article thumbnail

Treatment options for Crohn’s disease expand after Rinvoq approval

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has approved AbbVie’s Rinvoq (upadacitinib) for patients with Crohn’s disease who do not respond to TNF blockers, a common immune suppressant treatment for the condition. In patients with severe symptoms, a dosage of 30mg can be considered.

article thumbnail

EMA CHMP recommends authorisation of AstraZeneca’s Evusheld for Covid-19

Pharmaceutical Technology

In the region, the dosage advised for usage is 300mg separate, intramuscular (IM) injections of tixagevimab and cilgavimab, given in a sequential manner. This therapy is intended to treat adult and adolescent Covid-19 patients aged 12 years and above, who do not need additional oxygen and are at greater disease progression risk.

Dosage 111
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

A Comprehensive Guide to Vitamins

FADIC

Vitamin A Role of Vitamin A : Vitamin A has many vital functions in your body: It strengthens your immune system. It helps your muscles move and supports your immune system. ‌ Vitamin E Role of Vitamin E : Vitamin E supports your immune system and prevents blood clots. It’s essential for your vision.

article thumbnail

First-in-class plaque psoriasis oral therapy approved in EU

European Pharmaceutical Review

These are key cytokines involved in the pathogenesis of multiple immune-mediated diseases. Dosage for Otezla was 30mg twice daily. Sotyktu targets TYK2 and inhibits the signalling of interleukin (IL)-23, IL-12 and Type 1 interferons (IFN). At therapeutic doses, Sotyktu does not inhibit Janus kinase ( JAK)1, JAK2 or JAK3.

Dosage 93
article thumbnail

Off-label Use

RX Note

To verify the dosage and off-label use, you may check-up these drug references: Lexicomp - personal preference British National Formulary and BNF for Children Micromedex Medscape Epocrates Yup, technically, you should not look up product leaflet for off-label use (and its dosage). paediatric, pregnant, or psychiatric patients).

article thumbnail

Brazil grants authorisation for Sinovac’s Covid-19 vaccine in children

Pharmaceutical Technology

Subjects in this age group can receive the same vaccine dosage authorised in patients aged six to 17 years, as well as adults. The Brazilian Health Regulatory Agency (Anvisa) has granted emergency use authorization for Sinovac Biotech’s Covid-19 vaccine, CoronaVac, in children aged three to five years.

article thumbnail

FDA approves Adstiladrin as first gene therapy for NMIBC

pharmaphorum

Dosage of Adstiladrin was given once every three months – administered into the bladder via a urinary catheter – for up to 12 months, or until unacceptable toxicity to therapy or recurrent high-grade NMIBC. Individuals who are immunosuppressed or immune-deficient should not come into contact with Adstiladrin.

Dosage 118