article thumbnail

Off-label Use

RX Note

In fact, off-label drug uses can become widely entrenched in clinical practice and become predominant treatments for a given clinical condition. In a study published in JAMA Internal Medicine , off-label use lacking strong scientific evidence had a higher adverse drug event rate compared with on-label use.

article thumbnail

Developing a new treatment paradigm for chronic kidney disease

European Pharmaceutical Review

This month, new data from Novo Nordisk has revealed that semaglutide could become the first GLP-1 treatment option for patients with type 2 diabetes and chronic kidney disease (CKD). This leads to the formation of immune complexes that deposit in the glomerulus and result in haematuria, proteinuria, and decline in kidney function.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Developing a new treatment paradigm for IgAN

European Pharmaceutical Review

This month, new data from Novo Nordisk has revealed that semaglutide could become the first GLP-1 treatment option for patients with type 2 diabetes and chronic kidney disease (CKD). This leads to the formation of immune complexes that deposit in the glomerulus and result in haematuria, proteinuria, and decline in kidney function.

article thumbnail

Is Stevia Good or Bad for Hashimoto’s Disease?

The Thyroid Pharmacist

I knew he was right — sugar can contribute to a yeast overgrowth, lowered immunity, blood sugar issues, weight gain, diabetes, and a whole host of health problems (1-3) — but I was a sugar addict, and it was devastating to think that I would have to let go of this old friend and not have any sweetness in my life.

article thumbnail

Top 9 Takeaways From 2232 People With Hashimoto’s

The Thyroid Pharmacist

Vitamin D supports the immune system by enhancing the pathogen-fighting effects of white blood cells, which are important parts of immune defense. When it leaks into the bloodstream, the body does not recognize it, and labels the structure as a foreign invader and attacks it. It’s also great for boosting our immunity!

Immunity 110
article thumbnail

The Ultimate Guide To Using Enzymes with Hashimoto’s

The Thyroid Pharmacist

Her body was making numerous inflammatory immune complexes to EVERY protein she was eating! She also began using systemic enzymes (enzymes that are taken away from food and break down inflammatory immune complexes), and started noticing that her eyes and face were less swollen — within a few weeks. Systemic Enzymes.

article thumbnail

Moving towards oral delivery of biologics

European Pharmaceutical Review

1 Used to treat a range of chronic diseases (eg, diabetes, rheumatoid arthritis, psoriasis, Crohn’s disease, haemophilia, etc), it is projected that the sales of biologics will rise from $380 billion in 2022 to $416 billion in 2023, and to almost $600 billion in 2027. Diabetes Therapy. The Business Research Company. 2019;10(2):437–49.