Fri.May 24, 2024

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New evidence supports fear that drinking raw milk containing bird flu viruses may be dangerous

STAT

A new study published Friday provides more evidence of the potential danger of drinking unpasteurized, or raw, milk containing H5N1 avian flu viruses. The work , published in the New England Journal of Medicine, showed that mice that were fed milk from H5N1-infected cows became very ill.

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Therapeutic areas where competition is heating up in pharma

PharmaVoice

The stage is set for potential blockbuster-level showdowns targeting these high-growth indications.

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STAT+: Ozempic cut risk of death in diabetes patients with chronic kidney disease

STAT

Novo Nordisk’s Ozempic cut the risk of death in a trial of patients with type 2 diabetes and chronic kidney disease, suggesting it may offer some added benefits over other classes of drugs approved to treat this population. Specifically, the diabetes drug cut the risk of cardiovascular-related deaths by 29% and all-cause deaths by 20%. Given the study parameters, this implies that over three years, 39 people would need to be treated to prevent one death from any cause, according to new re

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This week in clinical trials: 20th to 24th May

pharmaphorum

Exciting advancements in the world of clinical trials - Arecor Therapeutics, Faron, AstraZeneca, Volta Medical, J&J, Pneumagen, and Nimbus Therapeutics make headlines. Dive into this week's top stories impacting the future of medicine.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Nursing homes sue over Biden administration’s minimum staffing rule

STAT

A new federal lawsuit challenging the Biden administration’s new minimum nursing home staffing rule lays out the worst-case scenario: Hundreds of long-term care facilities forced to downsize or close, tens of thousands of vulnerable seniors displaced, and countless others waiting longer for care. Not only that, the complaint argues that the Centers for Medicare and Medicaid Services lacked the authority to implement the final rule.

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ASCO: AffyImmune claims a first with CAR-T for solid tumours

pharmaphorum

AffyImmune Therapeutics has recorded what it says is the first documented complete response in a patient with a solid tumour treated with CAR-T therapy. The case comes from a phase 1 study of its ICAM-1 targeting CAR-T autologous candidate AIC100 in patients with relapsed/refractory poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC), which will be reported at the ASCO congress next week.

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With Duchenne decision ahead, FDA’s Marks pushes for speedy gene therapy approvals

BioPharma Dive

But the head of the FDA’s CBER office didn’t tip where the agency stands on potentially broadening use of Sarepta’s Duchenne gene therapy Elevidys.

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Opinion: STAT+: Unmasking the ‘centricity’ illusion in clinical trials

STAT

During my 25 years working in clinical trial operations, I’ve seen the biopharmaceutical world talk a big game about making the process easier for the sites running the trials and the patients participating in them. Everyone from trial sponsors to the Food and Drug Administration has been quick to promise simpler processes, less hassle, and better experiences for everyone involved.

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ADC developer Pheon raises $120m, and other bio financings

pharmaphorum

This week’s round-up of biotech financings is led by a $120 million round for UK-based antibody-drug conjugate (ADC) developer Pheon, with SixPeaks also pulling in nine figures and smaller rounds for Progentos, LabGenius, and Grey Wolf, and Imvax.

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Opinion: Pandemic lessons must spur federal action to protect nursing home residents

STAT

About one-third of Americans who reach age 65 will need nursing home care in their lifetimes — which can be a daunting thought if you recall the suffering of residents as the Covid-19 pandemic exposed long-standing problems in nursing homes. These problems did not fade away with the end of the public health emergency, and nursing home residents continue to be disproportionately affected by Covid-19.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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King’s Doctoral Training Centre to investigate MS symptom management

Pharma Times

The lifelong autoimmune disease affects more than 150,000 people living in the UK

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More tumult at BIO amid the company’s fourth CEO in four years

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Morning! Today, we see some holes in the data for MDMA-assisted therapy, and ponder how that might impact the FDA’s upcoming decision over its approval. Also, the agency’s advisers debate Guardant’s colon cancer liquid biopsy test, and we see new data showing Ozempic’s efficacy in preventing death in diabetes and chronic kidney diseas

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New GPhC guide on gender services for children and young people

The Pharmacist

A new resource to support pharmacists and pharmacy technicians when providing services to children and young people with gender incongruence or dysphoria has been published by the regulator. The General Pharmaceutical Council (GPhC) has set out a range of questions pharmacy professionals should consider when making decisions about the supply of medicines in this context […] The post New GPhC guide on gender services for children and young people appeared first on The Pharmacist.

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FDA advisory committee reviews Novo Nordisk insulin icodec for T1D

Pharmaceutical Technology

The US FDA's EMDAC is set to hold a meeting to assess the benefit-risk profile of Novo Nordisk's insulin icodec, to treat type 1 diabetes.

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Pharmacies given powers to substitute whooping cough antibiotic amid supply disruption

The Pharmacist

The government has reactivated pharmacy powers to swap doses of clarithromycin due to ‘significant ongoing disruption’ to supplies. Pharmacies had been warning they were having to turn patients away and ask for new prescriptions from GPs amid increased demand for the antibiotic due to rising rates of whooping cough. Dr Leyla Hannbeck, the chief executive […] The post Pharmacies given powers to substitute whooping cough antibiotic amid supply disruption appeared first on The Pharmacist.

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ASCO: Merus bispecific garners attention after abstract drop

pharmaphorum

Shares in Merus spike on ASCO abstract on phase 2 trial of EGFRxLGR5 bispecific petosemtamab in head and neck cancer.

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A comprehensive approach to certification, quality control, and consumer trust in nutraceuticals

Express Pharma

Nutraceuticals, a blend of the words “nutrition” and “pharmaceuticals”, have proven to be a significant ally in the ever-changing field of health and wellness. These functional foods and dietary supplements, derived from natural food sources, provide more than just basic nutritional benefits. The wide range of nutraceuticals includes insoluble and soluble dietary fibres, probiotics, polyunsaturated fatty acids (PUFAs), antioxidant vitamins, polyphenols as well as various spices and herbs to cate

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NICE, NHS England unveil new pathway for medtech

pharmaphorum

NICE and NHS England are seeking feedback on proposed new rules and commissioning principles for medtech products.

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Agenda announced for FlyPharma Vienna 2024

Pharma Times

The conference will take place on 23 to 24 October at Vienna AirportCity

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Pharmacy First: Top tips for diagnosing and treating acute sinusitis

The Pharmacist

CLINICAL UPDATE The Pharmacy First service in England enables pharmacists to diagnose and treat seven specific conditions, with the aim of reducing current pressures on general practice. This series of guides assumes that pharmacists are familiar with the clinical pathways and requirements for Pharmacy First. The articles explore some key aspects of each service to […] The post Pharmacy First: Top tips for diagnosing and treating acute sinusitis appeared first on The Pharmacist.

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Innovent Biologics mazdutide can pave way for transformative T2D treatment: GlobalData

Express Pharma

Innovent Biologics has unveiled Phase III (DREAMS-2) results for mazdutide, indicating superiority over dulaglutide in glycaemic control for type 2 diabetes (T2D) patients in China. “With its potential to revolutionise T2D treatment, mazdutide’s success could not only reshape the landscape of diabetes therapeutics in China but also underscores the growing demand for innovative solutions amidst the escalating prevalence of T2D in the region,” says GlobalData.

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Merck KGaA Announces $600 Million Deal to Acquire Mirus Bio

PharmaTech

With this acquisition, Merck KGaA will have the capability to offer integrated services for viral vector manufacturing.

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Weight-loss jabs shouldn’t be quick-fix solution for governments, says expert

The Guardian - Pharmaceutical Industry

Obesity prevention is cheaper long-term option, says Cambridge professor, with focus on dietary advice and exercise plans Skinny jabs risk being used as a cop-out by governments to avoid making hard policy choices to prevent obesity, a leading expert has warned. Prof Giles Yeo, a geneticist at the University of Cambridge and expert on obesity and the brain control of food intake, said drugs such as semaglutide – the active ingredient in the weight-loss jab Wegovy – were remarkable and worked for

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Young people are increasingly using Wegovy and Ozempic

World Pharma News

Public interest in weight loss drugs like Wegovy and Ozempic is surging, but national data on dispensing patterns in the United States are surprisingly scarce. Now, a national study from Michigan Medicine shows that the use of these weight loss drugs is increasing rapidly in adolescents and young adults 12-25 years, especially females.

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Therapy reprogrammes immune cells to shrink prostate and bladder cancers

Pharma Times

JHU083 reduced tumour growth and triggered tumour cell death in mice

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ASCO 2024: Merus touts positive Phase II data for head and neck cancer antibody

Pharmaceutical Technology

Shares in Merus rose by 15% in premarket trading, following the announcement of positive Phase II data to be presented at ASCO.

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New patent expiration for Haleon Us drug CHILDREN’S ADVIL ALLERGY SINUS

Drug Patent Watch

Annual Drug Patent Expirations for CHILDREN%27S+ADVIL+ALLERGY+SINUS For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or visit www.DrugPatentWatch.

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Nona Biosciences announced agreement with AstraZeneca for tumour targeted therapies

Pharmafile

Nona Biosciences and AstraZeneca have announced that the two companies have entered into a license agreement for preclinical monoclonal antibodies, which will be used to create targeted therapies within oncology. The post Nona Biosciences announced agreement with AstraZeneca for tumour targeted therapies appeared first on Pharmafile.

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New patent expiration for Haleon Us drug CHILDREN’S ADVIL-FLAVORED

Drug Patent Watch

Annual Drug Patent Expirations for CHILDREN%27S+ADVIL-FLAVORED For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or visit www.DrugPatentWatch.

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FMCG Packaging Optimization in Seven Easy Steps

Pharma and Life Sciences Blog

FMCG Packaging Optimization in Seven Easy Steps Vijendra Fri, 05/24/2024 - 22:43 Packaging in the FMCG sector can account for up to 10% of input costs. However, without careful management, this percentage can climb significantly higher and eat into company profits. Every percentage point saved on packaging costs can translate into substantial financial gains.

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New patent expiration for Galderma Labs drug MIRVASO

Drug Patent Watch

Annual Drug Patent Expirations for MIRVASO Mirvaso is a drug marketed by Galderma Labs Lp and is included in one NDA. It is available from one supplier.

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Biogen to Acquire HI-Bio in Deal Worth Potentially Up to $1.8 Billion

PharmaTech

With the acquisition, Biogen gains felzartamab, HI-Bio's lead investigational mAb candidate being developed for the treatment of a range of immune-mediated diseases.

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New patent expiration for Abbvie drug LATISSE

Drug Patent Watch

Annual Drug Patent Expirations for LATISSE Latisse is a drug marketed by Abbvie and is included in one NDA. It is available from one supplier.

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The biosimilars dance: How drugmakers game the US patent system

pharmaphorum

The biosimilars dance has big pharma and regulators tangled in a complex patent battle. At stake: billions in profits and affordable access to vital meds.

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New patent for Otsuka drug INQOVI

Drug Patent Watch

Annual Drug Patent Expirations for INQOVI Inqovi is a drug marketed by Otsuka and is included in one NDA. It is available from one supplier.

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