STAT

APRIL 6, 2023

The initial clinical trials have yielded progress against brain tumors and new, potentially fatal, risks. The success of CAR-T immunotherapies against blood cancers has raised hope that CAR-T can bring breakthroughs to brain cancers, which haven’t had new treatments for decades.

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STAT

JUNE 28, 2023

But the trauma that patients experience as they deal with the disease can pose a lifelong risk to their mental health, according to a recent analysis published in JAMA Pediatrics. The meta-analysis of 52 clinical studies measured the prevalence and severity of psychological disorders in over 20,000 young cancer survivors.

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STAT

NOVEMBER 22, 2022

With the official start of winter still weeks away, pediatric hospitals are facing crushing caseloads of children sick with RSV and other viral illnesses. A storm of these proportions should demand not only crisis clinical measures, but also community prevention efforts. is abandoning them. Read the rest…

Hospitals 364

Hospitals 364

ALiEM - Pharm Pearls

FEBRUARY 26, 2024

Clinical and therapeutic approach to childhood acne: an update. Pediatr Dermatol. Copyright Images and cases from the Society of Academic Emergency Medicine (SAEM) Clinical Images Exhibit at the 2023 SAEM Annual Meeting | Copyrighted by SAEM 2023 – all rights reserved. 2009 Jul-Aug;26(4):373-80. doi: 10.1111/j.1525-1470.2009.00932.x.

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ALiEM - Pharm Pearls

OCTOBER 2, 2023

A 6-year-old male presented to the pediatric emergency department (PED) for scalp lesions. Pediatr Emerg Care. Copyright Images and cases from the Society of Academic Emergency Medicine (SAEM) Clinical Images Exhibit at the 2023 SAEM Annual Meeting | Copyrighted by SAEM 2023 – all rights reserved. 2014 Jun;30(6):437-9.

Medical Schools 186

Medical Schools 186

Outsourcing Pharma

NOVEMBER 17, 2023

OSP was delighted to speak to Galina Nesterova, executive medical director at the Rare Disease & Pediatrics Center of Excellence, and Susan McCune, vice president of pediatrics and clinical pharmacology both within medical science and strategy at PPD, part of Thermo Fisher.

Clinical Pharmacology 97

Clinical Pharmacology 97

ALiEM - Pharm Pearls

NOVEMBER 15, 2023

7] Diagnosis is based largely upon the history and clinical presentation. Cyanide levels can be obtained for confirmation but do not generally return in a clinically relevant time frame. Dosing for 3% sodium nitrite solution [8]: Adults: 300 mg (10 mL) no faster than 5 mL/min Pediatrics: 6 mg/kg (0.2 Pediatrics.

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STAT

NOVEMBER 30, 2022

But once they walk out of the clinic, the same condition could impact each of their lives in considerably different ways.

Hospitals 246

Hospitals 246

ALiEM - Pharm Pearls

MARCH 27, 2023

An 8-year-old Caucasian male with no significant past medical history presented to the pediatric emergency department (ED) with complaints of three days of abdominal pain and dysuria, accompanied by nausea, vomiting, and poor oral intake. Glob Pediatr Health. View other cases from this Clinical Image Series on ALiEM.

Medical Schools 130

Medical Schools Hospitals 130

STAT

JUNE 28, 2023

A young girl, maybe 5 or 6 years old, had come into Yoram Unguru’s clinic with acute lymphoblastic leukemia, the most common of all childhood cancers. One of the drugs needed for treatment was methotrexate. The only problem was that the drug was in short supply.

Chemotherapy 267

Chemotherapy Hospitals Drug Pricing 267

ALiEM - Pharm Pearls

FEBRUARY 27, 2023

A 15-year-old male presents to the pediatric Emergency Department (ED) for evaluation of neck pain for three weeks. There are no published case reports of traumatic, pediatric AO joint septic arthritis. View other cases from this Clinical Image Series on ALiEM. This patient developed septic arthritis following trauma.

Diabetes 158

Diabetes 158

World Pharma News

APRIL 12, 2024

The results of the clinical study were published today in Nature Medicine. This combined approach, developed by Florida International University cancer researcher Diana Azzam, was used successfully for the first time to guide treatment of relapsed pediatric cancer patients in collaboration with First Ascent Biomedical and Dr.

Hospitals 82

Hospitals 82

Pharmaceutical Technology

MARCH 22, 2024

Lisata Therapeutics announced a rare pediatric drug designation for LSTA1, which is being studied in several early to mid-stage clinical studies.

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ALiEM - Pharm Pearls

NOVEMBER 1, 2023

What clinical presentation and medication is associated with this urinary discoloration? 6-9] Entacapone Hydroxocobalamin Levodopa Phenazopyridine Rifampin Senna Sulfasalazine Clinical Pearls Deferoxamine binds with free iron and is excreted as ferrioxamine in urine, causing a rusty discoloration known as vin rosé urine. Deferoxamine.

Clinical Pharmacology 158

Clinical Pharmacology Dosage Compounding 158

STAT

MARCH 28, 2023

At our pediatric clinic, we recently saw a child whose mother lost her job during the pandemic working as a caterer. The mother struggled to put food on the table after the precipitous loss of income. After the family enrolled in SNAP, we could literally measure how that policy benefited our young patient.

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Express Pharma

MARCH 4, 2024

Attention-deficit/hyperactivity disorder (ADHD) is a clinically heterogenous neurodevelopmental disorder with high rates of comorbidity with other childhood-onset psychiatric disorders as well as learning disorders. per cent for pediatric and adult ADHD patients, respectively. per cent in the pediatric population and 17.5

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Pharmacy Times

AUGUST 4, 2022

Electronic symptom self-measuring provided early detection of toxic effects and helped anticipate necessary medical interventions for pediatric patients with cancer.

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Pharmaceutical Technology

FEBRUARY 8, 2024

NiKogene is under clinical development by Kian Immune Cell and currently in Phase I for Pediatric Diffuse Intrinsic Pontine Glioma.

Immunity 40

Immunity Immunization 40

Outsourcing Pharma

JULY 18, 2022

A pediatric clinical trial expert from the CRO discusses the unique challenges involved in designing a study when the patients involved are little ones.

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Board Vitals - Pharmacist

OCTOBER 1, 2022

Pediatricians and Pediatric Nurse Practitioners specialize in caring for children from infancy throughout adolescence. In this article we’ll take a look at some of the key similarities and differences between pediatricians and pediatric nurse practitioners. What is the role of a Pediatric Nurse Practitioner?

Medical Schools 52

Medical Schools Hospitals 52

Board Vitals - Pharmacist

OCTOBER 1, 2022

Pediatricians and Pediatric Nurse Practitioners specialize in caring for children from infancy throughout adolescence. In this article we’ll take a look at some of the key similarities and differences between pediatricians and pediatric nurse practitioners. . What is the role of a Pediatric Nurse Practitioner?

Medical Schools 52

Medical Schools Hospitals 52

Board Vitals - Pharmacist

AUGUST 9, 2022

See where you stand and try your hand at these 5 free Certified Pediatric Nurse Exam practice questions from the all-new BoardVitals Certified Pediatric Nurse Exam Question Bank. . . The Certified Pediatric Nurse Exam is taken by pediatric nurses looking to go beyond their basic RN licensures. How did you do?

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Pharmaceutical Technology

SEPTEMBER 22, 2022

Avrobio has received rare pediatric disease designation from the US Food and Drug Administration (FDA) for its investigational gene therapy, AVR-RD-04, designed to treat cystinosis. The FDA's rare pediatric disease designation and Voucher Program aid the development of new drugs and biologics to prevent and treat rare paediatric ailments.

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Pharmacy Times

MAY 31, 2023

Pediatric drug development, which has a complex background and history, has fundamental catches based around how children are defined in the context of clinical studies.

Drug Development 49

Drug Development 49

Pharmacy Times

JUNE 16, 2023

Imposing the FDA on-label/off-label framework on administratively defined "children" resulted in a regulatory demand for pediatric studies that had no basis in clinical medicine, with the exception of the small group of preterm newborns.

Labelling 52

Labelling 52

LifeProNow

MARCH 13, 2023

last year as the first and only therapy to delay the onset of Stage 3 type 1 diabetes (T1D) in adults and pediatric patients aged 8 years and older with Stage 2 T1D. TZIELD is also in late-stage clinical development for the treatment of pediatric and adolescent patients that are newly diagnosed with clinical T1D (Stage 3).

Diabetes 130

Diabetes Immunity Immunization 130

Board Vitals - Pharmacist

JANUARY 11, 2024

Here are some of their stories: Forty-eight years ago, in 1976, a pediatric patient was admitted to Hammersmith Hospital, London. Pharmaceutical industry: Pharmacists may design or conduct clinical drug trials and help to develop new drugs. Or recognize them on social media by using #NationalPharmacistDay. Studying for the NAPLEX ?

Retail Drug Stores 98

Retail Drug Stores Hospitals Doctor of Pharmacy Dosage 98

Pharmaceutical Business Review

MAY 10, 2024

The company plans to allocate these Series C funds primarily towards concluding the clinical trials for obtaining regulatory approval of its leading candidate, ARD-101, aimed at treating hyperphagia in Prader-Willi Syndrome (PWS) patients. This capital influx comes after Aardvark secured $29m in a Series B funding round in August 2021.

Compounding 52

Compounding 52

Outsourcing Pharma

SEPTEMBER 22, 2020

The CRO will work with the Leukemia and Lymphoma Society on a global master clinical trial to explore treatments for pediatric acute leukemia.

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European Pharmaceutical Review

MARCH 4, 2024

Importance of the new data for the Novartis gene therapy This data is “the first Zolgensma open-label clinical study to include older and heavier, as well as previously treated patients,” according to Dr Sandra Reyna, Chief Scientific Advisor and Head of Global Medical Engagement for SMA at Novartis.

Labelling 82

Labelling 82

Pharmaceutical Technology

MAY 17, 2023

TAK-755 is the first and only treatment in clinical development that provides targeted replacement of ADAMTS13, addressing the underlying cause of the disease. “We The Phase III trial assessed TAK-755’s clinical benefit across several clinically relevant endpoints, against plasma-based therapies, in a randomised cross-over study.

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Pharmaceutical Technology

JANUARY 17, 2023

Orphagen Pharmaceuticals has received a rare pediatric disease designation (RPDD) for OR-449 from the US Food and Drug Administration (FDA) to treat paediatric adrenocortical carcinoma (ACC). The post Orphagen’s ACC therapy receives FDA rare pediatric disease status appeared first on Pharmaceutical Technology.

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Pharmaceutical Technology

JUNE 5, 2023

Kid EDV is under clinical development by ImmunityBio and currently in Phase I for Pediatric Diffuse Intrinsic Pontine Glioma. According to GlobalData, Phase I drugs for Pediatric Diffuse Intrinsic Pontine Glioma does not have sufficient historical data to build an indication benchmark PTSR for Phase I.

Immunity 52

Immunity Immunization Vaccines Drug Development 52

Pharma Mirror

FEBRUARY 4, 2022

The team, led by the Pediatric Trials Network at Duke University, also includes the Gabriella Miller Kids First Data Resource Center (DRC) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). POP02 is one of several cohort studies within the.

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pharmaphorum

NOVEMBER 11, 2022

Leading with practical insights from the best in the industry, the 4th Annual Inflammasome Therapeutics Summit is returning in person on November 29 – December 1 to Boston to equip you with the knowledge and connections to propel the next frontier of inflammasome therapeutics from pipeline to clinical and commercial reality.

Medical Schools 52

Medical Schools Immunity Immunization Hospitals 52

European Pharmaceutical Review

APRIL 3, 2023

These results have led to a major amendment in a European Phase III paediatric clinical trial. The oncology treatment showed clinical activity across patients of all ages with the three neuroblastoma-specific hotspot ALK mutations. The data showed 63 percent of patients responded to the combined treatment.

Chemotherapy 79

Chemotherapy Hospitals 79

ID Stewardship

MAY 21, 2023

Infectious diseases conferences may have emphasis on things such as antimicrobial stewardship, infection prevention and control, clinical microbiology, immunocompromised hosts, pediatrics, fungal pathogens, microbial breakpoints or other. Every conference offers unique opportunities for learning. Jude/PIDS St.

Chemotherapy 52

Chemotherapy 52