus Vaccine in Latin America, U.S. Official Says

NY Times

China, which has been expanding its presence in the region, is likely to beat the United States in its own backyard with vaccine diplomacy as Washington looks “at taking care of the U.S. first.”.

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New patent for Ucb Inc drug VIMPAT

Drug Patent Watch

Annual Drug Patent Expirations for VIMPAT Vimpat is a drug marketed by Ucb Inc and is included in three NDAs. It is available from three suppliers. There is one patent…. The post New patent for Ucb Inc drug VIMPAT appeared first on DrugPatentWatch - Make Better Decisions.

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Merck KGaA signs DNA damage response cancer deal with Artios Pharma

pharmaphorum

Germany’s Merck KGaA has joined with UK-based Artios Pharma in a potential multi-billion dollar deal to investigate novel DNA damage response targets in cancer. The principle of DNA damage response is already being exploited by AstraZeneca and other companies with their poly (ADP-ribose) polymerase (PARP) inhibitor drugs. These target the inherent genetic instability in certain cancer cells, which have switched to a backup mechanism to repair damage to their DNA code.

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Researchers warn pandemic could delay cancer advances ‘by almost a year’

Pharma Times

Survey included input from scientists at The Institute of Cancer Research, London

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New Guidelines Cover Opioid Use After Children’s Surgery

NY Times

Parents should not be afraid of managing the child’s pain with opioids when they are needed, but should make sure a child does not have access to leftover doses.

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New patent for Bausch drug JUBLIA

Drug Patent Watch

Annual Drug Patent Expirations for JUBLIA Jublia is a drug marketed by Bausch and is included in one NDA. It is available from one supplier. There are twelve patents protecting…. The post New patent for Bausch drug JUBLIA appeared first on DrugPatentWatch - Make Better Decisions.

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