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STAT+: In small study, weight loss drug boosts immune cells that help fight cancer

STAT

Prior research has shown that people with obesity have deficiencies in their “natural killer” cells, or NK cells — immune cells that help in combating cancer.

Immunity 251
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Sanofi to acquire Provention Bio, adding to portfolio TZIELD for type diabetes (T1D)

LifeProNow

-based, publicly traded biopharmaceutical company focused on intercepting and preventing immune-mediated diseases including type 1 diabetes (T1D), have entered into an agreement under which Sanofi has agreed to acquire Provention Bio, Inc., for $25.00 per share in cash, representing an equity value of approximately $2.9

Diabetes 130
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Common drug could facilitate “huge step-change” in managing type 1 diabetes

European Pharmaceutical Review

Results from a world-first human trial, published in the New England Journal of Medicine , has shown that a drug called baricitinib has promise as the first disease-modifying treatment of its kind for type 1 diabetes, that can be administered as a tablet. 

Diabetes 105
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Vertex pays CRISPR to use its gene editing tech for diabetes drugs

BioPharma Dive

Vertex will license CRISPR technology to develop insulin-producing islet cells that are more resistant to immune rejection, adding to other efforts directed at Type 1 diabetes.

Diabetes 112
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STAT+: Pharmalittle: New medication appears to stave off type 1 diabetes; CRISPR pioneer founds another startup

STAT

Here’s the latest, and do keep in touch … A new medication appears to be helping stave off the development of type 1 diabetes , Nature writes. Approved last November in the United States, it’s also the first drug proven to delay the onset of an autoimmune disorder.

Diabetes 196
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FDA approves first drug to delay type 1 diabetes

European Pharmaceutical Review

Tzield (teplizumab-mzwv), the first drug to help prolong the onset of stage 3 type 1 diabetes in adults and children over eight years old with stage 2 type 1 diabetes, has been approved by the US Food and Drug Administration (FDA). The drug binds to certain immune system cells and delays progression to stage 3 type 1 diabetes.

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Lonza and Vertex to partner to manufacture diabetes cell therapies

European Pharmaceutical Review

Lonza and Vertex Pharmaceuticals Incorporated have agreed to collaborate to support the manufacture of Vertex’s Type 1 diabetes cell therapy portfolio. It is delivered by an infusion into the hepatic portal vein and requires chronic immunosuppressive therapy to protect the islet cells from immune rejection.