Sat.May 18, 2024 - Fri.May 24, 2024

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New evidence supports fear that drinking raw milk containing bird flu viruses may be dangerous

STAT

A new study published Friday provides more evidence of the potential danger of drinking unpasteurized, or raw, milk containing H5N1 avian flu viruses. The work , published in the New England Journal of Medicine, showed that mice that were fed milk from H5N1-infected cows became very ill.

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Why AlphaFold 3 is stirring up so much buzz in pharma

PharmaVoice

The “Nobel Prize-worthy invention” could be worth hundreds of billions commercially — and have a deep impact on drug R&D.

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Researchers combine herpes virus with cancer vaccine to treat brain cancer in children

Pharma Times

High-grade gliomas are rare, malignant tumours which account for up to 12% of all childhood brain tumours

Vaccines 160
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Unlocking biotech insights: Top 10 podcasts you need to listen to

pharmaphorum

Unlocking biotech insights: discover the latest advancements in biotech with our top picks for podcasts. Stay informed and up-to-date with industry trends and news by listening to some of the best biotech podcasts featuring expert analysis, discussions of ethical issues, and interviews with industry leaders.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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New data show the HPV vaccine prevents cancer in men, too. Why don’t more people get it?

STAT

You’d think if there were a vaccine that would prevent tens of thousands of cases of cancer a year, people would want it for themselves and for their kids. But new data being released Thursday ahead of the annual meeting of the American Society of Clinical Oncology show that just isn’t the case.

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3 up-and-coming US biotech hotspots

PharmaVoice

These three U.S. cities are putting themselves on the biotech map as unsung hubs of the industry.

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This week in clinical trials: 20th to 24th May

pharmaphorum

Exciting advancements in the world of clinical trials - Arecor Therapeutics, Faron, AstraZeneca, Volta Medical, J&J, Pneumagen, and Nimbus Therapeutics make headlines. Dive into this week's top stories impacting the future of medicine.

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Michigan reports a human case of bird flu, the nation’s second linked to H5N1 outbreak in dairy cows

STAT

A second human case of bird flu infection linked to the current H5N1 outbreak in dairy cows has been detected, in a farm worker who had exposure to infected cows, Michigan state health authorities announced on Wednesday. In a statement , health officials said the individual had mild symptoms and has recovered. Evidence to date suggests this is a sporadic infection, with no signs of ongoing spread, the statement said.

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Pfizer and Lilly are elbowing into the direct-to-consumer market. Will it work?

PharmaVoice

Direct-to-consumer platforms offer consumers an online path to sourcing popular medications, but some therapeutic areas may be better suited for the business model.

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GP pharmacists in Wales to get structured induction programme

The Pharmacist

Pharmacists and pharmacy technicians transitioning to new roles in primary care are to be supported with a structured induction programme developed by Health Education and Improvement Wales (HEIW), it has said. The commitment came as part of the Welsh Government’s Strategic Workforce Plan for Primary Care for 2024/25-2029/30, published last week. The plan also committed […] The post GP pharmacists in Wales to get structured induction programme appeared first on The Pharmacist.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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ASCO: AffyImmune claims a first with CAR-T for solid tumours

pharmaphorum

AffyImmune Therapeutics has recorded what it says is the first documented complete response in a patient with a solid tumour treated with CAR-T therapy. The case comes from a phase 1 study of its ICAM-1 targeting CAR-T autologous candidate AIC100 in patients with relapsed/refractory poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC), which will be reported at the ASCO congress next week.

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UnitedHealth argues algorithm lawsuit should be dismissed because patients didn’t spend years appealing denials

STAT

UnitedHealth Group should be released from a lawsuit that alleges its algorithm-based technology prematurely cut off care to its Medicare Advantage members, the company said in court filings this week, because patients and their families did not finish Medicare’s appeals process. “Plaintiffs have failed to exhaust the exclusive administrative appeal process set by the Medicare Act,” UnitedHealth’s lawyers argued.

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Flipping a biotech incubator into a commercial company

PharmaVoice

How persistence led to BioLineRx’s first approved therapy and promising pipeline.

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Orna, a circular RNA specialist, acquires a buzzy startup

BioPharma Dive

After laying off staff late last year, Orna is expanding through the purchase of ReNAgade Therapeutics, which was built around technology designed to more effectively deliver RNA-based medicines.

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NICE and the controversy over a ‘clinically distinct disease’ designation

pharmaphorum

The debate rages on as NICE considers a 'clinically distinct disease' classification. Learn how this decision could reshape the STA process and patient treatment options.

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Wastewater testing specifically for bird flu virus will scale up nationally in coming weeks

STAT

Less than a month ago, researchers reported for the first time the ability to scan wastewater for signs of the H5 influenza virus currently sickening dairy cows in at least nine states across the U.S. That technology is now at the threshold of real-world use. WastewaterSCAN, an infectious disease-tracking sewage surveillance network led by Stanford University and Emory University in partnership with Verily Life Sciences, has begun scaling up H5-specific testing of samples from all of its 190 sit

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Three-quarters of people with learning disability not registered for GP practice support

The Pharmacist

Three-quarters of people with a learning disability are not currently on the general practice learning disability register, a new report published today by the Women and Equalities Committee (WEC) has suggested. MPs on the cross-party committee warned that people with a learning disability and autistic people faced significant health inequalities, including an ‘unacceptable level of […] The post Three-quarters of people with learning disability not registered for GP practice support appear

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ASCO24: An early look at cancer drug study results

BioPharma Dive

Clinical trial abstracts posted by ASCO Thursday give a peek at anticipated datasets from Immunocore, Merck & Co., J&J and Arcus Biosciences.

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FDA competition seeks digital endpoints for Parkinson’s

pharmaphorum

FDA is asking artificial intelligence teams to develop a digital endpoint tool to study freezing of gait, a symptom of Parkinson’s that can have a serious impact on patients.

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When should we start making H5N1 vaccine, and who will make that decision? In short, it’s complicated

STAT

If the H5N1 bird flu virus ever acquires the ability to transmit easily to and among people — keep your fingers crossed that it doesn’t — the world is going to need serious amounts of vaccine. Like, lakes of the stuff. Some manufacturers have been working with H5N1 viruses for years, producing small batches of doses that have undergone preliminary human testing.

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Menopause care needs all of our attention

The Pharmacist

There are many reasons why pharmacists should be leading providers of menopause advice and care in primary care – not least for their personal wellbeing – suggests pharmacist and menopause lead at NHS England, Bukky Ayoade As pharmacists, we are gatekeepers of healthcare, entrusted with the wellbeing of our patients. However, amid our commitment to […] The post Menopause care needs all of our attention appeared first on The Pharmacist.

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With Duchenne decision ahead, FDA’s Marks pushes for speedy gene therapy approvals

BioPharma Dive

But the head of the FDA’s CBER office didn’t tip where the agency stands on potentially broadening use of Sarepta’s Duchenne gene therapy Elevidys.

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PDURS explained: The FDA’s new framework for adding software to drug labels

pharmaphorum

In this fireside chat webinar, experts break down the FDA's new PDURS framework for adding software to drug labels. Learn how it impacts pharma and what you need to know. Join us on Tuesday 9th July @ 07:00am PDT / 10:00am EDT / 15:00pm BST / 16:00pm CEST.

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How doctors are pressuring sickle cell patients into unwanted sterilizations

STAT

BATON ROUGE, La. — The surgery was supposed to alleviate worry, but now, years later, Whitney Carter’s mind kept flicking back to it, wondering if it could be undone. She sometimes descended into these moods, taciturn, withdrawn, as if all hope had gone extinct. She sat on the couch in the half-light, blinds shut against the heat. The whole thing made her feel less than, like some essential part of her had been removed.

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Biogen Agrees to Acquire HI-BIO for $1.15 Billion

Pharmaceutical Commerce

The deal features felzartamab, an investigational anti-CD38 monoclonal antibody, whose clinical outcomes have shown potential to tackle various immune-mediated diseases.

Immunity 105
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Certain menopausal hormone therapy could raise ovarian cancer risk, study finds

BioPharma Dive

The findings, from two trials involving tens of thousands of women, could influence guidelines around the use of hormonal treatment for menopausal symptoms.

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Tony Blair Institute weighs in on use of NHS patient data

pharmaphorum

A think tank set up by former UK Prime Minister Tony Blair has called for the formation of a public-private trust that could oversee the sharing of anonymised patient data with trusted researchers.

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Move over, wastewater. Store-bought milk could be another way to track the bird flu outbreak in cows

STAT

Scientists from the University of Washington and the Fred Hutchinson Cancer Center have managed to generate a full genetic sequence of H5N1 virus from milk, a development they suggest means commercially purchased milk products could be used to monitor the progress of the bird flu outbreak in dairy cattle and to check for important changes in the virus over time.

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Who’s caring for those who care?

The Pharmacist

Phil Galt, a qualified pharmacist and managing director for Cegedim Rx, explores the mental health strain that pharmacists can face and asks, who’s caring for those who care? I’ve spent more than two decades working on the frontline of pharmacy. It’s always been a stressful environment and an intense workload is nothing new. But I’ve […] The post Who’s caring for those who care?

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Therapies designed to dismantle cancer’s escape mechanisms show promise for patients

BioPharma Dive

Hear from IO Biotech CEO Dr. Mai-Britt Zocca about the potential of therapeutic vaccines to strip the defenses used by cancer cells to keep the immune system at bay.

Immunity 111
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ATS: Amgen, AZ say data backs Tezspire’s role in COPD

pharmaphorum

Amgen and AstraZeneca have said their severe asthma therapy Tezspire could have a role to play in chronic obstructive pulmonary disease (COPD) – a key target indication for the drug – despite missing its primary objective in a clinical trial.

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CDC asks states and cities to keep flu surveillance at peak levels because of bird flu threat

STAT

The Centers for Disease Control and Prevention asked local and state health officials Tuesday to maintain flu surveillance operations at peak-season levels over the summer in a bid to remain watchful for any signs of human-to-human spread of the H5N1 bird flu virus. Flu surveillance activity is generally conducted at low levels during the late spring and summer months, in recognition of the fact that as temperatures rise, transmission of seasonal flu viruses drops to minimal levels in the Northe

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King’s Doctoral Training Centre to investigate MS symptom management

Pharma Times

The lifelong autoimmune disease affects more than 150,000 people living in the UK

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AstraZeneca sets sights on $80B in revenue by 2030

BioPharma Dive

The U.K. pharma expects to launch 20 new drugs by then, among them complex medicines for cancer as well as treatments for weight loss.

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Cytokinetics eyes go-it-alone strategy for aficamten

pharmaphorum

Cytokinetics has been a top biotech takeover candidate for some time, thanks to blockbuster speculation about its lead drug aficamten, but a $1 billion-plus set of financing deals shows it is prepared to go to market on its own.

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