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L and J-HZ by L&J Bio for Herpes Zoster (Shingles): Likelihood of Approval

Pharmaceutical Technology

L and J-HZ is under clinical development by L&J Bio and currently in Phase I for Herpes Zoster (Shingles).

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VTP-400 by Barinthus Biotherapeutics for Herpes Zoster (Shingles): Likelihood of Approval

Pharmaceutical Technology

VTP-400 is under clinical development by Barinthus Biotherapeutics and currently in Phase I for Herpes Zoster (Shingles).

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Shingles vaccine offers a decade of protection in older adults

European Pharmaceutical Review

GSK announced Shingrix (Zoster Vaccine Recombinant, Adjuvanted), the first approved shingles vaccine to combine a non-live antigen with a GSK-made adjuvant, can prevent shingles (herpes zoster) for at least decade. Shingles occurs when the varicella zoster virus (VZV) is reactivated in a patient.

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Japan’s MHLW accepts GSK’s submission for shingles vaccine in adults

Pharmaceutical Technology

The Japanese Ministry of Health, Labour and Welfare (MHLW) has accepted GlaxoSmithKline’s (GSK) regulatory application for recombinant, adjuvanted Zoster vaccine, Shingrix, for preventing shingles (herpes zoster) in at-risk adults of the age 18 years and above.

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Look out GSK, Pfizer and BioNTech are coming for Shingrix

pharmaphorum

Having already brought their mRNA-based CVID-19 vaccine Comirnaty to market at breakneck speed, Pfizer and BioNTech are hoping to fast-track a vaccine for shingles based on the same technology platform through clinical development, with trials due to start later this year.

Vaccines 104
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China’s CanSino seeks more vaccine contracts after AstraZenca deal

Express Pharma

The company has paused its clinical trials for mRNA COVID vaccine candidates, and will explore using the technology for other diseases. It is now developing an inhalable vaccine against the zoster virus, as the inhalable COVID vaccine stimulated strong mucosal immunisation and a robust immune response, Yu said. million yuan ($106.5

Vaccines 114
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GSK wants to double Shingrix sales, and a new FDA okay could help

pharmaphorum

The FDA review was based mainly on a clinical trial showing that Shingrix was able to protect younger patients undergoing a bone marrow transplant for haematological cancers from developing shingles, but also included data from people immune-suppressed due to HIV, solid tumour and renal transplants.