Fri.Jan 26, 2024

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Opinion: Congress must pass the child tax credit deal to support kids’ health

STAT

When I enter, “what is pediatrics?” into an image search engine, I get back dozens of stock photos with smiling physicians listening to beaming children’s hearts or looking in their ears. I love those images. They reflect the routine joy and trust that encompass many days in the life of a pediatrician. Increasingly, though, the answer to that question doesn’t quite match the happy imagery.

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SAEM Clinical Images Series: A Rare Case of Purpura

ALiEM - Pharm Pearls

An 88-year-old female presented to the ER with a chief complaint of cough, vague abdominal pain, and a rash. The patient stated that she was started on Cipro eyedrops 1 or 2 days prior to presentation for a possible eye infection. A day prior to presentation she developed a purple purpuric rash on her lower extremities that gradually progressed up her legs, and was present on her buttocks thighs, and lower legs.

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Trending Sources

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A call to add sexual orientation and gender identity data to electronic health records

STAT

There are more openly LGBTQ+ people in the U.S. than ever, but little is known about the unique health challenges they may face. That’s why some researchers are urging health systems to build the acronym SOGIE — for patients’ sexual orientation and gender identity and expression — into their data collection. In a paper published Wednesday in JAMA Cardiology , a group of cardiologists write that there is an urgent need to begin collecting SOGIE data more systematically

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‘1 plus 1 equals 3’ — the co-CEO model in pharma

PharmaVoice

Amylyx Pharmaceuticals’ co-founders and co-CEOs Josh Cohen and Justin Klee explain their approach to dual leadership and why it can be a good fit in life sciences.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Merck, Johnson & Johnson CEOs agree to testify in Congress on high drug prices, avoiding Bernie Sanders’ subpoena

STAT

WASHINGTON — Merck CEO Robert Davis and Johnson & Johnson CEO Joaquin Duato have agreed to voluntarily testify before the Senate health committee, avoiding a threatened subpoena, the committee announced Friday. The decision by the executives came after a public pressure campaign by Sanders to get the two executives and Bristol Myers Squibb CEO Chris Boerner to testify about why prices for their drugs are higher in the United States than in other countries.

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Adverse Event Reports Linked to Counterfeit Ozempic on the Rise

Pharmaceutical Commerce

Concerns regarding hypoglycemia potentially linked to a counterfeit version of Ozempic come at a time in which reports have grown regarding the improper use of GLP-1 receptor agonists for the purpose of cosmetic weight loss.

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EMA recommends earlier use of Bristol Myers cell therapy for multiple myeloma

BioPharma Dive

The opinion would allow Abecma to be prescribed after two standard therapies and is the latest sign of CAR-T’s growing use in earlier cancer treatment.

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Eli Lilly overtakes Tesla in market value

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hello, everyone. Damian here with a look at a biotech rarity, a milestone on Wall Street, and pharma’s latest run-in with Washington.

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Pharmacy First success relies on pharmacy and general practice ‘relationships’

The Pharmacist

The ‘success and full benefit’ of Pharmacy First will be reliant on the ‘building and sustaining of local relationships’ between general practice and community pharmacy teams, NHS England (NHSE) has said as the service is confirmed to launch next week. In a letter to primary care stakeholders published yesterday, NHSE said that Pharmacy First would […] The post Pharmacy First success relies on pharmacy and general practice ‘relationships’ appeared first on The Pharmacist.

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STAT+: Up and down the ladder: The latest comings and goings

STAT

Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others.  That’s right. Send us your changes, and we’ll find a home for them.  Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Does Patient Priorities Care Result in Better Outcomes for Patients?

Pharmaceutical Commerce

A non-randomized control trial investigates whether older adults with multiple chronic conditions can benefit by receiving more specialized services.

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STAT+: Pharmalittle: We’re reading about Sanders jabbing Merck’s CEO, fixing drug shortages, and more

STAT

And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is still shaping up. We do, however, plan to catch up on our reading, promenade with the official mascots, and hold another listening party with Mrs. Pharmalot. For now, the rotation will likely include this , this , this and this.

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BHF data reveals early heart disease deaths rise to highest level

Pharma Times

In 2022, over 39,000 people in England died prematurely of cardiovascular conditions

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CAR-T therapies and cancer risk: No easy answers for the FDA

Pharmaceutical Technology

CAR-T cell therapies can provide durable cancer remission, however, a recent FDA investigation into reports of secondary T-cell malignancies has increased scrutiny of their risk profiles.

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AbbVie invests $223m in Singapore biologics site

pharmaphorum

AbbVie has broken ground on a new $223 million expansion of its biologics manufacturing facility in Singapore, creating around 100 new jobs

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Eosinophilic esophagitis medicine approval expanded

European Pharmaceutical Review

The US Food and Drug Administration (FDA) has approved Dupixent ® (dupilumab) as a treatment for children patients aged one to 11 years, weighing at least 15kg with eosinophilic esophagitis (EoE). This new authorisation by the FDA’s expands its initial approval for EoE in May 2022 for patients aged 12 years and older, weighing at least 40kg. “With this approval, Dupixent becomes the first and only treatment option for EoE patients aged one year and older, weighing at least 15kg” “With this

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Britain will be first to get new Mounjaro device, says Lilly

pharmaphorum

Eli Lilly is weeks away from launching Mounjaro in the UK, after getting approval from the MHRA for a multi-dose injector version for diabetes and obesity

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Key vaccine adjuvant biosynthesised

European Pharmaceutical Review

A paper, published in Nature Chemical Biology has reported the first ‘free-from ‘tree’ production of a key vaccine ingredient sourced from the soapbark tree. Researchers from the John Innes Centre, a research institute in the UK, have reconstituted the chemical pathway of the potent adjuvant molecule QS-21 in a tobacco plant. Bioengineering vaccine adjuvants The paper explained: “QS-21 is a potent vaccine adjuvant currently sourced by extraction from the Chilean soapbark tree.

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NHS urges more young people to take up HPV vaccine

Pharma Times

HPV is a common group of viruses which can sometimes lead to cancer

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New NHS trust should oversee, sell patient data, says report

pharmaphorum

Report on UK biotech sector by Tony Blair and William Hague calls for an NHS trust to be set up to oversee and sell patient data

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Doctors like me get the blame when hospitals run out of medicines. Politicians get off scot-free | Ammad Butt

The Guardian - Pharmaceutical Industry

Frontline staff are having to make compromises to treat patients appropriately. It’s scandalous nothing is being done Medicine shortages in the UK have been a regular feature on newspaper front pages in recent years. As a doctor on the frontline, I see how this instability in our medicine supply chain is playing out on the ground. I work in a large city hospital and am used to meeting disgruntled patients who have had to wait hours in clinic to receive treatment.

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Then there were two: ArriVent set to list after $175m IPO

pharmaphorum

ArriVent BioPharma completes the second biotech IPO of 2024, raising $175m that will help advance its late-stage lung cancer drug furmonertinib

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'Cancer-cooling' protein puts bowel cancer on ice

World Pharma News

A protein in the immune system can be manipulated to help overcome bowel cancer, according to new research from The Australian National University (ANU). Bowel cancer claims more than 100 lives in Australia each week, yet around 90 per cent of cases can be successfully treated if detected early.

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Celltrion Launches 80 mg YUFLYMA (adalimumab-aaty) in the U.S.

Big Molecule Watch

On January 17, 2024, Celltrion announced the U.S. launch of a new, 80 mg/0.8 ml dosage strength of its HUMIRA® biosimilar, YUFLYMA® (adalimumab-aaty). As we previously reported , Celltrion received FDA approval for an 80 mg/0.8 ml dose and a 20 mg/0.2 ml dose on October 4, 2023. Celltrion’s January 2024 announcement indicates that it expects the 20 mg version of YUFLYMA® “to be available in pharmacies in late Q1 2024.

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AbbVie invests $223m in Singapore manufacturing site

Pharmafile

AbbVie has announced that it has invested $223m in an expansion to its Singapore manufacturing facility. This will create more than 100 new jobs and increase the company’s biologics manufacturing capacity. The facility is located in Singapore’s Tuas Biomedical Park and is a state-of-the-art small-molecule and biologics manufacturing site. The investment is intended to add […] The post AbbVie invests $223m in Singapore manufacturing site appeared first on Pharmafile.

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PTC Duchenne drug approval set to be revoked in Europe

BioPharma Dive

The EMA’s drugs committee again recommended rescinding an OK for Translarna, which was cleared in 2014 despite questions about its benefit.

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MHRA approves Mounjaro for diabetes and weight management

Pharmafile

The Medicines and Healthcare products Regulatory Agency (MHRA) has announced that it has approved a four-dose version of the diabetes and weight management medicine Mounjara (tirzepatide) in the form of Mounjaro KwikPen. The four-dose version is intended to cover a month’s treatment and is approved to treat adult patients with type 2 diabetes and for […] The post MHRA approves Mounjaro for diabetes and weight management appeared first on Pharmafile.

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From pandemic spotlight to global progress: Navigating technology transfer for healthcare innovation

pharmaphorum

From pandemic spotlight to global progress: Navigating technology transfer for healthcare innovation Mike.

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Atossa Therapeutics progresses Phase II preventative breast cancer therapy

Pharmaceutical Technology

Atossa Therapeutics estimates a Q3 Phase II readout for Z-endoxifen, as it plans a Phase III preventative breast cancer trial.

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JP Morgan 2024 – Frank Gleeson

pharmaphorum

JP Morgan 2024 – Frank Gleeson Mike.

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Revitalize Your Pharmacy’s Front-End: Strategies for a Positive Customer Experience

Digital Pharmacist

In the fast-paced world of community pharmacy, providing an inviting and efficient front-end experience is crucial for customer satisfaction. A well-designed and refreshed pharmacy front end not only enhances the customer experience but also contributes to the overall success of your business. In this blog post, we will explore effective ways to refresh your pharmacy’s front end and create a positive environment for both customers and staff.

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Breaking the Chains of Opioid Addiction: The Promise of Long-Acting Injectables

Pharmaceutical Commerce

As providers and healthcare professionals recognize the potential of long-acting injectables to fight the opioid epidemic, many are actively transitioning from oral options to injectables.

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Recent Licensing Agreement Poised to Advance Company ADC

PharmExec

In an interview with PharmExec Associate Editor Don Tracy, Jingsong Wang discusses Nona Biosciences’ recent exclusive license agreement with Pfizer Inc. for the development and commercialization of HBM9033.

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Pre-Filled Syringes and Injectable Drug Devices East Coast Conference and Exhibition

pharmaphorum

SAE Media Group's 11th Annual Pre-Filled Syringes East Coast Conference will return to Boston in April 2024 to bring you the latest advances in the combination product drug delivery space.

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Drug shortages challenge type 2 diabetes patients in the UK

Pharmaceutical Technology

Type-2 diabetes patients continue to be impacted by GLP-1 RA drug shortages in the UK with an NHS alert issuing guidelines on drug substitutions.