Phenobarbital as First-Line Medication for Alcohol Withdrawal: Have You Switched From Benzodiazepines Yet?
ALiEM - Pharm Pearls
JUNE 1, 2023
“Dose adjustment” is recommended by the manufacturer in hepatic dysfunction, but no value is provided [10]. Clinical pearl: Hepatic encephalopathy is a strong contraindication to phenobarbital [9, 10]. Clinical pearl: Hepatic encephalopathy is a strong contraindication to phenobarbital [9, 10]. barbiturates or benzodiazepines).
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