Pharmacist Digest

Opinion: Medical students lose in the research arms race for residency slots

STAT

APRIL 29, 2024

I’d rather use the time to do research,” one of my classmates told me during the first week of my first year of medical school. “Going to medical Spanish class really isn’t worth my time. Such a comment was my introduction to the publish-or-perish environment that is increasingly pervasive amongst medical students.

Medical Schools

Medical Schools Communication

STAT+: A flurry of research misconduct cases has universities scrambling to protect themselves

STAT

FEBRUARY 12, 2024

There was a time when an allegation of data mishandling, scientific misconduct, or just a technical error felt like a crisis to Barrett Rollins, an oncologist and research integrity officer at Dana-Farber Cancer Institute. Now, it’s a Tuesday. And it’s hardly alone.

Fetal tissue research gains in importance as roadblocks multiply

STAT

MARCH 20, 2024

She warily monitors the state legislature, where there is ongoing debate, and therefore uncertainty, over changes to rules governing fetal tissue research. “It seems too risky,” she said. And much is riding on the outcome of the November presidential election. Read the rest…

Why researchers think human milk could repair the gut microbiome and reduce infections

STAT

MARCH 29, 2024

Researchers who study human milk understand how the molecules affect everything from the gut microbiome to curbing chronic disease risk factors in babies. That milk could also lower the risk of asthma , diabetes, and allergies. Read the rest…

Diabetes

Listen: Controversial brain tissue research, obesity drug sales, and Novartis’ M&A drama

STAT

MAY 2, 2024

The removal of small amounts of brain tissue from desperately ill patients, done as part of a Mount Sinai research project, triggered alarm bells at the Food and Drug Administration and has raised broader questions about the scientific and ethical justification for live-brain research.

Opinion: Lessons for scientists from the All of Us Research Program backlash

STAT

MARCH 15, 2024

What we are not usually trained to navigate, however, is public backlash, which is exactly what followed the publication of the comprehensive genomic sequencing results from the All of Us Research Program. At the heart of the matter is how the study presented the diversity of race and ethnicity in their dataset.

Q&A: The scientific integrity sleuth taking on the widespread problem of research misconduct

STAT

FEBRUARY 28, 2024

Bik first became interested in plagiarism as a hobby while working as a researcher at Stanford University in 2013. She later began specializing in image duplication specifically, which she believes is a more serious problem for science as a whole.

NCI director expresses optimism about next era of cancer research, despite shrinking budget and brain drain

STAT

APRIL 10, 2024

SAN DIEGO — Kimryn Rathmell, director of the National Cancer Institute, gestured toward the screen and asked an audience of clinicians, researchers, and patient advocates what they thought they were looking at. Projected behind her was a patchwork of purple, red, pink, and blue squares.

STAT+: House moves to limit so-called gain-of-function research

STAT

NOVEMBER 15, 2023

ban on controversial infectious disease research to legislation that could ultimately fund federal health agencies like the National Institutes of Health. The spending bill already included a restriction on funding this research in any country determined to be a “foreign adversary,” including China.

STAT+: FDA is still struggling to inspect clinical research sites, watchdog finds

STAT

MARCH 26, 2024

Food and Drug Administration’s oversight of clinical research in hospitals and clinics has fallen considerably in recent years, due to disruptions caused by the Covid pandemic and challenges finding and keeping investigators, according to a new report by the U.S. Government Accountability Office.

Hospitals

The latest updates on cancer research from the weekend

STAT

APRIL 8, 2024

We have news for you from the annual meeting of the American Association for Cancer Research, and also from the annual meeting of the American College of Cardiology. Sign up to get our biotech newsletter in your inbox. Hi, it’s Meghana. Lots happened this past weekend! Interesting stuff. Read the rest…

Opinion: Congress could stop free public access to government-funded research

STAT

SEPTEMBER 28, 2023

Have you ever needed to read a research paper, only to find it was locked behind a paywall? Your next step was likely to search on Sci-Hub , an illegal repository created by Kazakh graduate student Alexandra Elbakyan, that provides free access to millions of research papers. Read the rest…

STAT+: New proposals for scientific misconduct investigations worry some research universities

STAT

DECEMBER 8, 2023

Research universities are voicing concerns over some proposed changes to the process for reviewing scientific misconduct allegations, citing worries that new government requirements would hobble their own independent procedures and constitute a huge administrative burden. The proposed changes, published on Oct.

STAT+: MD Anderson tried — and failed — to resolve research credit dispute between two scientists, new documents show

STAT

FEBRUARY 26, 2024

Early last year, MD Anderson Cancer Center leadership had a problem on their hands: a contentious dispute between one of its most powerful researchers and a junior scientist over authorship, credit, and charges of verbal abuse. These documents are alluded to in legal filings but have not been previously reported.

Documentation

Opinion: New CMS rules will throttle access researchers need to Medicare, Medicaid data

STAT

FEBRUARY 20, 2024

Groundbreaking research more than a decade ago showed that almost one-fifth of people enrolled in Medicare were being readmitted within 30 days after being discharged from the hospital, harming patients and increasing costs. That study led to a sea change in health care.

Hospitals

STAT+: Ibogaine, the psychedelic, unlikely to receive approval as opioid treatment, says top addiction researcher

STAT

MARCH 21, 2024

The psychedelic ibogaine is unlikely to ever receive approval as a treatment for opioid addiction, the federal government’s top addiction researcher said Thursday.

Opinion: Readers respond to funding academic medical centers, the ‘residency research arms race,’ and more

STAT

MAY 4, 2024

“Medical students lose in the research arms race for residency slots,” by Anmol Shrestha Read the rest… STAT now publishes selected Letters to the Editor received in response to First Opinion essays to encourage robust, good-faith discussion about difficult issues.

Hospitals

STAT+: Researchers create talking throat patch for people with voice disorders

STAT

MARCH 12, 2024

Researchers at the University of California, Los Angeles have built a soft, adhesive patch capable of turning throat movements into speech. The patch, written about in a paper published in Nature Communications on Tuesday, is made out of a material that converts motion into electricity.

Communication

STAT+: In a scientific first, researchers use CRISPR base editing to treat liver disease in fetal monkeys

STAT

APRIL 22, 2024

The research, by a team at the University of Pennsylvania and the Children’s Hospital of Philadelphia (CHOP), will be presented next month at the annual meeting of the American Society of Gene and Cell Therapy, potentially paving the way for human trials.

Packaging

Packaging Hospitals

STAT+: Life scientists’ flight to biotech labs stalls important academic research

STAT

NOVEMBER 15, 2023

That’s because Sheybani has been unable to hire a postdoctoral researcher since starting her lab in 2021. Academia is in the midst of an unprecedented exodus of life science researchers, many of whom are leaving for lucrative jobs in the private sector. But in each case the candidate opted for a job at a biotech company.

STAT+: Dana-Farber cancer researchers moving to retract one paper, correct others in broad investigation of manipulated data

STAT

JANUARY 19, 2024

Scientists at Dana-Farber Cancer Institute, one of the nation’s leading cancer research and treatment centers, are “moving to” retract one paper and correct others amid an expanding investigation of data manipulation, officials told STAT.

Hospitals

STAT+: A junior scientist. A prominent oncologist. Now, a clash at MD Anderson over who gets research credit

STAT

FEBRUARY 8, 2024

It was a promising start, but that’s when Lin says one of the Texas institute’s most powerful researchers interfered. “I’m sure that my career in research has just fallen off a cliff.” ” Continue to STAT+ to read the full story…

Male birth control research wins audience over at STAT Madness event

STAT

MARCH 22, 2024

What happens when too many excellent, pioneering researchers enter a room? A little madness.

STAT+: Why Novartis is changing the name of its research labs

STAT

SEPTEMBER 8, 2023

Swiss drugmaker Novartis’ research and development hub has a new name — and a new guiding strategy. and for years has been known as Novartis Institutes for BioMedical Research, or NIBR, will soon simply be known as Novartis BioMedical Research. The hub, which is headquartered in Cambridge, Mass.,

Drug Development

Renamed, common liver diseases might get fairer shake at treatment, researchers hope

STAT

DECEMBER 28, 2023

Experts hope the change can generate more conversation — and research interest — for conditions that still lack treatments. A slate of liver diseases got a rebrand this year.

STAT+: New proposals for scientific misconduct investigations worry some research universities

STAT

DECEMBER 8, 2023

Research universities are voicing concerns over some proposed changes to the process for reviewing scientific misconduct allegations, citing worries that new government requirements would hobble their own independent procedures and constitute a huge administrative burden. The proposed changes, published on Oct.

STAT+: Leading MD Anderson oncologist disputes junior scientist’s claims in lawsuit over research credit

STAT

FEBRUARY 16, 2024

The filing, which was submitted by Texas Attorney General Ken Paxton and lawyers in his office, also argued that the junior researcher’s lawsuit should be made against MD Anderson, not Sharma, and asked the court to dismiss the suit if it is not amended within 30 days. “Dr.

Immunity

Immunity Immunization

In pigs, researchers show ultrasound could be used for 3D printing inside the body

STAT

DECEMBER 7, 2023

Researchers at Duke University and Harvard Medical School have successfully demonstrated a proof of concept in new research published Thursday in Science using a 3D printer that uses ultrasound to print biomaterials inside an organ. Imagine getting surgery without ever being cut open.

Medical Schools

The ‘Hispanic Paradox’ intrigues a new generation of researchers determined to unravel it

STAT

SEPTEMBER 14, 2023

For 40 years, researchers have unsuccessfully tried to explain — or debunk — the “Hispanic Paradox,” the finding that Hispanic Americans live several years longer than white Americans on average, despite having far less income and health care and higher rates of diabetes and obesity.

Diabetes

STAT+: From a small town in Wales, a scientific sleuth has shaken Dana-Farber — and elevated the issue of research integrity

STAT

JANUARY 27, 2024

PONTYPRIDD, Wales — The blog post that has shaken the leadership of Boston’s Dana-Farber Cancer Institute, one of the world’s preeminent cancer research centers, was written some 3,000 miles away, in a bare-walled, sparsely decorated flat, save for a stack of statistics books and a collection of Rubik’s Cubes.

STAT+: NIH systems for non-human primate research fall short, threatening biomedical research

STAT

MAY 4, 2023

A worsening shortage of non-human primates and an inadequate government response threatens to undermine biomedical research in the U.S. of the animals used in biomedical research, but can be very valuable due to their similarities to humans on genetic, anatomic, physiologic, and behavioral levels.

Pfizer isn’t sharing Covid vaccines with researchers for next-gen studies

STAT

SEPTEMBER 6, 2022

WASHINGTON — Researchers studying next-generation vaccines to fight an evolving Covid-19 threat are running into problems getting existing vaccines to use in their research. Right now, Pfizer isn’t sharing its vaccines for research purposes, a spokesperson confirmed to STAT. Read the rest…

Vaccines

Opinion: AI-driven data analysis could exacerbate misaligned incentives in biomedical research

STAT

SEPTEMBER 29, 2023

“ It aims to be nothing short of the ideal statistical collaborator or research software engineer, providing the necessary skill and speed to overcome the limitations of one’s research program at a fraction of the price.

Mistakes happen in research papers. But corrections often don’t

STAT

JANUARY 10, 2023

Mistakes happen — in life, in the lab, and, inevitably, in research papers, too. But one particularly high-profile case is now drawing fresh attention to the problems with journals’ process for addressing concerns about research integrity. Journals use corrections and retractions to resolve those mistakes.

2023 Nobel Prize in Medicine: Karikó, Weissman awarded prize for mRNA research

STAT

OCTOBER 2, 2023

LONDON — Two pioneers of mRNA research — the technology that helped the world tame the virus behind the Covid-19 pandemic — won the 2023 Nobel Prize in medicine or physiology on Monday.

Immunity

Immunity Immunization Vaccines

It’s time to stop treating menopause like a disease, researchers argue in series of Lancet articles

STAT

MARCH 5, 2024

The essay’s authors call for better education, more non-medical ways to address menopause, and more research into all available treatments, not just products that drug companies are eager to promote. Read the rest…

With latest tranche, U.K. Biobank has genome sequences from 500,000 people available for research

STAT

NOVEMBER 29, 2023

LONDON — Data from half a million people’s whole genome sequences are now available to researchers worldwide, as the U.K. Biobank on Thursday debuted the latest addition to what it aims to be the world’s most comprehensive health data resource.

Medical Records

Opinion: Can Arena Bioworks upend the traditional scientific research model in the U.S.?

STAT

FEBRUARY 2, 2024

I’ve spent a good deal of my career thinking about how we structure and fund research in the biomedical sciences in the U.S. model of embedding research in universities is the right one. and questioning whether the U.S. So to me, the launch of Arena BioWorks is welcome news. between MIT and Harvard.

Researchers use AI to measure recovery from treatment-resistant depression

STAT

SEPTEMBER 20, 2023

Researchers say they’ve been able to measure recovery from treatment-resistant depression through brain scans — a crucial step toward quantifying the impact of therapies on a condition whose progress is notoriously difficult to measure objectively. And that’s thanks to generative AI , they say.

STAT+: CRISPR-edited pig liver from eGenesis passes first test in brain-dead human, researchers say

STAT

JANUARY 18, 2024

The experiment, designed to test whether a genetically engineered porcine liver kept alive in a box could support the circulatory system of a human, was a resounding success, the research team said Thursday. Continue to STAT+ to read the full story…

Hospitals

STAT+: Was CAR-T therapy a bystander or driver of lymphoma? Researchers examine first published case

STAT

DECEMBER 9, 2023

SAN DIEGO — Researchers on Saturday presented an unusual case of a T cell lymphoma marked with a CAR, the key synthetic protein in CAR-T therapy, here at the American Society of Hematology annual meeting.

New research supports potential link between low-level lead exposure and liver injury

STAT

NOVEMBER 27, 2023

Nearly a decade on, the Flint water crisis still looms large in the minds of environmental toxin researchers. It was — and continues to be — evidence that not all communities in the United States are equally affected by environmental pollutants.

STAT+: Amylyx ALS drug failure leaves patients, advocates, and researchers reeling — and wondering what’s next

STAT

MARCH 8, 2024

The latest disappointment in amyotrophic lateral sclerosis research brought crushing news for patients and physicians, forcing the community to consider just what to do with an approved medicine that doesn’t appear to work.

Drug Development

STAT+: In boon for scientists, U.K. strikes deal to join E.U. Horizon research program

STAT

SEPTEMBER 7, 2023

’s landmark Horizon research initiative , a move that will allow British scientists and companies to win funding from and collaborate with their European peers in the $100 billion program. Researchers and business groups have been calling for such a deal for months, warning that without membership, the U.K.

Opinion: Medical students lose in the research arms race for residency slots

STAT+: A flurry of research misconduct cases has universities scrambling to protect themselves

Trending Sources

Fetal tissue research gains in importance as roadblocks multiply

Why researchers think human milk could repair the gut microbiome and reduce infections

Listen: Controversial brain tissue research, obesity drug sales, and Novartis’ M&A drama

Opinion: Lessons for scientists from the All of Us Research Program backlash

Q&A: The scientific integrity sleuth taking on the widespread problem of research misconduct

NCI director expresses optimism about next era of cancer research, despite shrinking budget and brain drain

STAT+: House moves to limit so-called gain-of-function research

STAT+: FDA is still struggling to inspect clinical research sites, watchdog finds

The latest updates on cancer research from the weekend

Opinion: Congress could stop free public access to government-funded research

STAT+: New proposals for scientific misconduct investigations worry some research universities

STAT+: MD Anderson tried — and failed — to resolve research credit dispute between two scientists, new documents show

Opinion: New CMS rules will throttle access researchers need to Medicare, Medicaid data

STAT+: Ibogaine, the psychedelic, unlikely to receive approval as opioid treatment, says top addiction researcher

Opinion: Readers respond to funding academic medical centers, the ‘residency research arms race,’ and more

STAT+: Researchers create talking throat patch for people with voice disorders

STAT+: In a scientific first, researchers use CRISPR base editing to treat liver disease in fetal monkeys

STAT+: Life scientists’ flight to biotech labs stalls important academic research

STAT+: Dana-Farber cancer researchers moving to retract one paper, correct others in broad investigation of manipulated data

STAT+: A junior scientist. A prominent oncologist. Now, a clash at MD Anderson over who gets research credit

Male birth control research wins audience over at STAT Madness event

STAT+: Why Novartis is changing the name of its research labs

Renamed, common liver diseases might get fairer shake at treatment, researchers hope

STAT+: New proposals for scientific misconduct investigations worry some research universities

STAT+: Leading MD Anderson oncologist disputes junior scientist’s claims in lawsuit over research credit

In pigs, researchers show ultrasound could be used for 3D printing inside the body

The ‘Hispanic Paradox’ intrigues a new generation of researchers determined to unravel it

STAT+: From a small town in Wales, a scientific sleuth has shaken Dana-Farber — and elevated the issue of research integrity

STAT+: NIH systems for non-human primate research fall short, threatening biomedical research

Pfizer isn’t sharing Covid vaccines with researchers for next-gen studies

Opinion: AI-driven data analysis could exacerbate misaligned incentives in biomedical research

Mistakes happen in research papers. But corrections often don’t

2023 Nobel Prize in Medicine: Karikó, Weissman awarded prize for mRNA research

It’s time to stop treating menopause like a disease, researchers argue in series of Lancet articles

With latest tranche, U.K. Biobank has genome sequences from 500,000 people available for research

Opinion: Can Arena Bioworks upend the traditional scientific research model in the U.S.?

Researchers use AI to measure recovery from treatment-resistant depression

STAT+: CRISPR-edited pig liver from eGenesis passes first test in brain-dead human, researchers say

STAT+: Was CAR-T therapy a bystander or driver of lymphoma? Researchers examine first published case

New research supports potential link between low-level lead exposure and liver injury

STAT+: Amylyx ALS drug failure leaves patients, advocates, and researchers reeling — and wondering what’s next

STAT+: In boon for scientists, U.K. strikes deal to join E.U. Horizon research program

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